Anticoagulants, Biology

Assignment Help:

ANTICOAGULANTS

(a) Heparin (hepar = liver) . It is synthesized by mast cells of connective tissue and liver cells. It is a heteropolysaccharide. It increases the effectivity of antithrombin III (a - globulin) which inactivates the thrombin so prevents conversion of fibrinogen into fibrin.

(b) Hirudin. It is an anticoagulant present in the saliva of salivary glands of leech and is mixed with blood of host during its storage in its crop.

(c) Warfarin. It is an anticoagulant of plant origin, which when given to a patient, lowers the formation of prothrombin and factors VII, IX and X from liver cells by lowering the activity of Vitamin K.

(d) Sodium oxalate, sodium citrate and EDT A (Ethylene diamine tetra acetic acid) are used as anticoagulants in blood banks as these bind Ca++, so these are called chelating agents. .

(e) Chilling of blood also delays blood clotting as it lowers the activity of enzymes involved in blood clotting.

 

ROLE OF VITAMIN-K IN BLOOD CLOTTING -

Vitamin K, also called anti-haemorrhagic factor, is a fat soluble vitamin and is essential for the formation of prothrombin from the liver. Deficiency of vitamin K causes hypoprothrombinemia which interferes with blood clotting. Vitamin K is also synthesized by intestinal bacteria.


Related Discussions:- Anticoagulants

Formation and role of hypoblast, Formation and Role of Hypoblast Hypo...

Formation and Role of Hypoblast Hypoblast is made as a result of two processes. First, some cells individually leave the blastoderm and move down via poly invagination into t

How do antibody-based tests detect how hiv infection work, Q. How do antibo...

Q. How do antibody-based tests detect how HIV infection works? Subsequent to the infection by the HIV the immune system begins the production of antibodies (primary immune resp

Define role of nutrients in controlling gene expression, Define Role of Nut...

Define Role of Nutrients in Controlling Gene Expression? The role of several nutrients in controlling gene expression, as mentioned earlier, is in infancy, but with advancing b

Fiehes test and aniline chloride test, Q. Fiehes test and Aniline chloride ...

Q. Fiehes test and Aniline chloride test? Determine the adulteration in the given honey sample by Fiehe's test and Aniline chloride test This activity will help you to: •

Planning and implementing nursing care - acute renal failure, Planning the ...

Planning the Nursing Care Monitor fluid intake and urinary output  Administer drugs as advised/prescribed  Monitor the child on dialysis  Provide therapeutic diet

Give an introduction to intensive care, Give an introduction to intensive c...

Give an introduction to intensive care ? Intensive Care Medicine has its origins from the polio epidemic of 1952 in Copenhagen. Patients who suffered respiratory paralysis were

Advances in mineral and vitamin nutrition of livestock, Advances in Mineral...

Advances in Mineral and Vitamin Nutrition of Livestock Even though, minerals and vitamins as nutrients are as essential as energy and protein, general negligence occurs primari

Agrostology, Agrostology : This is related to all types of grasses. Agrosto...

Agrostology : This is related to all types of grasses. Agrostology is sometimes called as graminology. Agrostology is the scientific study of grasses. It typically encompasses the

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd