Anticoagulants, Biology

Assignment Help:

ANTICOAGULANTS

(a) Heparin (hepar = liver) . It is synthesized by mast cells of connective tissue and liver cells. It is a heteropolysaccharide. It increases the effectivity of antithrombin III (a - globulin) which inactivates the thrombin so prevents conversion of fibrinogen into fibrin.

(b) Hirudin. It is an anticoagulant present in the saliva of salivary glands of leech and is mixed with blood of host during its storage in its crop.

(c) Warfarin. It is an anticoagulant of plant origin, which when given to a patient, lowers the formation of prothrombin and factors VII, IX and X from liver cells by lowering the activity of Vitamin K.

(d) Sodium oxalate, sodium citrate and EDT A (Ethylene diamine tetra acetic acid) are used as anticoagulants in blood banks as these bind Ca++, so these are called chelating agents. .

(e) Chilling of blood also delays blood clotting as it lowers the activity of enzymes involved in blood clotting.

 

ROLE OF VITAMIN-K IN BLOOD CLOTTING -

Vitamin K, also called anti-haemorrhagic factor, is a fat soluble vitamin and is essential for the formation of prothrombin from the liver. Deficiency of vitamin K causes hypoprothrombinemia which interferes with blood clotting. Vitamin K is also synthesized by intestinal bacteria.


Related Discussions:- Anticoagulants

Enzyme specificity, Enzyme Specificity Enzymes play a critical role wit...

Enzyme Specificity Enzymes play a critical role within biological systems through helping reactions to occur beneath the commonly mild conditions in that organisms live. Enzyme

What is an example of an ion of biological importance, What is an example o...

What is an example of an ion of biological importance? Sodium in one, but so are potassium and calcium

Explain dicotyledons, Dicotyledons (2,00,000 species) The dicot's are o...

Dicotyledons (2,00,000 species) The dicot's are of diverse nature. The leaves are net veined, stem contains ring of vascular bundles, cambium tissue is present so secondary

Name the large intestine under which there is appendix, Name the sac-like, ...

Name the sac-like, blind pouch of large intestine, situated below the level of junction of the small intestine into the side of large intestine. At the lower portion of this pouch

What are secondary roots, What are secondary roots? In origin how secondary...

What are secondary roots? In origin how secondary roots differentiate from shoots? Secondary roots are ramifications of the primary (major) root. The secondary roots emerge fro

What is adp phosphorylation, What is ADP phosphorylation? What respectively...

What is ADP phosphorylation? What respectively are photophosphorylation and oxidative phosphorylation? ADP phosphorylation is the addition of one inorganic phosphate in the mol

Crustacea - feeding and digestion in arthropods, Crustacea - Feeding and Di...

Crustacea - Feeding and Digestion in Arthropods Branchiopods (Anacostraca) give a good instance for filter feeding mechanism. The appendages are of foliaceous type (leaf-like)

Define the term - functional magnetic resonance imaging, Define the term - ...

Define the term - Functional magnetic resonance imaging Functional magnetic resonance imaging (fMRI) is a recent development that permits simultaneous measurements of the brain

Explain glycophorin, Since erythrocytes  red blood cells do not hold any su...

Since erythrocytes  red blood cells do not hold any sub cellular  organelles they are essentially  a membranous  sac for carrying  haemoglobin their plasma membrane  is a convenien

Vein grafts-longevity of conduits long term conduits, Vein Grafts :  ...

Vein Grafts :  At the end of ten years only 50 per cent of saphenous vein grafts are paten1 and 50 per cent of the rest may have significant atherosclerotic changes. In a

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd