Anticoagulants, Biology

Assignment Help:

ANTICOAGULANTS

(a) Heparin (hepar = liver) . It is synthesized by mast cells of connective tissue and liver cells. It is a heteropolysaccharide. It increases the effectivity of antithrombin III (a - globulin) which inactivates the thrombin so prevents conversion of fibrinogen into fibrin.

(b) Hirudin. It is an anticoagulant present in the saliva of salivary glands of leech and is mixed with blood of host during its storage in its crop.

(c) Warfarin. It is an anticoagulant of plant origin, which when given to a patient, lowers the formation of prothrombin and factors VII, IX and X from liver cells by lowering the activity of Vitamin K.

(d) Sodium oxalate, sodium citrate and EDT A (Ethylene diamine tetra acetic acid) are used as anticoagulants in blood banks as these bind Ca++, so these are called chelating agents. .

(e) Chilling of blood also delays blood clotting as it lowers the activity of enzymes involved in blood clotting.

 

ROLE OF VITAMIN-K IN BLOOD CLOTTING -

Vitamin K, also called anti-haemorrhagic factor, is a fat soluble vitamin and is essential for the formation of prothrombin from the liver. Deficiency of vitamin K causes hypoprothrombinemia which interferes with blood clotting. Vitamin K is also synthesized by intestinal bacteria.


Related Discussions:- Anticoagulants

Define the term - sulphur, Define the term - Sulphur   Sulphur is found...

Define the term - Sulphur   Sulphur is found in small amounts in soil perhaps 0.15% only. A large part of sulphur used by plants comes from decomposing organic matter or from f

Explain point mutations gene, Explain Point Mutations gene? Mutations ...

Explain Point Mutations gene? Mutations involving single genes occur by addition, substitution, or deletion of a single base in DNA. Such mutations, called point mutations, ca

Explain the peptones - complex media, Explain the Peptones - Complex Media?...

Explain the Peptones - Complex Media? Peptones are protein hydrolysates obtained by partial digestion of meat, casein, soya meal, gelatin or other protein source. These provide

Derive gorlin formula, Q. Derive Gorlin Formula? Formula I: First Hydra...

Q. Derive Gorlin Formula? Formula I: First Hydraulic Formula (Toricelli's law) F = AVCc Where, F = flow rate A = orifice area Cc = coefficient of orifice cont

Mortality - population parameters and regulation, Mortality - Population Pa...

Mortality - Population Parameters and Regulation The death of an individual in a population is known as mortality. Mortality rate like natality rate can be expressed as the nu

Descriptions of the genera, Q. Descriptions of the genera? A manual is ...

Q. Descriptions of the genera? A manual is a book that contains information on the area of coverage and keys and descriptions of the families, genera and species including the

Pomology, Pomology :  This is the study of fruits and fruit yielding plants...

Pomology :  This is the study of fruits and fruit yielding plants of commercial importance.  Pomology is a branch of botany which studies or cultivates pome fruit, and particularly

Special situations of pulmonary embolism, Q. Special situations of Pulmonar...

Q. Special situations of Pulmonary Embolism? The CXR is often abnormal in pulmonary embolism. Atelectasis and other focal pulmonary parenchymal abnormalities are the most commo

Ideal eia and measures and benefits of eia, An ideal EIA system would: ...

An ideal EIA system would: (i)     Apply to all projects that are expected to have significant environmental effects and address all impacts that are expected to occur due to t

Explain cooperative behaviours of social animal group, Explain Cooperative ...

Explain Cooperative behaviours of social animal group Group living, specialist roles, eg bees, ants Altruism, eg social insects, meerkats Group defence, eg social

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd