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In animals, some of bacteria and fungi, and the first step in tetrapyrrole synthesis is the condensation of the amino acid glycine with succinyl CoA (an intermediate of the citric acid cycle) to built ALA (aminolaevulinic acid). This reaction is catalyzed by the enzyme ALA synthase that needed the coenzyme pyridoxal phosphate and is situated in the mitochondria of eukaryotes. This committed phase in the pathway is subject to regulation. Synthesis of the ALA synthase is feedback-inhibited by heme. In algae, plants and various bacteria there is an alternative route for ALA synthesis which have the conversion of the intact five-carbon skeleton of glutamate in a series of three steps to yield ALA. In all organisms there are two molecules of ALA then condensing to form porphobilinogen in a reaction catalyzed by ALA dehydratase (also called as porphobilinogen synthase). Inhibition of this enzyme by lead is one of the main manifestations of acute lead poisoning.
Define about the Population Dynamics? In this unit, we are going to study about human population who eventually suffer from these problems. Why do we want to study about human
2.?In order to increase muscular force production, muscular contractions may be modulated in two ways. Explain.
Define Sodium, Potassium and Chloride - Minerals? Claude Bernard was the first to draw attention to the internal environment (milieu interior), referring to the extracellular f
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Explain the Primary and Secondary air Pollutants a. Primary pollutants -emitted directly Particulate matter ( Sulfur dioxide (SO 2 ) Nitrogen dioxide (NO 2 )
Bacillary Dysentery: You have learnt about the diarrhoea in the foregoing sub-section, now let us take for example a child who has loose motion which contains blood and mucus
Enumerate the working of MRI scanner The MRI scanner can be 'tuned' to detect the very subtle disturbances to the magnetic field induced by the different proportions of oxygen
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Q. Concerning the thickness of their walls how different are the heart chambers? The ventricle walls are thicker than the atrium walls since ventricles are structures responsib
Which of the following functional groups does NOT contain a carbonyl? Select one: a. Aldehyde b. Carboxyl c. Phosphate d. Amide e. Organic ester
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