Bovine spongiform encephalopathy, Biology

Assignment Help:

Bovine spongiform encephalopathy

The bovine transmissible spongiform encephalopathy (BSE), known as 'mad cow disease'-first noticed in Great Britain in 1986, is similar to scrapie in sheep and Creustfeld Jacob syndrome (CJD) in man, chronic wasting disease of captive mule deer and rocky mountain elk and transmissible encephalopathies in mink. It has been reported from Northern Ireland, the Republic of Ireland, Oman, Switzerland, France, Germany and a few other European countries. There is no report of BSE in India so far although doubtful cases of CJD in human beings have been reported. The causative agent is structurally different from a virus in that it contains protein (PrP) which is a transformed naturally occurring protein constituent of neurons that is encoded by a single chromosomal gene and devoid of nucleic acid. This agent measures 30-50 nm and is extremely resistant to inactivation by heating, UV-irradiation and many chemicals. BSE is classified as Prion disease.


Epidemiology: The disease in cattle occurred as a result of feeding them with ruminant protein supplements in meat and bone-meal derived from scrapie-affected sheep.


Symptoms:
It is difficult to diagnose the disease on the basis of clinical signs since such signs are not quite spectacular. Histopathological and histochemical studies, electron microscopy and biochemical analysis for detection of prion protein are presently available for laboratory confirmation of the disease.Prevention, control and treatment: Identification and slaughtering of positive and suspected cases are the only means of control measures available at present


Related Discussions:- Bovine spongiform encephalopathy

Electrophoresis gel to load 60, Assume your tilapia fish muscle homogenate ...

Assume your tilapia fish muscle homogenate has a protein concentration of 5769 ?g/ml. You take 32.5 ?l of this fish homogenate, mix it with 12.5 ?l sample buffer and 5 ?l reducing

A monohybrid cross, A monohybrid cross: A.Determines the genetic makeup of ...

A monohybrid cross: A.Determines the genetic makeup of an organism B.always involves homozygous alleles. C.always involves organisms that are heterozygous at all loci. D.Always inv

Edema, Ed e m a It refers to excessive accumulation of fluid in tiss...

Ed e m a It refers to excessive accumulation of fluid in tissue spaces caused by disturbance in the fluid interchange between capillaries, tissue spaces and lymphatic vessel

Health stroke scale, Health Stroke Scale: Stroke is a leading cause of...

Health Stroke Scale: Stroke is a leading cause of death, hospitalization, disability and health care expenditure in U.S. (Fonarow G. et al., 2012).  Stroke is a medical condit

Respiration, difference between anaerobic respiration and fermentation

difference between anaerobic respiration and fermentation

Define classification of carbohydrates - oligosaccharides, Define classific...

Define classification of carbohydrates - Oligosaccharides? Oligosaccharides are short chains of saccharide units and are condensation products of three to ten monosaccharides.

Double fertilization, Double fertilization  It carries two sperm cells to t...

Double fertilization  It carries two sperm cells to the female. A characteristic of angiosperms in which the pollen tube gametophyte in the ovule. The one sperm cell fuses with the

Major classes into which the phylum is divided, Q What are the major classe...

Q What are the major classes into which the phylum is divided? What are the few examples of each and in which form (polyp or medusae) are they found? Coelenterates are divided

Define the term- organismal complexity, Which of the following statements l...

Which of the following statements least accurately explains our knowledge of how gene number relates to "organismal complexity"? A. Based on known gene numbers there appears to

Growth and development, details and terms used in growth and development?

details and terms used in growth and development?

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd