Biosynthesis of hemes and chlorophylls, Biology

Assignment Help:

In animals, some of bacteria and fungi, and the first step in tetrapyrrole synthesis is the condensation of the amino acid glycine with succinyl  CoA (an intermediate  of the citric acid cycle) to built ALA (aminolaevulinic  acid).  This reaction is catalyzed by the enzyme ALA synthase that needed the coenzyme pyridoxal phosphate and is situated in the mitochondria of eukaryotes.  This committed phase in the pathway is subject to regulation.  Synthesis of the ALA synthase is feedback-inhibited by heme.  In algae, plants and various bacteria there is an alternative route for ALA synthesis which have the conversion of the intact five-carbon skeleton of glutamate in a series of three steps to yield ALA. In all organisms there are two molecules of ALA then condensing to form porphobilinogen in a reaction catalyzed by ALA dehydratase (also called as porphobilinogen synthase). Inhibition of this enzyme by lead is one of the main manifestations of acute lead poisoning.

 


Related Discussions:- Biosynthesis of hemes and chlorophylls

Factors affecting biotic potential - population growth, Factors Affecting B...

Factors Affecting Biotic Potential - Population Growth Biotic potential differs from one species to another e.g., bacterial populations can grow faster than population of oak

Explain about metabolic diseases, Q. Explain about Metabolic diseases? ...

Q. Explain about Metabolic diseases? Metabolic diseases, as you already know, refer to those disorders in which the various reactions in the cells are effected (production of e

Explain bidirectional glenn shunt under cardiopulmonary, Explain Bidirectio...

Explain Bidirectional Glenn Shunt under cardiopulmonary Bypass ? The ascending aorta and SVC at innominate jugular vein junction and IVC are cannulated and child connected to c

Apiculture, Apiculture : This is the study of bee-keeping for obtaining wax...

Apiculture : This is the study of bee-keeping for obtaining wax and honey.  Beekeeping is also known as apiculture, it is taken from Latin apis, bee. Apiculture is the maintenance

Illustrate the effect of the drugs, Which of the following is an effect of ...

Which of the following is an effect of the following drugs? A. Drug A is an agonist of the Vasopressin2 Receptor (V2R).  High levels of Drug A in the extracellular spaces surro

Phospholipids exhibit important biological functions, Phospholipids exhibi...

Phospholipids exhibit  important biological functions. They are: a)  increase  the rate of fatty acid oxidation b)  act as inorganic ion carrier across the membrane c) hel

.ecology, Name three sources of biofuel

Name three sources of biofuel

Classification scheme of protozoa, Classification Scheme of Protozoa ...

Classification Scheme of Protozoa Phylum Myxozoa Parasites of lower vertebrates especially fish and invertebrates. Phylum Microspora Parasites of inv

Explain process of fatty acid composition, Explain process of Fatty acid co...

Explain process of Fatty acid composition We know fats/oils are made up of fatty acids. The number, position and geometry of double bonds within the fatty acids affect the rate

Phylem porifera, please give us this phylem''s example...

please give us this phylem''s example...

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd