Anticoagulants, Biology

Assignment Help:

ANTICOAGULANTS

(a) Heparin (hepar = liver) . It is synthesized by mast cells of connective tissue and liver cells. It is a heteropolysaccharide. It increases the effectivity of antithrombin III (a - globulin) which inactivates the thrombin so prevents conversion of fibrinogen into fibrin.

(b) Hirudin. It is an anticoagulant present in the saliva of salivary glands of leech and is mixed with blood of host during its storage in its crop.

(c) Warfarin. It is an anticoagulant of plant origin, which when given to a patient, lowers the formation of prothrombin and factors VII, IX and X from liver cells by lowering the activity of Vitamin K.

(d) Sodium oxalate, sodium citrate and EDT A (Ethylene diamine tetra acetic acid) are used as anticoagulants in blood banks as these bind Ca++, so these are called chelating agents. .

(e) Chilling of blood also delays blood clotting as it lowers the activity of enzymes involved in blood clotting.

 

ROLE OF VITAMIN-K IN BLOOD CLOTTING -

Vitamin K, also called anti-haemorrhagic factor, is a fat soluble vitamin and is essential for the formation of prothrombin from the liver. Deficiency of vitamin K causes hypoprothrombinemia which interferes with blood clotting. Vitamin K is also synthesized by intestinal bacteria.


Related Discussions:- Anticoagulants

Features of the gastrulation, Features of the Gastrulation The signifi...

Features of the Gastrulation The significant features of the gastrulation are: a) Proteins of many new types that were not present in the egg or blastula begin to be synthe

Name the group of fungi which belong to fermentation, Truffles, morels and ...

Truffles, morels and the many yeasts that are basic to fermentation processes belong to this group of fungi. These fung are termed as: a) Phycomycetes b) Ascomycetes c)

What are the main components of the cytoskeleton, The cytoskeleton is a net...

The cytoskeleton is a network of very little tubules and filaments spread throughout the cytoplasm of eukaryotic cells. It is made of microtubules, microfilaments and intermediate

Explain total anomalous pulmonary, Explain Total Anomalous pulmonary Venous...

Explain Total Anomalous pulmonary Venous Connection (TAPVC) ? In this congenital anomaly there is no direct communication between the pulmonary veins and the left atrium. All

What is self-jamming, What is Self-jamming Unless all of the mobile cli...

What is Self-jamming Unless all of the mobile client are perfectly synchronized, the arriving transmissions from multiple clients will not be perfectly aligned on chip boundari

Intermediate and the definitive hosts of the plasmodium, Q. What are the in...

Q. What are the intermediate and the definitive hosts of the plasmodium? In the life-cycle of the plasmodium humans are the intermediate hosts (where asexual reproduction takes

Can we prevent ketoacidosis, Q. Can we prevent ketoacidosis? Normally, ...

Q. Can we prevent ketoacidosis? Normally, while maintaining a good sugar control, there is a very little danger of ketoacidosis. One should test for ketones under the following

Define affluence availability of food as factor for obesity, Define Affluen...

Define Affluence and abundant availability of food as factor for obesity? With increasing affluence, increase in purchasing power and abundance of food, people tend to eat more

Determine the membrane voltage of neuron b, Consider Neuron B in the frog c...

Consider Neuron B in the frog central nervous system whose plasma membrane has a previously unknown channel that is selectively conductive to a newly discovered tetravalent anion n

Activitiesthat cause fish kills, Explain how human activities can cause an ...

Explain how human activities can cause an imbalance in biogeochemical cycling and lead to problems such as cultural eutrophication and fish kills

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd