Anticoagulants, Biology

Assignment Help:

ANTICOAGULANTS

(a) Heparin (hepar = liver) . It is synthesized by mast cells of connective tissue and liver cells. It is a heteropolysaccharide. It increases the effectivity of antithrombin III (a - globulin) which inactivates the thrombin so prevents conversion of fibrinogen into fibrin.

(b) Hirudin. It is an anticoagulant present in the saliva of salivary glands of leech and is mixed with blood of host during its storage in its crop.

(c) Warfarin. It is an anticoagulant of plant origin, which when given to a patient, lowers the formation of prothrombin and factors VII, IX and X from liver cells by lowering the activity of Vitamin K.

(d) Sodium oxalate, sodium citrate and EDT A (Ethylene diamine tetra acetic acid) are used as anticoagulants in blood banks as these bind Ca++, so these are called chelating agents. .

(e) Chilling of blood also delays blood clotting as it lowers the activity of enzymes involved in blood clotting.

 

ROLE OF VITAMIN-K IN BLOOD CLOTTING -

Vitamin K, also called anti-haemorrhagic factor, is a fat soluble vitamin and is essential for the formation of prothrombin from the liver. Deficiency of vitamin K causes hypoprothrombinemia which interferes with blood clotting. Vitamin K is also synthesized by intestinal bacteria.


Related Discussions:- Anticoagulants

Deficiency diseases-pregnancy toxaemia in sheep , Pregnancy toxaemia in she...

Pregnancy toxaemia in sheep (twin lamb disease, sleeping ewes disease, pregnancy ketosis). Pregnancy toxaemia is a multifactor disorder of energy metabolism affecting sheep du

Peptide bond, PEPTID E BOND Peptide or amide bond is a linkage es...

PEPTID E BOND Peptide or amide bond is a linkage established condensation reaction between amino group of one amino acid and carboxylic group of the second amino acid.

Why alkaline phosphatases use water as a second substrate, Alkaline Phospha...

Alkaline Phosphatases use water as a second substrate. Why do we still treat their kinetics as if they were for a single-substrate reaction?

Describe the phylum chordata in animal kingdom, Describe the Phylum Chordat...

Describe the Phylum Chordata in animal kingdom? This is the other group of animals along with the Echinodermata whose anus develops prior to the mouth's development in the embr

Extravascular compression, Most of the coronary blood flow to the left vent...

Most of the coronary blood flow to the left ventricular myocardium occurs during diastole. Thus the contracting heart obstructs its own blood supply. The systolic compressive force

Can you explain cholera, Q. Can you explain Cholera? Cholera is one of ...

Q. Can you explain Cholera? Cholera is one of the diseases which had caused epidemics all over the world. The organism which causes the disease is Vibrio cholerae. It is an

Signs and symptoms and treatments of hepatitis c, Q. What are the modes of ...

Q. What are the modes of transmission, main signs and symptoms and treatments of hepatitis C? The Hepatitis C is caused by the RNA virus and transmitted through blood (like hep

TAKHTAJANS classification, comparison between takhtajans and natural classi...

comparison between takhtajans and natural classification

What is mendels second law, What is Mendel's second law? Mendel's seco...

What is Mendel's second law? Mendel's second law postulates that two or more different traits are also conditioned by two or more pair of dissimilar factors and that each inhe

Main opportunistic diseases that can affect aids patients, Q. What are the ...

Q. What are the main opportunistic diseases that can affect AIDS patients? Among the opportunistic diseases that affect HIV contaminated people during the AIDS stage some are:

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd