Anticoagulants, Biology

Assignment Help:

ANTICOAGULANTS

(a) Heparin (hepar = liver) . It is synthesized by mast cells of connective tissue and liver cells. It is a heteropolysaccharide. It increases the effectivity of antithrombin III (a - globulin) which inactivates the thrombin so prevents conversion of fibrinogen into fibrin.

(b) Hirudin. It is an anticoagulant present in the saliva of salivary glands of leech and is mixed with blood of host during its storage in its crop.

(c) Warfarin. It is an anticoagulant of plant origin, which when given to a patient, lowers the formation of prothrombin and factors VII, IX and X from liver cells by lowering the activity of Vitamin K.

(d) Sodium oxalate, sodium citrate and EDT A (Ethylene diamine tetra acetic acid) are used as anticoagulants in blood banks as these bind Ca++, so these are called chelating agents. .

(e) Chilling of blood also delays blood clotting as it lowers the activity of enzymes involved in blood clotting.

 

ROLE OF VITAMIN-K IN BLOOD CLOTTING -

Vitamin K, also called anti-haemorrhagic factor, is a fat soluble vitamin and is essential for the formation of prothrombin from the liver. Deficiency of vitamin K causes hypoprothrombinemia which interferes with blood clotting. Vitamin K is also synthesized by intestinal bacteria.


Related Discussions:- Anticoagulants

How many grams of sodium dodecyl sulfate need, How many grams of sodium dod...

How many grams of sodium dodecyl sulfate (mw = 288.37) would you dissolve in 80mLs of water to make a 20% solution of SDS?

Illustrate the advantages of ridgemapping, Advantages of Ridgemapping T...

Advantages of Ridgemapping This procedure is a good indicator of the available bone width and helps in understanding the angulation of the available bone to the eventual prosth

Typical conformation of the age pyramids, Q. What is the typical conformati...

Q. What is the typical conformation of the age pyramids of underdeveloped countries? The age pyramids of the peripheral countries or the underdeveloped countries have character

Headache associated with neurological diseases, Headache Associated with Ne...

Headache Associated with Neurological Diseases Headache is a symptom of many nervous system disorders, usually resulting from the distortion of pain sensitive structures. Commo

What is covalent bonds, What is covalent bonds? Covalent Bonds :  Cov...

What is covalent bonds? Covalent Bonds :  Covalent bonds form when atoms share electrons in order to become more stable. Instead of gaining electrons or losing electrons enti

Embryonic induction and cell determination, Embryonic Induction and Cell De...

Embryonic Induction and Cell Determination The cell determination or fate of embryonic cells is regulated through factors which may reside within the embryonic cells or by the

What is the difference between phenotype and genotype, What is genotype? Wh...

What is genotype? What is the difference between phenotype and genotype? The Genotype is the genes, DNA nucleotide sequences contained in the chromosomes of an individual, whic

Define nutritional management of celiac disease, Define Nutritional Managem...

Define Nutritional Management of Celiac Disease? A gluten-free diet is the major therapy for celiac disease patients, particularly children, and may be needed for lifelong adhe

Thermodynamics and cell shapes, Thermodynamics and Cell Shapes Why are...

Thermodynamics and Cell Shapes Why are protoplasts (cells devoid of cell wall) spherical? Why are most of the unicellular organisms (prokaryotes and eukaryotes) spherical? A s

Maintenance and regulation of peripheral circulation, Maintenance and Regul...

Maintenance and Regulation of Peripheral Circulation Pressure receptors (baroreceptors) located in the wall of the internal carotid arteries and in the arch of aorta, when

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd