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In animals, some of bacteria and fungi, and the first step in tetrapyrrole synthesis is the condensation of the amino acid glycine with succinyl CoA (an intermediate of the citric acid cycle) to built ALA (aminolaevulinic acid). This reaction is catalyzed by the enzyme ALA synthase that needed the coenzyme pyridoxal phosphate and is situated in the mitochondria of eukaryotes. This committed phase in the pathway is subject to regulation. Synthesis of the ALA synthase is feedback-inhibited by heme. In algae, plants and various bacteria there is an alternative route for ALA synthesis which have the conversion of the intact five-carbon skeleton of glutamate in a series of three steps to yield ALA. In all organisms there are two molecules of ALA then condensing to form porphobilinogen in a reaction catalyzed by ALA dehydratase (also called as porphobilinogen synthase). Inhibition of this enzyme by lead is one of the main manifestations of acute lead poisoning.
What are the risk factors for the development of food allergy? Having gone through the discussion above, can you identify at least one important factor leading to food allergy?
Prevention of overloading the sterilizer Most sterilizers have a system to notify the operator of mechanical malfunction, but sterilizers cannot notify the operator whether the
important of biology to man
Growth Regulators Besides the major five hormones, polyamines can also exert regulatory control over growth and development at micromolar concentrations. They are widespread a
D-glucose differs from D-galactose only in the arrangement around carbon 4. Therefore D-glucose and D-galactose are- Select one: a. enantiomers b. epimers c. mirror ima
Describe Arteriovenous Continuous Murmur? Arteriovenous Continuous Murmur : These can be congenital as in coronary artery fistula entering RA/RV/PA, sinus of valsalva to rig
You are working with plants that have either hairy (dominant) or 'bald' (recessive) flowers. Hairy flowers have little hairs on them that make the flowers look fuzzy, bald flowers
Q. DNA damaged by alkylating agents? 1. Some simple alkylating agents 2. Illustrations of products of alkylating agents 3.Many of these products can be repaired by excision rep
What is the function of a control group in an experiment? The function of a control group in an experiment is to be a stable to account for any effects a given environment has
Blood Pump : Ideal Characteristics 1) I should be able to pump up to seven litres of blood per minute. 2) It should not damage cellular and cellular components of blo
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