Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
Antibody Structure:
An antibody molecule consist of two alike light chains (220 amino acids each) ad two similar heavy chains (about 440-450 amino acids each) held together by disulfide bridges; this create the monomeric form of antibody. Enzymes papain cleaves particular monomeric form into two fragments that bind to the antigen (designated as FAB; fragment with antigen binding) and one fragment which does bid to antigen but make crystals (so it's called Fc, crystal forming fragment). Approximate 100 amino acid long amino-terminal ends of both light and heavy chains add up to their variable region denoted VL and VH, correspondingly; the amino acid sequence of this regions of the heavy and light chains are known constant region (designated as CH and CL, correspondingly) as there is little variation in the amino acid sequence of this region between the antibodies belonging to the same class. Every antibody molecule has two antigen-binding domains or sites, particular domain being constituted by the variable regions of one light and one heavy chains of an antibody molecule form its effectors function domain that determines its interaction with the other components of the immune system. The light chains are of two types: and lambda (λ) and Kappa (K) ; the type of a light chain is find out by its constant region.
Different genes encode the Kappa (located in human chromosome 2) and lambda (chromosome 22) light chains, and the heavy chain (chromosome 14). The variable region of particular chain contains 3 highly variable regions known hyper variable regions and denoted as CDR1, CDR2and CDR3 (CDR = complementarily-determining region) divided by 4 constant regions known framework regions (this is designated as FR1, FR2, FR3, FR4). The constant region of particular heavy chain has 3 homologous regions (CH1, CH2 and CH3) which most likely originated from a common parental gene (3 tandem repeats of the parental gene, by following mutations).
Explain the Recommended Dietary Allowance for nicotinic acid? There are various factors and which niacin requirements depend. These are energy Utilization, body size and dietar
Porcine rotavirus Piglet diarrhoea and mortality are gaining importance and the viral agent which is highly incriminated in such episodes is porcine rotavirus. The clinical featur
Valves of the Heart There are four valves which are flap-like structures that function to maintain unidirectional (forward) blood flow through the heart chambers. These va
Basic Physical Concepts of Plant Water Relation The main idea of this section is to explain the concept of chemical potential of water or water potential and the effect of var
Multipotent SCs: are cells differentiated & form a number of other tissues, while their sources are not fetal tissue; umblical cord blood & postnatal stem cells including dental p
Define the term- Adaptation The terms scotopic and photopic vision are relative to the lighting conditions of an individual place. Light adaptation is a very quick process and
Isomer : Existence of different compounds having same molecular form but different structural forms.
Dietary counseling based on the food pyramid concept and the food to target concept will be quite useful in the management of the disease. The optimal age for discontinuing the
Hermaphroditism You would have completely appreciated now that sexual reproduction is definitely the more advanced type of reproduction. It gives for combination of genes from
GERENAL CHARACTERICS OF PHYLUM ANNELIDA
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +91-977-207-8620
Phone: +91-977-207-8620
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd