Anticoagulants, Biology

Assignment Help:

ANTICOAGULANTS

(a) Heparin (hepar = liver) . It is synthesized by mast cells of connective tissue and liver cells. It is a heteropolysaccharide. It increases the effectivity of antithrombin III (a - globulin) which inactivates the thrombin so prevents conversion of fibrinogen into fibrin.

(b) Hirudin. It is an anticoagulant present in the saliva of salivary glands of leech and is mixed with blood of host during its storage in its crop.

(c) Warfarin. It is an anticoagulant of plant origin, which when given to a patient, lowers the formation of prothrombin and factors VII, IX and X from liver cells by lowering the activity of Vitamin K.

(d) Sodium oxalate, sodium citrate and EDT A (Ethylene diamine tetra acetic acid) are used as anticoagulants in blood banks as these bind Ca++, so these are called chelating agents. .

(e) Chilling of blood also delays blood clotting as it lowers the activity of enzymes involved in blood clotting.

 

ROLE OF VITAMIN-K IN BLOOD CLOTTING -

Vitamin K, also called anti-haemorrhagic factor, is a fat soluble vitamin and is essential for the formation of prothrombin from the liver. Deficiency of vitamin K causes hypoprothrombinemia which interferes with blood clotting. Vitamin K is also synthesized by intestinal bacteria.


Related Discussions:- Anticoagulants

Describe the impact and burden of heart diseases, Describe the IMPACT AND B...

Describe the IMPACT AND BURDEN OF HEART DISEASES ? No discussion on the epidemiology of heart diseases will be complete without a look at the tremendous burden put by different

Explain water and electrolyte imbalance during kwashiorkor, Explain Water a...

Explain Water and electrolyte imbalance during kwashiorkor? The total body water and especially the extracellular fluid volume are increased in all forms of PEM. At the same ti

Find out pathway information about the proteins, Biopathways 1. Find out...

Biopathways 1. Find out pathway information about these proteins using the Human Reactome. O00327 O14503 O75586 O95096 P01137 P01308 P06744 P08240 P12

Sp and spp., what is the deference between sp. and spp.?

what is the deference between sp. and spp.?

Explain the neuritic type of infantile beriberi, Explain the neuritic type ...

Explain the neuritic type of infantile beriberi? It is also referred to as Wernicke korsakoff syndrome or cerebral beriberi. It shows typical manifestations of peripheral neuro

Nutritional deficiency, Iron deficiency should be treated with supplemental...

Iron deficiency should be treated with supplemental iron. • Osteoporosis should be treated with calcium and vitamin D supplements. • Depending on individual factors, patien

What is atom, What is atom? Atoms are the smallest component of matter ...

What is atom? Atoms are the smallest component of matter that determine its unique chemical and physical properties. They are composed of negatively charged electrons, positive

A monohybrid cross, A monohybrid cross: A.Determines the genetic makeup of ...

A monohybrid cross: A.Determines the genetic makeup of an organism B.always involves homozygous alleles. C.always involves organisms that are heterozygous at all loci. D.Always inv

Planting bacteria gardens, Planting bacteria gardens When the bacteria ...

Planting bacteria gardens When the bacteria gardens have cooled place them out on the table but do not increase the glass covers unless you are ready to plant them. Toothpicks

5, Air Microbes

Air Microbes

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd