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Blinding: A procedure used in clinical trials to get rid of the possible bias which might be introduced if the patient and/or the doctor knew which treatment the patient is receiving. If neither the patient nor the doctor are aware of which treatment has been given the trial is known as double-blind. If only one out of the patient or doctor is unaware of the treatment, then the trial is called single-blind. Clinical trials should use maximum degree of blindness which is possible, even though in some areas, for instance, surgery, it is often not possible for an investigation to be double-blind.
Cohort study : An investigation in which the group of individuals (or the cohort) is identi?ed and followed prospectively, possibly for many years, and their subsequent medical his
The Current status data arise in the survival analysis if the observations are limited to the indicators of whether or not the event of interest has happened at the time the sample
Population pyramid : The diagram designed to show the comparison of the human population by sex and age at a given instant time, consisting of a pair of the histograms, one for eve
The probability distribution of the various observations is required to obtain the run of two successes in the series of Bernoulli trials with the probability of success equal to a
Non-randomized clinical trial is the clinical trial in which the series of consecutive patients receive a new treatment and those which respond (according to some of the pre-defin
One of the most exciting areas of mathematics involves the application of statistics to real-world settings to make informed decisions. In this task you will design, implement, and
The Null Hypothesis - H0: Model does not fit the data i.e. all slopes are equal to zero β 1 =β 2 =...=β k = 0 The Alternative Hypothesis - H1: Model does fit the data i.e. at
Compliance : The extent to which the participants in a clinical trial follow trial protocol, for instance, following both the intervention regimen and trial procedures (clinical vi
Product-limit estimator is a method for estimating the survival functions for the set of survival times, some of which might be censored observations. The logic behind the procedu
You may have the opportunity to buy some electronic components. These components may be reliable (1) or unreliable (2). The potential pro?ts are £10,000 if the components are rel
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