Anticoagulants, Biology

Assignment Help:

ANTICOAGULANTS

(a) Heparin (hepar = liver) . It is synthesized by mast cells of connective tissue and liver cells. It is a heteropolysaccharide. It increases the effectivity of antithrombin III (a - globulin) which inactivates the thrombin so prevents conversion of fibrinogen into fibrin.

(b) Hirudin. It is an anticoagulant present in the saliva of salivary glands of leech and is mixed with blood of host during its storage in its crop.

(c) Warfarin. It is an anticoagulant of plant origin, which when given to a patient, lowers the formation of prothrombin and factors VII, IX and X from liver cells by lowering the activity of Vitamin K.

(d) Sodium oxalate, sodium citrate and EDT A (Ethylene diamine tetra acetic acid) are used as anticoagulants in blood banks as these bind Ca++, so these are called chelating agents. .

(e) Chilling of blood also delays blood clotting as it lowers the activity of enzymes involved in blood clotting.

 

ROLE OF VITAMIN-K IN BLOOD CLOTTING -

Vitamin K, also called anti-haemorrhagic factor, is a fat soluble vitamin and is essential for the formation of prothrombin from the liver. Deficiency of vitamin K causes hypoprothrombinemia which interferes with blood clotting. Vitamin K is also synthesized by intestinal bacteria.


Related Discussions:- Anticoagulants

Define some precautions for estimation of amount of bacteria, Define some P...

Define some Precautions for Estimation of the Amount of Bacteria? 1. Dilution should be made carefully. 2. Use fresh sterile pipette for making each dilution. 3. Aseptic

Active Transport, How does the addition of a watery secretion to the conten...

How does the addition of a watery secretion to the contents of the gut help in the process of digestion?

What is the concentration of your new solution, You have 30 mL of a 1M sodi...

You have 30 mL of a 1M sodium monophosphate buffer and you dilute dilute it to a volume of 10L. What is the concentration of your new solution? I came up with 0.003M, does that see

Difference between the concepts of food chain and food web, What is the dif...

What is the difference between the concepts of food chain and food web? The chain theory is a theoretical model to study the energy flux in ecosystems. In fact, in an ecosystem

Renal function & cardiovascular - change related with ageing, Define Renal ...

Define Renal Function & cardiovascular - change related with ageing? Changes associated with the cardiovascular and renal function: The progressive accumulation of athermanous

What are transcription process and the replication processes, Q What are th...

Q What are the differences and similarities between the transcription process and the replication processes? A DNA polynucleotide chain serves up as a template in the replication (

Hypothalamus gland, HYPOTHALAMUS - Hypothalamus develops from the ectod...

HYPOTHALAMUS - Hypothalamus develops from the ectoderm of the embryo. Location and Structure. It lies below or inferior to the thalamus. The hypothalamus is connected to t

Kinds of ovules, Kinds of Ovules Ovules undergo varied degrees of cur...

Kinds of Ovules Ovules undergo varied degrees of curvature during development. The position of micropyle with respect to the funiculus becomes different and constitutes the b

Explain the ps in vcd in cyanotic heart disease, Explain the PS In VCD in C...

Explain the PS In VCD in Cyanotic Heart Disease ? These are peculiar to this group only. It occurs in young infants (usually after two months and rarely after two years), It co

What is harmonious ecological interaction, Q. What is inharmonious ecologic...

Q. What is inharmonious ecological interaction? The negative or Inharmonious ecological interaction is that in which at least one of the participating beings is harmed. Q.

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd