Anticoagulants, Biology

Assignment Help:

ANTICOAGULANTS

(a) Heparin (hepar = liver) . It is synthesized by mast cells of connective tissue and liver cells. It is a heteropolysaccharide. It increases the effectivity of antithrombin III (a - globulin) which inactivates the thrombin so prevents conversion of fibrinogen into fibrin.

(b) Hirudin. It is an anticoagulant present in the saliva of salivary glands of leech and is mixed with blood of host during its storage in its crop.

(c) Warfarin. It is an anticoagulant of plant origin, which when given to a patient, lowers the formation of prothrombin and factors VII, IX and X from liver cells by lowering the activity of Vitamin K.

(d) Sodium oxalate, sodium citrate and EDT A (Ethylene diamine tetra acetic acid) are used as anticoagulants in blood banks as these bind Ca++, so these are called chelating agents. .

(e) Chilling of blood also delays blood clotting as it lowers the activity of enzymes involved in blood clotting.

 

ROLE OF VITAMIN-K IN BLOOD CLOTTING -

Vitamin K, also called anti-haemorrhagic factor, is a fat soluble vitamin and is essential for the formation of prothrombin from the liver. Deficiency of vitamin K causes hypoprothrombinemia which interferes with blood clotting. Vitamin K is also synthesized by intestinal bacteria.


Related Discussions:- Anticoagulants

Define procedure for testing the presence of starch in milk, Define Procedu...

Define Procedure for Testing the Presence of Starch in Milk 1. Take 1 ml of milk sample in a test tube. 2. Add few drops of iodine solution. (2.5 gm of iodine is dissolved i

Write short note on cholesterol, Cholesterol, from stereos (solid) and the...

Cholesterol, from stereos (solid) and the Greek chole- (bile) followed by the chemical suffix -ol for an alcohol is an organic chemical substance classified as a waxy steroid of fa

Give some examples of cloning and molecular biology, Examples of cloning an...

Examples of cloning and molecular biology cloning may produce heterozygous individuals (as mother was heterozygous) and suggests a way to get pure breeding cats molecu

Explain seed gums, Seed gums Polysaccharides derived from plants and se...

Seed gums Polysaccharides derived from plants and seeds have been in use for thousand of years. Seed gums are a group of polysaccharides with the following properties: S

Give the introduction to evaluation of patient clinical, Give the introduct...

Give the introduction to evaluation of patient clinical examination ? A careful physical examinations is a very important for assessing the cardiovascular system and after prov

Salt glands in birds and reptiles, Salt Glands in Birds and Reptiles M...

Salt Glands in Birds and Reptiles Marine reptiles for example, iguanas, estuarine sea turtles, crocodiles, sea snakes and marine birds like the marine teleosts do not produce

Liquid manure handling, L iq uid manure handling This involves use of...

L iq uid manure handling This involves use of lot of water to flush the manure in to collection tank. Storage capacity depends on type of farm, irrigation facility, storage t

What is passive transport , The passive transport of molecules across a me...

The passive transport of molecules across a membrane does not require an input of metabolic energy. Rate of the diffusion or transport is proportional to the concentration gradient

Explain change in body composition of infants, Explain Change in body Compo...

Explain Change in body Composition of infants? The weight gain comprise of growth in the muscle, organ tissue, adipose and skeletal structure. One compartment of body which reg

Size of ecosystem, Size of Ecosystem As you know an ecosystem may be as...

Size of Ecosystem As you know an ecosystem may be as small and as simple as a cow dung pad or as complex and large as an ocean or the biosphere itself, comprising a wide variet

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd