Anticoagulants, Biology

Assignment Help:

ANTICOAGULANTS

(a) Heparin (hepar = liver) . It is synthesized by mast cells of connective tissue and liver cells. It is a heteropolysaccharide. It increases the effectivity of antithrombin III (a - globulin) which inactivates the thrombin so prevents conversion of fibrinogen into fibrin.

(b) Hirudin. It is an anticoagulant present in the saliva of salivary glands of leech and is mixed with blood of host during its storage in its crop.

(c) Warfarin. It is an anticoagulant of plant origin, which when given to a patient, lowers the formation of prothrombin and factors VII, IX and X from liver cells by lowering the activity of Vitamin K.

(d) Sodium oxalate, sodium citrate and EDT A (Ethylene diamine tetra acetic acid) are used as anticoagulants in blood banks as these bind Ca++, so these are called chelating agents. .

(e) Chilling of blood also delays blood clotting as it lowers the activity of enzymes involved in blood clotting.

 

ROLE OF VITAMIN-K IN BLOOD CLOTTING -

Vitamin K, also called anti-haemorrhagic factor, is a fat soluble vitamin and is essential for the formation of prothrombin from the liver. Deficiency of vitamin K causes hypoprothrombinemia which interferes with blood clotting. Vitamin K is also synthesized by intestinal bacteria.


Related Discussions:- Anticoagulants

Proestrus - estrous cycle, Proestrus - Estrous cycle This precedes the...

Proestrus - Estrous cycle This precedes the next heat and is characterised by functional involution of the corpora lutea and preovulatory swelling of the follicles. Fluid coll

Essential for photosynthesis, Aim : To prove that light is essential for ph...

Aim : To prove that light is essential for photosynthesis. Apparatus : A potted plant, a light screen, beaker, iodine solution. Procedure : Keep a potted plant in darkness for tw

Define about the paper electrophoresis, Define about the Paper electrophore...

Define about the Paper electrophoresis? In paper electrophoresis the sample is applied to a point on a strip of filter paper or cellulose acetate moistened with buffer solution

Hypothalamus and pituitary, Hypothalamus and Pituitary The most obviou...

Hypothalamus and Pituitary The most obvious neuroendocrine link is between the hypothalamus and pituitary. The hypothalamus is a part of the brain which is connected to the pi

Indications for surgery-tricuspid valve disease, Indications for Surgery : ...

Indications for Surgery : Echocardiography or right heart catheterization can quantify tricuspid stenosis. It is categorized as Tricuspid valve repair is advised when ther

Poultry and duck diseases-avian influenza, Avian influenza The etiologi...

Avian influenza The etiological a gentisa via ninfluenz a type A virus und e r the family Orthomyxoviridae. Avian influenza pandemics in Pakistan, Nepal and Myanamar (1995) and

How two organisms are interdependent, Give an example of how two organisms ...

Give an example of how two organisms are interdependent. Animals generate carbon dioxide and water, which is required by plants. Accept all reasonable answers.

Lower respiratory tract, Lower Respiratory Tract: Trachea:   ...

Lower Respiratory Tract: Trachea:   Trachea or windpipe  is 12 cm long, 2.5 cm in diameter lying in front of the esophagus and  ends opposite the fourth dorsal

Pathophysiology of constrictive pericarditis, Q. Pathophysiology of constri...

Q. Pathophysiology of constrictive pericarditis? Ans. The thickened and rigid pericardium causes constriction of the heart and restricts ventricular dialatation and diasto

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd