Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
Antibody Structure:
An antibody molecule consist of two alike light chains (220 amino acids each) ad two similar heavy chains (about 440-450 amino acids each) held together by disulfide bridges; this create the monomeric form of antibody. Enzymes papain cleaves particular monomeric form into two fragments that bind to the antigen (designated as FAB; fragment with antigen binding) and one fragment which does bid to antigen but make crystals (so it's called Fc, crystal forming fragment). Approximate 100 amino acid long amino-terminal ends of both light and heavy chains add up to their variable region denoted VL and VH, correspondingly; the amino acid sequence of this regions of the heavy and light chains are known constant region (designated as CH and CL, correspondingly) as there is little variation in the amino acid sequence of this region between the antibodies belonging to the same class. Every antibody molecule has two antigen-binding domains or sites, particular domain being constituted by the variable regions of one light and one heavy chains of an antibody molecule form its effectors function domain that determines its interaction with the other components of the immune system. The light chains are of two types: and lambda (λ) and Kappa (K) ; the type of a light chain is find out by its constant region.
Different genes encode the Kappa (located in human chromosome 2) and lambda (chromosome 22) light chains, and the heavy chain (chromosome 14). The variable region of particular chain contains 3 highly variable regions known hyper variable regions and denoted as CDR1, CDR2and CDR3 (CDR = complementarily-determining region) divided by 4 constant regions known framework regions (this is designated as FR1, FR2, FR3, FR4). The constant region of particular heavy chain has 3 homologous regions (CH1, CH2 and CH3) which most likely originated from a common parental gene (3 tandem repeats of the parental gene, by following mutations).
Explain about the Soil morphology Soil morphology is the description of the soil body and its general characteristics. The morphology of the soil is expressed by number, kinds
Take the prepared slide of Euglena and focus it first under low power and next under the high power of tlie microscope. Observe tlie following characteristics: i) Euglena is an
Mechanics of Locomotion Among annelids, polychaetes, hence more primitive than the other two groups, show a more complex mode of locomotion. Necessarily, the locomotion in po
How is it structurally explained that the motor activity of the left side of the body is controlled by the right cerebral hemisphere and the motor activity of the right side of the
Q. Write the definition of communication? Communication is "a process of transmitting ideas, information, attitudes (images which we have formulated for ourselves) by the use o
what is the work of cerebellum
Before we proceed to discuss kin selection we should define the term altruism. It refers to the behaviour pattern of an individual in the population for the benefit of other member
Explain how salivary amylase works on foods like crackers
describe the factors which decide the broad area of scientific activity?
Q. Prevention of Coronary Heart Diseases? In view of the steep rise in the incidence of chronic degenerative coronary heart diseases, several programmes have been formulated to
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +91-977-207-8620
Phone: +91-977-207-8620
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd