Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
Antibody Structure:
An antibody molecule consist of two alike light chains (220 amino acids each) ad two similar heavy chains (about 440-450 amino acids each) held together by disulfide bridges; this create the monomeric form of antibody. Enzymes papain cleaves particular monomeric form into two fragments that bind to the antigen (designated as FAB; fragment with antigen binding) and one fragment which does bid to antigen but make crystals (so it's called Fc, crystal forming fragment). Approximate 100 amino acid long amino-terminal ends of both light and heavy chains add up to their variable region denoted VL and VH, correspondingly; the amino acid sequence of this regions of the heavy and light chains are known constant region (designated as CH and CL, correspondingly) as there is little variation in the amino acid sequence of this region between the antibodies belonging to the same class. Every antibody molecule has two antigen-binding domains or sites, particular domain being constituted by the variable regions of one light and one heavy chains of an antibody molecule form its effectors function domain that determines its interaction with the other components of the immune system. The light chains are of two types: and lambda (λ) and Kappa (K) ; the type of a light chain is find out by its constant region.
Different genes encode the Kappa (located in human chromosome 2) and lambda (chromosome 22) light chains, and the heavy chain (chromosome 14). The variable region of particular chain contains 3 highly variable regions known hyper variable regions and denoted as CDR1, CDR2and CDR3 (CDR = complementarily-determining region) divided by 4 constant regions known framework regions (this is designated as FR1, FR2, FR3, FR4). The constant region of particular heavy chain has 3 homologous regions (CH1, CH2 and CH3) which most likely originated from a common parental gene (3 tandem repeats of the parental gene, by following mutations).
DIVERGENC E - In it blastomeres move in different directions i.e. inside the blastocoel the blastomeres move in different directions. The blastomeres which move inside i
I nfectious bronchitis (IB) Infectious bronchitis is a highly contagious respiratory disease of poultry, caused by a virus belonging to the family Coronaviridae. Its existence
What are some examples of the energetic function of organic molecules? As they are complex molecules, presenting lots of chemical bonds, organic molecules keeps large amount of
AMOEBA Systematic Position Amoeba was discovered by Russel von Rosenhoff in 1755. He called it the little proteus after the mythical sea god who is believed to be c
Hydrophily - Cross-pollination All hydrophytes are not necessarily pollinated by water. In fact most of the aquatic plant are anemophilous, e.g. Alisma, Nymphaea. Like anemoph
Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4
Coxal Glands There is a pair of coxal glands, in almost all the segments in Onychophora (Peripatus). Developmentally; in every segment a hollow follicle or somite arises and i
GAS T RUL A TIO N - Morphogenic movements are occured. 3 germinal layers are formed. Ectoderm, endoderm & mesoderm. Endoderm is formed first. Mesoderm is formed in the
A decrease in parasympathetic discharge to the heart leads to A. a decrease in the conductance of F-channels in SA node cells. B. an increase in the conductance of potassium
Two gene loci, A and B, assort independently, and alleles A and B are dominant over alleles a and b. Indicate the probablilities of producing .... an AB phenotype from a cross AaBb
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +91-977-207-8620
Phone: +91-977-207-8620
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd