Anticoagulants, Biology

Assignment Help:

ANTICOAGULANTS

(a) Heparin (hepar = liver) . It is synthesized by mast cells of connective tissue and liver cells. It is a heteropolysaccharide. It increases the effectivity of antithrombin III (a - globulin) which inactivates the thrombin so prevents conversion of fibrinogen into fibrin.

(b) Hirudin. It is an anticoagulant present in the saliva of salivary glands of leech and is mixed with blood of host during its storage in its crop.

(c) Warfarin. It is an anticoagulant of plant origin, which when given to a patient, lowers the formation of prothrombin and factors VII, IX and X from liver cells by lowering the activity of Vitamin K.

(d) Sodium oxalate, sodium citrate and EDT A (Ethylene diamine tetra acetic acid) are used as anticoagulants in blood banks as these bind Ca++, so these are called chelating agents. .

(e) Chilling of blood also delays blood clotting as it lowers the activity of enzymes involved in blood clotting.

 

ROLE OF VITAMIN-K IN BLOOD CLOTTING -

Vitamin K, also called anti-haemorrhagic factor, is a fat soluble vitamin and is essential for the formation of prothrombin from the liver. Deficiency of vitamin K causes hypoprothrombinemia which interferes with blood clotting. Vitamin K is also synthesized by intestinal bacteria.


Related Discussions:- Anticoagulants

Describe integrative systems of the body, Q. Why is the endocrine system co...

Q. Why is the endocrine system considered one of the integrative systems of the body? What is the other physiological system that also has this function? The endocrine system i

What are some common laboratory techniques, What are some common laboratory...

What are some common laboratory techniques? During the course of these laboratory sessions, you will be usual to become proficient in the performance of the following laborator

Classification scheme of protozoa, Classification Scheme of Protozoa ...

Classification Scheme of Protozoa Phylum Myxozoa Parasites of lower vertebrates especially fish and invertebrates. Phylum Microspora Parasites of inv

What is biogenetic law and define bilateral symmetry, What is Biogenetic La...

What is Biogenetic Law and define Bilateral symmetry? In brief, ontogeny recapitulates phylogeny. Or, developmental or embryological sequence of an animal repeats the evolution

Explain ketoconazole, Explain Ketoconazole It is now seldom used. The ...

Explain Ketoconazole It is now seldom used. The other azoles have fewer adverse effects and are usually preferred. Ketoconazole remains an option for treatment of infections w

Define needle selection for suturing, Define Needle selection for Suturing ...

Define Needle selection for Suturing 1. Needle with a reverse cutting edge "the cutting edge is outside the curve" is preferable, because it prevents tearing, 2. Conventiona

Explain the function of cell walls, What is plant cell walls made of? ...

What is plant cell walls made of? Explain the function of cell walls? Plant cell walls are made of cellulose embedded in carbohydrates and proteins. Cell walls help su

Polyarthritis, It is the most common (occurring in 75 per cent cases of ARF...

It is the most common (occurring in 75 per cent cases of ARF) manifestation of ARF. It involves large joints, it is typically fleeting in character shifting from one large joint t

Describe metabolic syndrome, Describe Metabolic Syndrome ? As discussed...

Describe Metabolic Syndrome ? As discussed, the risk factors like obesity, high blood pressure, high blood glucose or impaired glucose tolerance, and dyslipidaeinia are very im

What is the function of vitamin e, Q. What is the function of vitamin E? In...

Q. What is the function of vitamin E? In which foods can it be found? Vitamin E is also known as tocopherol is a fat-soluble vitamin that participates as coenzyme in the respir

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd