Anticoagulants, Biology

Assignment Help:

ANTICOAGULANTS

(a) Heparin (hepar = liver) . It is synthesized by mast cells of connective tissue and liver cells. It is a heteropolysaccharide. It increases the effectivity of antithrombin III (a - globulin) which inactivates the thrombin so prevents conversion of fibrinogen into fibrin.

(b) Hirudin. It is an anticoagulant present in the saliva of salivary glands of leech and is mixed with blood of host during its storage in its crop.

(c) Warfarin. It is an anticoagulant of plant origin, which when given to a patient, lowers the formation of prothrombin and factors VII, IX and X from liver cells by lowering the activity of Vitamin K.

(d) Sodium oxalate, sodium citrate and EDT A (Ethylene diamine tetra acetic acid) are used as anticoagulants in blood banks as these bind Ca++, so these are called chelating agents. .

(e) Chilling of blood also delays blood clotting as it lowers the activity of enzymes involved in blood clotting.

 

ROLE OF VITAMIN-K IN BLOOD CLOTTING -

Vitamin K, also called anti-haemorrhagic factor, is a fat soluble vitamin and is essential for the formation of prothrombin from the liver. Deficiency of vitamin K causes hypoprothrombinemia which interferes with blood clotting. Vitamin K is also synthesized by intestinal bacteria.


Related Discussions:- Anticoagulants

Explain neurologic disease, Explain Neurologic disease For patients wit...

Explain Neurologic disease For patients with facial nerve palsy alone, oral doxycycline or amoxicillin may be effective. Patients with other neurologic involvement, such as men

Circulatory system, Circulatory system, closed is a system which uses a co...

Circulatory system, closed is a system which uses a continuous series of the vessels of different sizes to deliver blood to body cells and return it back to the heart; it is found

What is consciousness, The importance of the brain in our everyday lives ca...

The importance of the brain in our everyday lives can never be underestimated. The brain has physical properties that are in a constant state of flux. The brain never rests totally

Aortic valvotomy-surgical techniques, Aortic Valvotomy :  These days ...

Aortic Valvotomy :  These days aortic valvotomy even in neonates and critically ill infants is done under cardio pulmonary bypass. Through a median stemotomy, ascending aorta

When it is said that a bacteria is an obligate anaerobe, What is meant when...

What is meant when it is said that a bacteria is an obligate anaerobe? Obligate anaerobes are the living beings that do not survive in the presence of oxygen. For instance, the

Explain autoxidation, Autoxidation It is generally agreed that "autoxid...

Autoxidation It is generally agreed that "autoxidation", that is, the reaction with molecular oxygen via a self - catalytic mechanism, is the main reaction involved  in oxidati

Digestive system, Digestive system is one of eleven major body organ syste...

Digestive system is one of eleven major body organ systems in animals; it converts food from the external environment into the nutrient molecules which can be used and stored by t

Explain what is prosthetic valve endocarditis, Explain what is Prosthetic V...

Explain what is Prosthetic Valve Endocarditis (PVE) ? Prosthetic valve endocarditis (PVE) is called EARLY when symptoms begin within 60 days of surgery and LATE when the onset

How does one get infected by etec, Q. How does one get infected by Enteroto...

Q. How does one get infected by Enterotoxigenic escherichia coli gastroenteritis(ETEC)? Infection occurs when a person eats food or drinks water or ice contaminated with ETEC

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd