Bio physiology Matlab Simulink Models, Other Engineering

Assignment Help:

Review the lecture on BB document “Pharmacology …..” slide 6 where the solution for a 1st order system was demonstrated. The generic system is A(X)?(K1)?B(Y)?(K1’)?C(Z)



1. Create the A compartment (containing substance X) in SL and PROVE that when you start with a certain amount of X (the IC of an integrator) you get the expected result of X leaving the compartment exponentially. Label all axes and show the model with the blocks identified with appropriate labels. Submit the identified and labeled screen shot.

Reminder: To create a text box by double-clicking, and move by dragging the edge of the box.

2. Write the differential time dependent equations for the entire system of A?B?C with substances X, Y, and Z respectively. Submit the equations done neatly and in large text.

3. Now create the SIMULINK model for the ENTIRE system in 2 (above). Be sure to label lines and blocks with the variables or parts of the equation that are associated with the line or block. Make k1=k1’ - this is your initial, stable state). Submit a labeled screen shot of a RUN.

4. RUN the model in #3 with all 3 outputs: X(t), Y(t), Z(t) on ONE scope set to autoscale and label axes and each curve with X, Y, Z (with color coding). Submit a screen shot.

5. Now change k1 and k1’ to show the effect on Y, the B component. Do two different combinations of k1 and k1’ that CLEARLY show the effects on Y(t), the B component. Show a screen shot of each run. In doing this do as follows:
A. For EACH combination above, describe what you expect to happen to ALL 3 variables. Does the simulation verify your expectation?

B. Assume that Y(t) is an enzyme that participates significantly in manufacturing epinephrine. For EACH of the two conditions in 6A, describe what you expect will happen to heart rate AND blood pressure compared to the normal state.

HINT: If your ‘k’ value appears more than once in your model, be sure that you change all of them.

6. “Make it – Take it” (MI-TI) is a ubiquitous, omnipresent process in physiology and biochemistry. In a BRIEF 2 sentence statement, how does the simulation in #5 and #6 above demonstrate the MI-TI principle?

7. Given that the k and k’ rate values are enzyme-like steps, how would you use a drug to increase the B value (Y) by:
A. Manipulating k
B. Manipulating k’

Answer with ONE SENTENCE per question.

Related Discussions:- Bio physiology Matlab Simulink Models

Is the dividend paid on common stock taxable to shareholders, Is the divide...

Is the dividend paid on common stock taxable to shareholders? The results paid on common inventory are taxed on two stages in the U.S. First at the company stage, as a results c

Corporate finance., The firm is considering an investment opportunity. The ...

The firm is considering an investment opportunity. The investment falls in the same class of risk as the firm, the project is financed with equity and debt. Explain all the steps i

Energy bands, variation of energy bands with alloy composition

variation of energy bands with alloy composition

Core competencies that produce value, 1. What are the core competencies tha...

1. What are the core competencies that produce value? Answer: The core competencies of an organization which produce value are: i. Marketing: Every organization produces a product

LIBS, Laser induced breakdown spectroscopy

Laser induced breakdown spectroscopy

Zero-coupon bond, Zero-Coupon Bond is a type of bond gives no periodic inte...

Zero-Coupon Bond is a type of bond gives no periodic interest payments, instead is sold at a steep discount from its face value. Due to these bonds these do not pay interest until

Oil pumps, what is the function and location of the components?

what is the function and location of the components?

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd