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Blinding: A procedure used in clinical trials to get rid of the possible bias which might be introduced if the patient and/or the doctor knew which treatment the patient is receiving. If neither the patient nor the doctor are aware of which treatment has been given the trial is known as double-blind. If only one out of the patient or doctor is unaware of the treatment, then the trial is called single-blind. Clinical trials should use maximum degree of blindness which is possible, even though in some areas, for instance, surgery, it is often not possible for an investigation to be double-blind.
The problematic and enigmatic theory of an inference introduced by the Fisher, which extracts a probability distribution for the parameter on the basis of the data without having f
Categorical variable : A variable which provides the appropriate label of observation after the allocation to one of the several possible categories, for instance, the respiratory
Continual reassessment method: An approach which applies Bayesian inference for determining the maximum tolerated dose in a phase I trial. The method starts by assuming a logistic
4-13. Students in a management science class have just received their grades on the first test. The instructor has provided information about the first test grades in some previou
Normality - Reasons for Screening Data Prior to analyzing multivariate normality, one should consider univariate normality Histogram, Normal Q-Qplot (values on x axis
Why Graph theory? It is the branch of mathematics concerned with the properties of sets of points (vertices or nodes) some of which are connected by the lines known as the edges. A
Regression dilution is the term which is applied when a covariate in the model cannot be measured directly and instead of that a related observed value must be used in analysis. I
Unequal probability sampling is the sampling design in which the different sampling units in the population have different probabilities of being included in sample. The differing
Multicentre study : The clinical trial conducted simultaneously in the number of participating hospitals, with all centres following an agreed-upon study of the protocol and with
Intention-to-treat analysis is the process in which all the patients randomly allocated to a treatment in the clinical trial are analyzed together as representing that particular
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