Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
Antibody Structure:
An antibody molecule consist of two alike light chains (220 amino acids each) ad two similar heavy chains (about 440-450 amino acids each) held together by disulfide bridges; this create the monomeric form of antibody. Enzymes papain cleaves particular monomeric form into two fragments that bind to the antigen (designated as FAB; fragment with antigen binding) and one fragment which does bid to antigen but make crystals (so it's called Fc, crystal forming fragment). Approximate 100 amino acid long amino-terminal ends of both light and heavy chains add up to their variable region denoted VL and VH, correspondingly; the amino acid sequence of this regions of the heavy and light chains are known constant region (designated as CH and CL, correspondingly) as there is little variation in the amino acid sequence of this region between the antibodies belonging to the same class. Every antibody molecule has two antigen-binding domains or sites, particular domain being constituted by the variable regions of one light and one heavy chains of an antibody molecule form its effectors function domain that determines its interaction with the other components of the immune system. The light chains are of two types: and lambda (λ) and Kappa (K) ; the type of a light chain is find out by its constant region.
Different genes encode the Kappa (located in human chromosome 2) and lambda (chromosome 22) light chains, and the heavy chain (chromosome 14). The variable region of particular chain contains 3 highly variable regions known hyper variable regions and denoted as CDR1, CDR2and CDR3 (CDR = complementarily-determining region) divided by 4 constant regions known framework regions (this is designated as FR1, FR2, FR3, FR4). The constant region of particular heavy chain has 3 homologous regions (CH1, CH2 and CH3) which most likely originated from a common parental gene (3 tandem repeats of the parental gene, by following mutations).
Q. What is Sulphonylureas? Sulphonylureas: Tolbutarnide is the mildest and its effect remains for 8 hours hence 2-3 doses need to be taken. Another drug chlorpropamide needs on
What are the uses of construction of a retaining wall? The retaining wall is constructed whenever space requirement do not allow the natural slope to be formed for an excavatio
Q. Which are the subproducts of the photochemical phase that are essential for the chemical stage of photosynthesis? The chemical stage of photosynthesis depends on ATP and NAD
Q. Inhibition of microorganisms in food? Microorganisms use our food supply as a source of nutrients and energy. They increase their numbers by utilizing nutrients. This can re
discribe tha bantham and hookers systeam of classification
S w i n e fever It is also known as hog cholera and results in high fever and prostration. E t iology : Pestivirus belonging to family Togaviridae is responsi
Q. Explain the communication process? Communication is a process by which information is exchanged between individuals through a common system of symbols, signs, or behavior. C
The °C and °F scales are equivalent at only one temperature. That is, x °C = x °F. Use the relationships for temperature conversions to DERIVE (FIND) that temperature. This problem
What is Active site Active site : The site on the surface of an enzyme to which substrate or substrates bind.
Question 1: Define Survey. List out advantages of surveys. Brief up different survey methods Definition of survey. Advantages of surveys Different survey methods
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +91-977-207-8620
Phone: +91-977-207-8620
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd