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Blinding: A procedure used in clinical trials to get rid of the possible bias which might be introduced if the patient and/or the doctor knew which treatment the patient is receiving. If neither the patient nor the doctor are aware of which treatment has been given the trial is known as double-blind. If only one out of the patient or doctor is unaware of the treatment, then the trial is called single-blind. Clinical trials should use maximum degree of blindness which is possible, even though in some areas, for instance, surgery, it is often not possible for an investigation to be double-blind.
Missing values : The observations missing from the set of data for some of the reason. In longitudinal studies, for instance, they might occur because subjects drop out of the stud
The graphical process most frequently used in the analysis of data from a two-by-two crossover design. For each of the subject the difference between the response variable values o
Multicentre study : The clinical trial conducted simultaneously in the number of participating hospitals, with all centres following an agreed-upon study of the protocol and with
A standard IQ test has a mean of 98 and a standard deviation of 16. We want to be 99% certain that we are within 8 IQ points of the true mean. Determine the sample size
Non central distributions is the series of probability distributions each of which is the adaptation of one of the standard sampling distributions like the chi-squared distributio
Classification matrix: A term many times used in discriminant analysis for the matrix summarizing the results and outputs obtained from the derived classi?cation rule, and obtaine
The regression analysis is used to fit a model describing the relationship of a dependent variable with independent variable(s). Here we have fitted three regression models:
Matching distribution is a probability distribution which arises in the following manner. Suppose that the set of n subjects, numbered 1; . . . ; n respectively, are arranged in
Product-limit estimator is a method for estimating the survival functions for the set of survival times, some of which might be censored observations. The logic behind the procedu
Obuchowski and Rockette method is an alternative to the Dorfman-Berbaum-Metz technique for analyzing multiple reader receiver operating curve data. Instead of the modelling the ja
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