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Blinding: A procedure used in clinical trials to get rid of the possible bias which might be introduced if the patient and/or the doctor knew which treatment the patient is receiving. If neither the patient nor the doctor are aware of which treatment has been given the trial is known as double-blind. If only one out of the patient or doctor is unaware of the treatment, then the trial is called single-blind. Clinical trials should use maximum degree of blindness which is possible, even though in some areas, for instance, surgery, it is often not possible for an investigation to be double-blind.
Higher criticism is a multiple-comparison test concept arising from the situation where there are number of independent tests of significance and interest lies in the rejecting jo
The Null Hypothesis - H0: There is no heteroscedasticity i.e. β 1 = 0 The Alternative Hypothesis - H1: There is heteroscedasticity i.e. β 1 0 Reject H0 if Q = ESS/2 >
Nuisance parameter : The parameter of the model in which there is no scienti?c interest but whose values are generally required (but in usual are unknown) to make inferences about
A family of the probability distributions of the form given as here θ is the parameter and a, b, c, d are the known functions. It includes the gamma distribution, normal dis
Coincidences : Astonishing concurrence of the events, perceived as meaningfully related, with no apparent causal connection. Such type of events abounds in everyday life and is oft
Bioinformatics : Essentially the application of the information theory to biology to deal with the deluge of the information resulting from the advances in molecular biology. The m
The rapid development or growth of the disease in a community or region. Statistical thinking has made very much significant contributions to the understanding of such type of phen
A study not involving the passing of time. All information is collected at the same time and subjects are contacted only once. Many surveys are of this type. The temporal sequence
Back-projection: A term most often applied to the procedure for reconstructing plausible HIV incidence curves from the AIDS incidence data. The method or technique assumes that th
Institutional surveys are the surveys in which the primary sampling units are the institutions, for instance, hospitals. Within each of the sampled institution, a sample of the pa
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