Anticoagulants, Biology

Assignment Help:

ANTICOAGULANTS

(a) Heparin (hepar = liver) . It is synthesized by mast cells of connective tissue and liver cells. It is a heteropolysaccharide. It increases the effectivity of antithrombin III (a - globulin) which inactivates the thrombin so prevents conversion of fibrinogen into fibrin.

(b) Hirudin. It is an anticoagulant present in the saliva of salivary glands of leech and is mixed with blood of host during its storage in its crop.

(c) Warfarin. It is an anticoagulant of plant origin, which when given to a patient, lowers the formation of prothrombin and factors VII, IX and X from liver cells by lowering the activity of Vitamin K.

(d) Sodium oxalate, sodium citrate and EDT A (Ethylene diamine tetra acetic acid) are used as anticoagulants in blood banks as these bind Ca++, so these are called chelating agents. .

(e) Chilling of blood also delays blood clotting as it lowers the activity of enzymes involved in blood clotting.

 

ROLE OF VITAMIN-K IN BLOOD CLOTTING -

Vitamin K, also called anti-haemorrhagic factor, is a fat soluble vitamin and is essential for the formation of prothrombin from the liver. Deficiency of vitamin K causes hypoprothrombinemia which interferes with blood clotting. Vitamin K is also synthesized by intestinal bacteria.


Related Discussions:- Anticoagulants

Bty100, 1. (a) Which physicochemical properties need to be regulated by the...

1. (a) Which physicochemical properties need to be regulated by the cell? Define chemical equilibrium and discuss how it is maintained by the cell. (b) Differentiate between facili

What is meant by suction force of the plant cell, What is meant by suction ...

What is meant by suction force of the plant cell? Does the suction force facilitate or make difficult the entrance of water into the cell? As the vacuolar solution is hypertoni

How do placental mammals reproduce, How do placental mammals reproduce? ...

How do placental mammals reproduce? Placental mammals reproduce sexually, they have internal fecundation and they are viviparous, i.e., their embryo creates within the mother's

Gene organization, In marked contrast to prokaryotic genes where proteins a...

In marked contrast to prokaryotic genes where proteins are encoded by a continuous sequence of triplet codons and the vast popular of protein-coding genes in eukaryotes are discont

What is the principle of the design, In designing an experiment to find out...

In designing an experiment to find out whether light is required for photosynthesis    (a) what is the principle of the design    (b) what control would you use?

Give the introduction of genesis of coronary artery diseases, Give the intr...

Give the introduction of genesis of coronary artery diseases and risk factors? Cardio-vascular diseases have their roots in the structure and functional alterations in the vasc

Proteins of plant origin - vegetable proteins, Proteins of Plant Origin ...

Proteins of Plant Origin Vegetable Proteins: Fresh vegetables are not considered to be a very good source of proteins. On fresh weight basis, the average protein content of s

Explain food effects on drug excretion, Explain Food Effects on Drug Excret...

Explain Food Effects on Drug Excretion? Food and nutrients can alter the re-absorption of drugs from the renal tubes. Urinary acidity affects drug re-absorption from the renal

Minerals and reproduction, Minerals and reproduction The mechanism of mine...

Minerals and reproduction The mechanism of mineral-reproduction interactions is not fully understood because  of the complexity of neuro-hormonal dialogue. Some minerals act direc

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd