Anticoagulants, Biology

Assignment Help:

ANTICOAGULANTS

(a) Heparin (hepar = liver) . It is synthesized by mast cells of connective tissue and liver cells. It is a heteropolysaccharide. It increases the effectivity of antithrombin III (a - globulin) which inactivates the thrombin so prevents conversion of fibrinogen into fibrin.

(b) Hirudin. It is an anticoagulant present in the saliva of salivary glands of leech and is mixed with blood of host during its storage in its crop.

(c) Warfarin. It is an anticoagulant of plant origin, which when given to a patient, lowers the formation of prothrombin and factors VII, IX and X from liver cells by lowering the activity of Vitamin K.

(d) Sodium oxalate, sodium citrate and EDT A (Ethylene diamine tetra acetic acid) are used as anticoagulants in blood banks as these bind Ca++, so these are called chelating agents. .

(e) Chilling of blood also delays blood clotting as it lowers the activity of enzymes involved in blood clotting.

 

ROLE OF VITAMIN-K IN BLOOD CLOTTING -

Vitamin K, also called anti-haemorrhagic factor, is a fat soluble vitamin and is essential for the formation of prothrombin from the liver. Deficiency of vitamin K causes hypoprothrombinemia which interferes with blood clotting. Vitamin K is also synthesized by intestinal bacteria.


Related Discussions:- Anticoagulants

What are the characteristics of thick gingiva, Characteristics of Thick Gin...

Characteristics of Thick Gingiva  Relatively flat soft tissue and bony architecture  Dense fibrotic soft tissue  Relatively large amount of attached gingiva  Thick und

Explain systemic circulation in human biology, Explain Systemic Circulation...

Explain Systemic Circulation in human biology? In systemic circulation, oxygenated blood is pumped from the left atrium through the bicuspid valve, into the left ventricle, and

Biomedical application using a microcontroller, Search the web (mainly IEEE...

Search the web (mainly IEEE and ACM) publication databases to find a recent article on a biomedical application using a microcontroller. Clearly cite your reference(s). In your

What is malabsorption syndrome, Q. What is Malabsorption Syndrome? Did ...

Q. What is Malabsorption Syndrome? Did you know that a major part of the absorption of nutrients takes place in the small intestine and the set of enzymes involved in this proc

Bacterial diseases-botulism, Botulism Botulism is a rapidly fatal motor...

Botulism Botulism is a rapidly fatal motor paralysis. It is caused by ingestion of toxin of Clostridium botulinum in food. Many species of domesticated, wild animals and birds

Flying fish pisces, the characteristics of flying fish belong to pisces

the characteristics of flying fish belong to pisces

Closed style - style of stigma interaction, Closed Style - Style of Stigma ...

Closed Style - Style of Stigma Interaction Cotton shows an epidermis with stomata, a cortex of thin-walled parenchyma with several vascular bundles and strands of transmitting

Which are the main cells of the nervous system, Which are the main cells of...

Which are the main cells of the nervous system? The major cells of the nervous system are the neurons. Besides the neurons the nervous system is also constituted of glial cells

How many times acidic is a ph=4, How many times more acidic is a pH=4 from ...

How many times more acidic is a pH=4 from a pH=7 solution?

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd