Anticoagulants, Biology

Assignment Help:

ANTICOAGULANTS

(a) Heparin (hepar = liver) . It is synthesized by mast cells of connective tissue and liver cells. It is a heteropolysaccharide. It increases the effectivity of antithrombin III (a - globulin) which inactivates the thrombin so prevents conversion of fibrinogen into fibrin.

(b) Hirudin. It is an anticoagulant present in the saliva of salivary glands of leech and is mixed with blood of host during its storage in its crop.

(c) Warfarin. It is an anticoagulant of plant origin, which when given to a patient, lowers the formation of prothrombin and factors VII, IX and X from liver cells by lowering the activity of Vitamin K.

(d) Sodium oxalate, sodium citrate and EDT A (Ethylene diamine tetra acetic acid) are used as anticoagulants in blood banks as these bind Ca++, so these are called chelating agents. .

(e) Chilling of blood also delays blood clotting as it lowers the activity of enzymes involved in blood clotting.

 

ROLE OF VITAMIN-K IN BLOOD CLOTTING -

Vitamin K, also called anti-haemorrhagic factor, is a fat soluble vitamin and is essential for the formation of prothrombin from the liver. Deficiency of vitamin K causes hypoprothrombinemia which interferes with blood clotting. Vitamin K is also synthesized by intestinal bacteria.


Related Discussions:- Anticoagulants

Pathogenesis of acute rheumatic fever, You have learnt about the epidemiolo...

You have learnt about the epidemiology, etiology and pathogenesis of acute rheumatic fever. Revised Jones criteria, which have major and minor criteria, are helping to diagnosis of

Assuming the equilibrium potential for sodium ion, Assuming that the equili...

Assuming that the equilibrium potential for sodium ion across a skeletal muscle is +66 mv at a temperature of 37 degree celcius when the external concentration is 145 mM and the in

Determine the classification of colloidal systems, Classification of Colloi...

Classification of Colloidal Systems Thomas Graham referred to colloids as  the study of sub microscope dispersion. According to him, it dealt with the dispersed systems of a de

Biophysics, you are setting up a pcr reaction to amplify a 1000 basepair lo...

you are setting up a pcr reaction to amplify a 1000 basepair long dna grament. in your 50 microliter reaction volume you have 100 nanogrM OD RWMPLrw sn QIRH eoufly 50/50 at/gc 100

Explain types known in metabolic pathways, How many regulatory enzyme types...

How many regulatory enzyme types known in metabolic pathways, explain in detail by giving examples.

What is the difference between macro and micronutrients, What is the differ...

What is the difference between macro and micronutrients? The categorization criterion of nutrients into macro and micronutrients has no relation to the size of the molecule. M

Name the rich source of aerobic bacteria, 1. Biogas is produced by the acti...

1. Biogas is produced by the activity of aerobic bacteria on animal waste 2. Methanobacterium is an aerobic bacterium found in rumen of cattle 3. Biogas, commonly called goba

Inhalation route for injection, Inhalation Route for Injection Therapi...

Inhalation Route for Injection Therapies that can be administered by inhalation are oxygen, humidification-cool mist and steam, administering local medication. The commonly u

Stage of total biological inactivity, Q. Is the stage when an insect larva ...

Q. Is the stage when an insect larva is within a cocoon a stage of total biological inactivity? The period when the larva is inside its cocoon is a time of intense biological a

Assessment and management of aortic stenosis, Assessment   The severity...

Assessment   The severity of symptoms depend on degree of obstruction.  In case of severe obstruction,  ECG shows right ventricular or biventricular hypertrophy. Cardiac cathet

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd