Bovine spongiform encephalopathy, Biology

Assignment Help:

Bovine spongiform encephalopathy

The bovine transmissible spongiform encephalopathy (BSE), known as 'mad cow disease'-first noticed in Great Britain in 1986, is similar to scrapie in sheep and Creustfeld Jacob syndrome (CJD) in man, chronic wasting disease of captive mule deer and rocky mountain elk and transmissible encephalopathies in mink. It has been reported from Northern Ireland, the Republic of Ireland, Oman, Switzerland, France, Germany and a few other European countries. There is no report of BSE in India so far although doubtful cases of CJD in human beings have been reported. The causative agent is structurally different from a virus in that it contains protein (PrP) which is a transformed naturally occurring protein constituent of neurons that is encoded by a single chromosomal gene and devoid of nucleic acid. This agent measures 30-50 nm and is extremely resistant to inactivation by heating, UV-irradiation and many chemicals. BSE is classified as Prion disease.


Epidemiology: The disease in cattle occurred as a result of feeding them with ruminant protein supplements in meat and bone-meal derived from scrapie-affected sheep.


Symptoms:
It is difficult to diagnose the disease on the basis of clinical signs since such signs are not quite spectacular. Histopathological and histochemical studies, electron microscopy and biochemical analysis for detection of prion protein are presently available for laboratory confirmation of the disease.Prevention, control and treatment: Identification and slaughtering of positive and suspected cases are the only means of control measures available at present


Related Discussions:- Bovine spongiform encephalopathy

Pathophysiology of aortic regurgitation, Q. Pathophysiology of aortic regur...

Q. Pathophysiology of aortic regurgitation? Left ventricle responds to chronic aortic regurgitation by chamber dilatation and an increase in its compliance so that end diastoli

Zoonoses disease-cryptococcosis, Cryptococcosis An opportunistic infect...

Cryptococcosis An opportunistic infection, caused by Cryptococcus neoformans is affecting immunocompromised individuals mainly with impaired cell mediated immunity. The disease

Safety measures in the administration of drugs, SAFETY MEASURES IN THE ADMI...

SAFETY MEASURES IN THE ADMINISTRATION OF DRUGS It is essential to revise the five "Rights" before administration of medication to the paediatric group. These as you know are:

Feline panleukopenia, Feline panleukopenia It is arguably the most importa...

Feline panleukopenia It is arguably the most important of all feline viral diseases and all members of the family Felidae are susceptible. This disease is commonly found in kitten

Explain the course of events during spontaneous blinking, Explain about the...

Explain about the course of events during spontaneous blinking. Course of Events during Spontaneous Blinking: Given ate the course of events which take place in the

Explain nicotinamide nucleotides, Nicotinamide nucleotides These coenzy...

Nicotinamide nucleotides These coenzymes are derived from  the vitamin, niacin. They are of two  types, nicotinamide  adenine dinucleotide (NAD')  and nicotinamide adenine dinu

Explain about the shade drying, Explain about the Shade Drying? Shade d...

Explain about the Shade Drying? Shade drying is carried out for products which can lose their colour and/or turn brown if put in direct sunlight. Products that have naturally v

Determinants of health status, Determinants of Health Status The linkage...

Determinants of Health Status The linkage between economic development and health was discussed in the previous unit. The present unit deals with an identification of the factor

The glomerular filtrate in comparison to the blood, What is the main transf...

What is the main transformation presented by the glomerular filtrate in comparison to the blood? Glomerular filtrate is the name given to the plasma after it has passed the glo

Explain about homeostatic regulation, What is an example of negative feebac...

What is an example of negative feeback of the homeostatic regulation? Negative feedback happens when the response to a given action makes an effect that inhibits that action. F

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd