Anticoagulants, Biology

Assignment Help:

ANTICOAGULANTS

(a) Heparin (hepar = liver) . It is synthesized by mast cells of connective tissue and liver cells. It is a heteropolysaccharide. It increases the effectivity of antithrombin III (a - globulin) which inactivates the thrombin so prevents conversion of fibrinogen into fibrin.

(b) Hirudin. It is an anticoagulant present in the saliva of salivary glands of leech and is mixed with blood of host during its storage in its crop.

(c) Warfarin. It is an anticoagulant of plant origin, which when given to a patient, lowers the formation of prothrombin and factors VII, IX and X from liver cells by lowering the activity of Vitamin K.

(d) Sodium oxalate, sodium citrate and EDT A (Ethylene diamine tetra acetic acid) are used as anticoagulants in blood banks as these bind Ca++, so these are called chelating agents. .

(e) Chilling of blood also delays blood clotting as it lowers the activity of enzymes involved in blood clotting.

 

ROLE OF VITAMIN-K IN BLOOD CLOTTING -

Vitamin K, also called anti-haemorrhagic factor, is a fat soluble vitamin and is essential for the formation of prothrombin from the liver. Deficiency of vitamin K causes hypoprothrombinemia which interferes with blood clotting. Vitamin K is also synthesized by intestinal bacteria.


Related Discussions:- Anticoagulants

Pericardial valves: carpentier edwards, Pericardial Valves: Carpentier Edwa...

Pericardial Valves: Carpentier Edwards (Perimount Valve) :  Pericardium preserved in gluteraldehyde and mounted on flexible stent is available for mitral and aortic positions

Explain about gamma diversity, Q. Explain about gamma diversity? Gamma ...

Q. Explain about gamma diversity? Gamma (g) richness refers to the rate of change across larger landscape gradients and gamma diversity is a measure of the overall diversity fo

Describe the maturity stages in fish, Question 1: (a) Describe the mat...

Question 1: (a) Describe the maturity stages in fish. (b) "k" and "r" selection strategies are commonly used to describe the response of fish to biotic and abiotic cond

Biology - a science of exception, BIOLOGY - A SCIENCE OF EXCEPTION - So...

BIOLOGY - A SCIENCE OF EXCEPTION - Some common examples to prove it are - 1.       Embryos of dicot plants have 2 cotyledons but in cuscuta (Dodder plant or amer bel or Aka

Entropy, ENTROP Y - Transfer of energy takes place from high energy...

ENTROP Y - Transfer of energy takes place from high energy level to low energy level. Rudol f clausius gave this term. During it there is collision of particles, r

Exon, Exon are those parts of a genomic DNA sequence which will be represe...

Exon are those parts of a genomic DNA sequence which will be represented in final, mature mRNA t A contiguous segment of the genomic DNA which codes for a polypeptide in the gene.

Radiographic evaluation - criteria for endosteal implants, Radiographic Eva...

Radiographic Evaluation - criteria for endosteal implants Surgical and interventional imaging involves imaging the patient  during and immediately after surgery and during the

The halstead-reitan neuropsychological battery, The halstead-reitan neurops...

The halstead-reitan neuropsychological battery The beginnings of the battery can be traced to the special laboratory established by Halstead in 1935 for the study of neurosurgi

Self- vs. cross-pollination, Self- vs. Cross-Pollination A major adva...

Self- vs. Cross-Pollination A major advantage of self-pollination is its certainty. Continued self-pollination over many generations, however, results in weaker progeny. This

Illustrate about urine of humans, Urine Normal urine is clear, yellow i...

Urine Normal urine is clear, yellow in colour, slightly acidic. Urine consists of 96% water and 4% solids like urea, uric acid, urates, chlorides, phosphates, oxalates, sulphat

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd