Anticoagulants, Biology

Assignment Help:

ANTICOAGULANTS

(a) Heparin (hepar = liver) . It is synthesized by mast cells of connective tissue and liver cells. It is a heteropolysaccharide. It increases the effectivity of antithrombin III (a - globulin) which inactivates the thrombin so prevents conversion of fibrinogen into fibrin.

(b) Hirudin. It is an anticoagulant present in the saliva of salivary glands of leech and is mixed with blood of host during its storage in its crop.

(c) Warfarin. It is an anticoagulant of plant origin, which when given to a patient, lowers the formation of prothrombin and factors VII, IX and X from liver cells by lowering the activity of Vitamin K.

(d) Sodium oxalate, sodium citrate and EDT A (Ethylene diamine tetra acetic acid) are used as anticoagulants in blood banks as these bind Ca++, so these are called chelating agents. .

(e) Chilling of blood also delays blood clotting as it lowers the activity of enzymes involved in blood clotting.

 

ROLE OF VITAMIN-K IN BLOOD CLOTTING -

Vitamin K, also called anti-haemorrhagic factor, is a fat soluble vitamin and is essential for the formation of prothrombin from the liver. Deficiency of vitamin K causes hypoprothrombinemia which interferes with blood clotting. Vitamin K is also synthesized by intestinal bacteria.


Related Discussions:- Anticoagulants

Explain the maintenance of weight loss, Explain the Maintenance of Weight L...

Explain the Maintenance of Weight Loss? Once an individual has managed to lose weight to a desirable level, it must not be assumed that the weight loss will be maintained autom

Gene expression is controlled by chromatin state, Gene expression is contro...

Gene expression is controlled by chromatin state, _______ and _________. a. transcription factors and epigenetic regulators b. polymerases and control proteins c. delta and tau pro

Explain about folic acid, Explain about Folic acid Folic acid occurs as...

Explain about Folic acid Folic acid occurs as a yellow or orange-yellow, microcrystalline powder, almost without odour and taste. Water content of folic acid is up to 8.5%. Fol

What percentage of the offspring purple flowers have, Purple (P) flowers ar...

Purple (P) flowers are dominant and white (p) flowers are recessive. A homozygous dominant purple flower is crossed with a homozygous recessive white flower. what percentage of the

Incompatibility - pollination and fertilization, Incompatibility - Pollinat...

Incompatibility - Pollination and Fertilization Plants growing under natural conditions have a preference for their mating partners. The stigma of the female parent receives a

What are the three categories of food protein, What are the three categorie...

What are the three categories in which food protein sources can be divided into Protein food sources can be separated into the following three categories: Proteins of pl

What are the preservation of insulin, What are the Preservation of Insulin ...

What are the Preservation of Insulin Regular insulin is stable for 18 months at 23.8 0 C and Lente insulin are stable for 24 months at this temperature. Although refrigeration

Obelia, what are the economic importance of obelia?

what are the economic importance of obelia?

What is biochemical characteristics, What is Biochemical Characteristics? ...

What is Biochemical Characteristics? In the last section we have learnt about the importance of biochemical tests. It must be clear now that biochemical tests are used to -

Endocrine glands that regulate sexual activity in males, Q. What are the en...

Q. What are the endocrine glands that regulate sexual activity in males? How does this regulation work and what are the involved hormones? In males the sexual activity is regul

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd