Anticoagulants, Biology

Assignment Help:

ANTICOAGULANTS

(a) Heparin (hepar = liver) . It is synthesized by mast cells of connective tissue and liver cells. It is a heteropolysaccharide. It increases the effectivity of antithrombin III (a - globulin) which inactivates the thrombin so prevents conversion of fibrinogen into fibrin.

(b) Hirudin. It is an anticoagulant present in the saliva of salivary glands of leech and is mixed with blood of host during its storage in its crop.

(c) Warfarin. It is an anticoagulant of plant origin, which when given to a patient, lowers the formation of prothrombin and factors VII, IX and X from liver cells by lowering the activity of Vitamin K.

(d) Sodium oxalate, sodium citrate and EDT A (Ethylene diamine tetra acetic acid) are used as anticoagulants in blood banks as these bind Ca++, so these are called chelating agents. .

(e) Chilling of blood also delays blood clotting as it lowers the activity of enzymes involved in blood clotting.

 

ROLE OF VITAMIN-K IN BLOOD CLOTTING -

Vitamin K, also called anti-haemorrhagic factor, is a fat soluble vitamin and is essential for the formation of prothrombin from the liver. Deficiency of vitamin K causes hypoprothrombinemia which interferes with blood clotting. Vitamin K is also synthesized by intestinal bacteria.


Related Discussions:- Anticoagulants

Explain why the plasmid is described as a vector, Humans produce insulin fr...

Humans produce insulin from certain cells in the pancreas.The insulin gene is isolated from a human pancreas cell and then inserted into a plasmid.The DNA responsible for the synth

What is the inner life of the genome, For the article entitled "The inner l...

For the article entitled "The inner life of the genome" which of the following is true? A. Individual chromosomes occupy explained territories within the nucleus. B. The spe

Classification based on digestive fate of carbohydrates, Explain Classifica...

Explain Classification Based on Digestive Fate of Carbohydrates? The digestive fate of carbohydrates depends on their inherent chemical nature (monosaccharide composition and t

Explain resistance to infection in nutritional care, Explain Resistance to ...

Explain Resistance to Infection in Nutritional Care? Amino acids help to build the body's defence mechanisms like antibodies, blood cells, hormones and enzymes so as to prevent

Classification of agro-industrial byproducts, Classification of agro-indust...

Classification of agro-industrial byproducts Based on their nutrient content agro-industrial byproducts can be divided into: 1.  Feed low in fiber and low in protein. These ar

Temperature affecting the growth of microorganism, Temperature is one of th...

Temperature is one of the important factors affecting the process of growth in bacteria, as it has a bearing on chemical reactions. The temperature at which the maximum growth occu

Descriibe mechanical ventilation and cardiac performance, Descriibe Mechani...

Descriibe Mechanical Ventilation and Cardiac Performance During spontaneous breathing, the intrathoracic and intrapulmonary pressures are negative, while with mechanical venti

Clinical features - infective endocarditis, The clinical  manifestations of...

The clinical  manifestations of IE result from the local destructive effects of intracardiac infection; the embolization of bland or septic fragments of vegetations to

How can nutrients are classified, According to their functions how can nutr...

According to their functions how can nutrients are classified? One possible and utile functional classification for nutrients is the one that divides them into energetic, struc

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd