Anticoagulants, Biology

Assignment Help:

ANTICOAGULANTS

(a) Heparin (hepar = liver) . It is synthesized by mast cells of connective tissue and liver cells. It is a heteropolysaccharide. It increases the effectivity of antithrombin III (a - globulin) which inactivates the thrombin so prevents conversion of fibrinogen into fibrin.

(b) Hirudin. It is an anticoagulant present in the saliva of salivary glands of leech and is mixed with blood of host during its storage in its crop.

(c) Warfarin. It is an anticoagulant of plant origin, which when given to a patient, lowers the formation of prothrombin and factors VII, IX and X from liver cells by lowering the activity of Vitamin K.

(d) Sodium oxalate, sodium citrate and EDT A (Ethylene diamine tetra acetic acid) are used as anticoagulants in blood banks as these bind Ca++, so these are called chelating agents. .

(e) Chilling of blood also delays blood clotting as it lowers the activity of enzymes involved in blood clotting.

 

ROLE OF VITAMIN-K IN BLOOD CLOTTING -

Vitamin K, also called anti-haemorrhagic factor, is a fat soluble vitamin and is essential for the formation of prothrombin from the liver. Deficiency of vitamin K causes hypoprothrombinemia which interferes with blood clotting. Vitamin K is also synthesized by intestinal bacteria.


Related Discussions:- Anticoagulants

Research and documentation - conservation of wildlife, Research and Documen...

Research and Documentation - Conservation of wildlife First, list of endangered species are established by various national and international agencies. Another important actio

Define effect on oestrogens and progesterone in pregnancy, Define effect on...

Define effect on Oestrogens and progesterone in pregnancy? Oestrogens and progesterone are secreted by the placenta from 8-10 weeks of gestation. Progesterone increases through

Explain the population growth of ecology, Explain the Population Growth? ...

Explain the Population Growth? A population can grow, it can remain stable, or it can decrease in size. Measuring the size of a population over time is used to help determine t

Define precipitation or solubility of proteins, Define Precipitation or Sol...

Define Precipitation or Solubility of Proteins? Most of the functional properties are dependent on the degree to which the proteins are soluble. The solubility behaviour provid

Define biodiversity and ecosystem stability, Define Biodiversity and ecosys...

Define Biodiversity and ecosystem stability? Human's have transformed ecosystems all through the world, frequently replacing diverse natural ecosystems with ecosystems which ar

Explain phylum ciliophora, Phylum Ciliophora 1) They have cilia at some...

Phylum Ciliophora 1) They have cilia at some stage in the life-cycle. The cilia are used for locomotion or creating a feeding current. 2) They feed heterotrophically usually

Explain microbiology of water, Q. Explain microbiology of water? Ans. ...

Q. Explain microbiology of water? Ans. Unlike air, natural waters contain their natural flora, as well as, microorganisms from soil and possibly from animals and se

Parathyroid gland, PARATHYRIOD GLANDS - They develop from the endode...

PARATHYRIOD GLANDS - They develop from the endoderm of the embryo. The parathyroid glands consist of four separate glands located on the posterior surface of the lobes of

Heparin, HE P ARIN It is highly sulphated mucopolysaccharide made ...

HE P ARIN It is highly sulphated mucopolysaccharide made of alternate units of glucosamine and glucuronic acid. Heparin is mainly produced by liver and mast cells. I

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd