Bio physiology Matlab Simulink Models, Other Engineering

Assignment Help:

Review the lecture on BB document “Pharmacology …..” slide 6 where the solution for a 1st order system was demonstrated. The generic system is A(X)?(K1)?B(Y)?(K1’)?C(Z)



1. Create the A compartment (containing substance X) in SL and PROVE that when you start with a certain amount of X (the IC of an integrator) you get the expected result of X leaving the compartment exponentially. Label all axes and show the model with the blocks identified with appropriate labels. Submit the identified and labeled screen shot.

Reminder: To create a text box by double-clicking, and move by dragging the edge of the box.

2. Write the differential time dependent equations for the entire system of A?B?C with substances X, Y, and Z respectively. Submit the equations done neatly and in large text.

3. Now create the SIMULINK model for the ENTIRE system in 2 (above). Be sure to label lines and blocks with the variables or parts of the equation that are associated with the line or block. Make k1=k1’ - this is your initial, stable state). Submit a labeled screen shot of a RUN.

4. RUN the model in #3 with all 3 outputs: X(t), Y(t), Z(t) on ONE scope set to autoscale and label axes and each curve with X, Y, Z (with color coding). Submit a screen shot.

5. Now change k1 and k1’ to show the effect on Y, the B component. Do two different combinations of k1 and k1’ that CLEARLY show the effects on Y(t), the B component. Show a screen shot of each run. In doing this do as follows:
A. For EACH combination above, describe what you expect to happen to ALL 3 variables. Does the simulation verify your expectation?

B. Assume that Y(t) is an enzyme that participates significantly in manufacturing epinephrine. For EACH of the two conditions in 6A, describe what you expect will happen to heart rate AND blood pressure compared to the normal state.

HINT: If your ‘k’ value appears more than once in your model, be sure that you change all of them.

6. “Make it – Take it” (MI-TI) is a ubiquitous, omnipresent process in physiology and biochemistry. In a BRIEF 2 sentence statement, how does the simulation in #5 and #6 above demonstrate the MI-TI principle?

7. Given that the k and k’ rate values are enzyme-like steps, how would you use a drug to increase the B value (Y) by:
A. Manipulating k
B. Manipulating k’

Answer with ONE SENTENCE per question.

Related Discussions:- Bio physiology Matlab Simulink Models

Blow hole and pin hole porosity, Difference between   Blow hole and pin hol...

Difference between   Blow hole and pin hole porosity          Blow hole : They appear as cavities in a casting. When they are visible on the upper surface of the castings, th

What is the difference between journal entry & ledger?, What is the differe...

What is the difference between JOURNAL ENTRY & LEDGER?  Journal is a journal of unique entrance. It is a journal where all the dealings of organization have been registered rela

4 bit comparator, process / description.. if I put A=1000 and B=0100 A>B ga...

process / description.. if I put A=1000 and B=0100 A>B gate will show output 1 and dose A

Capital budgeting, explain the objective of capital budgeting

explain the objective of capital budgeting

Rotating Equipment, #What are the types of pumps used in oil industry? How...

#What are the types of pumps used in oil industry? How to perform fault finding report?

Magnetic detector plug debris analysis of aircraft , Magnetic Detector Plug...

Magnetic Detector Plug Debris Analysis of aircraft : The magnetic chip detectors (MCDs), are small, permanent magnets installed in the scavenge/return lines of the engine oil s

Counter, Design a recycling MOD 19 up counter using JK FFs. In your design,...

Design a recycling MOD 19 up counter using JK FFs. In your design, include the logic circuit diagram and the timing diagram output that counts from 000002 = 010 to 100112 = 1910. C

Ts diagram, how to find points on Ts diagram?

how to find points on Ts diagram?

Line the crown of the tunnel, A 10m diameter circular tunnel is to be excav...

A 10m diameter circular tunnel is to be excavated in a jointed ground.  The joint sets spaced at 6m are dipping towards the West at 50°.  A horizontal circular tunnel is to be cons

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd