Are fibrates effective at lowering tg levels, Biology

Assignment Help:

Q. Are Fibrates effective at lowering TG levels?

Fibrates are effective at lowering TG levels by 20 per cent to 50 per cent and raising HDL by 10-35 per cent. LDL reduction varies with the agent used and may range from 5 per cent-20 per cent in patients who are not hypertriglyceridemic. Although a higher mortality rate was seen in the clofibrate arm of the World Health Organization study, such a finding was not seen in subsequent studies of gemfibrozil or bezafibrate. These agents have been demonstrated to impart reduction in risk of CAD events and are of use to treat mixed hyperlipidemia. Although these agents are often used in combination with statin therapy, there are no studies demonstrating reduction in clinical events with this approach. This combination increase the risk of myopathy. For patients with very high TG levels, fibrate therapy reduces the risk for pancreatitis.


Related Discussions:- Are fibrates effective at lowering tg levels

What are the properties of titanium, What are the Properties of titanium ...

What are the Properties of titanium Titanium has several favourable properties like low specific gravity with a density of 4.5 gm/cm 3 , high heat resistance and high strength

Kingdom animalia, critera for the animal classification

critera for the animal classification

Explain bond specificity, Bond specificity Some  enzymes  act  on  a pa...

Bond specificity Some  enzymes  act  on  a particular  bond  (glycosidic,  peptide,  ester  etc.). Examples:  pepsin,  trypsin,  chymotrypsin  etc. are  all  only  acting  on

Diversity, who is the farther of bio diversity?

who is the farther of bio diversity?

Methodology of environmental impact assessment, Environmental impact assess...

Environmental impact assessment consists of 4 phases which are as follows: (i)  Organizing the job. (ii)   Performing the assessment. (iii) Writing the environmental impac

Find equilibrium potential of a particular ion, Which of the following is N...

Which of the following is NOT required to determine equilibrium potential of a particular ion? Select one: size of the ion valence of the ion concentration gradient for

Tropical deciduous forests, Rainfall is high, sometimes higher than tropica...

Rainfall is high, sometimes higher than tropical rain forests but seasonal. There are pronounced wet and dry periods, and so are winter and summer seasons. The soils are brown in c

What is genotypical proportion of these gametes, Which is the kind of gamet...

Which is the kind of gamete (for a given trait) produced by a dominant homozygous individual? What is genotypical proportion of these gametes? And what about the recessive homozygo

Cultural and religious values, Wildlife has influenced language, art, relig...

Wildlife has influenced language, art, religion and social customs of many societies worldwide, and wild animals figure prominently in many cultures even today. In all cultures of

Explain the equilibrium dialysis, Explain the Equilibrium Dialysis? Equ...

Explain the Equilibrium Dialysis? Equilibrium dialysis is a useful technique for studying the binding of a small uncharged solute species (a ligand) to a macromolecule. The mac

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd