Bovine spongiform encephalopathy, Biology

Assignment Help:

Bovine spongiform encephalopathy

The bovine transmissible spongiform encephalopathy (BSE), known as 'mad cow disease'-first noticed in Great Britain in 1986, is similar to scrapie in sheep and Creustfeld Jacob syndrome (CJD) in man, chronic wasting disease of captive mule deer and rocky mountain elk and transmissible encephalopathies in mink. It has been reported from Northern Ireland, the Republic of Ireland, Oman, Switzerland, France, Germany and a few other European countries. There is no report of BSE in India so far although doubtful cases of CJD in human beings have been reported. The causative agent is structurally different from a virus in that it contains protein (PrP) which is a transformed naturally occurring protein constituent of neurons that is encoded by a single chromosomal gene and devoid of nucleic acid. This agent measures 30-50 nm and is extremely resistant to inactivation by heating, UV-irradiation and many chemicals. BSE is classified as Prion disease.


Epidemiology: The disease in cattle occurred as a result of feeding them with ruminant protein supplements in meat and bone-meal derived from scrapie-affected sheep.


Symptoms:
It is difficult to diagnose the disease on the basis of clinical signs since such signs are not quite spectacular. Histopathological and histochemical studies, electron microscopy and biochemical analysis for detection of prion protein are presently available for laboratory confirmation of the disease.Prevention, control and treatment: Identification and slaughtering of positive and suspected cases are the only means of control measures available at present


Related Discussions:- Bovine spongiform encephalopathy

Explain adverse effects of ribavirin, Adverse Effects of Ribavirin  Sys...

Adverse Effects of Ribavirin  Systemic ribavirin has been associated with hemolytic anemia. Oral ribavirin plus interferon appears to cause a higher incidence of cough, pruritu

Effect of environmental factors-sexual reproduction, Effect of Environmenta...

Effect of Environmental Factors some lower organisms, though the genetic determiners of the sexes are present, the ambient environment plays a decisive role in the development

Pituitary gland, PITUITARY GLAND (HYPOPHYSIS CEREBRI) - It develops ...

PITUITARY GLAND (HYPOPHYSIS CEREBRI) - It develops from ectoderm of the embryo. The pituitary gland is located just below the hypothalamus. The pituitary gland is situate

Adenine and thymine in complementary strands dna molecule, A "phosphodieste...

A "phosphodiester bond" links together: Answer the 3' hydroxyl group and the N9 atom of adenine in ATP. The Phosphate group and N9 atom of adenine in ATP. Sequential nucleosides in

What are the vascular bundles, What are the vascular bundles? How does conf...

What are the vascular bundles? How does configuration of the vascular bundles within the stem differentiate monocots from dicots? The Vascular bundles are segments of xylem and

#classification of parasitic protozoa.., most recent classification of para...

most recent classification of parasitic protozoa with its general characters

Surface water sources and charactersitics, Most of the surface water origin...

Most of the surface water originates directly from precipitation in the form of rainfall or snow. Ground water from springs also contributes to the flow of most of the streams. The

Regents for estimation of reducing sugar by fehling soxhlet, Define Regents...

Define Regents for Estimation of Reducing Sugar by Fehling Soxhlet Method? Fehling A solution - copper sulphate solution Fehling B solution - alkaline tartarate so

Determine the antagonist of the glycine receptor, Person Z swallowed a larg...

Person Z swallowed a large amount of substance X and, as a result, has convulsions (abnormal violent contractions of skeletal muscles).  Swallowing which of the following substance

Monocotyledonous embryo, Monocotyledonous Embryo The early developmen...

Monocotyledonous Embryo The early development of the proembryo in monocots follows the same pattern as in the dicots. However, at the time of differentiation in the globular

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd