Anticoagulants, Biology

Assignment Help:

ANTICOAGULANTS

(a) Heparin (hepar = liver) . It is synthesized by mast cells of connective tissue and liver cells. It is a heteropolysaccharide. It increases the effectivity of antithrombin III (a - globulin) which inactivates the thrombin so prevents conversion of fibrinogen into fibrin.

(b) Hirudin. It is an anticoagulant present in the saliva of salivary glands of leech and is mixed with blood of host during its storage in its crop.

(c) Warfarin. It is an anticoagulant of plant origin, which when given to a patient, lowers the formation of prothrombin and factors VII, IX and X from liver cells by lowering the activity of Vitamin K.

(d) Sodium oxalate, sodium citrate and EDT A (Ethylene diamine tetra acetic acid) are used as anticoagulants in blood banks as these bind Ca++, so these are called chelating agents. .

(e) Chilling of blood also delays blood clotting as it lowers the activity of enzymes involved in blood clotting.

 

ROLE OF VITAMIN-K IN BLOOD CLOTTING -

Vitamin K, also called anti-haemorrhagic factor, is a fat soluble vitamin and is essential for the formation of prothrombin from the liver. Deficiency of vitamin K causes hypoprothrombinemia which interferes with blood clotting. Vitamin K is also synthesized by intestinal bacteria.


Related Discussions:- Anticoagulants

Explain guar gum, Guar Gum Guar Gum is derived from seed of legume Cyam...

Guar Gum Guar Gum is derived from seed of legume Cyamopsis tetragonalobus resembling soyabean plant. Guar gum is composed of Galactomannan Galactose: mannose in the ratio 1:2.

Density independent factors, Density Independent Factors Density inde...

Density Independent Factors Density independent factors are the extrinsic factors which tend to regulate the density of a population in ways that are not correlated with its

Developmental biology, pioneers of developmental biology and their contribu...

pioneers of developmental biology and their contribution

Why isnt gas exchange done through cutaneous diffusion, In arthropods why i...

In arthropods why isn't gas exchange done through cutaneous diffusion? In arthropods the impermeability of the exoskeleton makes the passage of gases complex. In addition the n

What do you determine by atriopore, What do you determine by Atriopore? ...

What do you determine by Atriopore? The external opening to atrium. In cephalochordates water passes across pharyngeal slits into atrium and from there leaves through atriopore

Explain about the pharmaceutical management, Explain about the Pharmaceutic...

Explain about the Pharmaceutical Management? A person with BMI 30 and above may require pharmaceutical management in addition to dietary and lifestyle modifications. It may als

Explain the term bleeding, Bleeding Bleeding from injury to small blood...

Bleeding Bleeding from injury to small blood vessels pushed along the lateral wall of expanding maxillary sinus should be contained by bone wax or electrocautery rather than cr

Excretion in cockroach, EXCRETIO N IN COCKROACH- Animal is uricotelic....

EXCRETIO N IN COCKROACH- Animal is uricotelic. Excretory organs are malphighian tubules. 60-150 in 6-8 groups. In each group 10-15. Yellow coloured, blind tube, open in gut

Kidneys participate in the acid-basic equilibrium, Q. How do kidneys partic...

Q. How do kidneys participate in the regulation of the acid-basic equilibrium of the body? How are alkalosis and acidosis respectively corrected by the kidneys? Kidneys can reg

Xerarch - ecology, Xerarch - Ecology Successions initiated on bare roc...

Xerarch - Ecology Successions initiated on bare rock, wind-blown sand, rocky talus slopes, or other situations where there is an extreme deficiency of water are termed xerarch

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd