Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
Antibody Structure:
An antibody molecule consist of two alike light chains (220 amino acids each) ad two similar heavy chains (about 440-450 amino acids each) held together by disulfide bridges; this create the monomeric form of antibody. Enzymes papain cleaves particular monomeric form into two fragments that bind to the antigen (designated as FAB; fragment with antigen binding) and one fragment which does bid to antigen but make crystals (so it's called Fc, crystal forming fragment). Approximate 100 amino acid long amino-terminal ends of both light and heavy chains add up to their variable region denoted VL and VH, correspondingly; the amino acid sequence of this regions of the heavy and light chains are known constant region (designated as CH and CL, correspondingly) as there is little variation in the amino acid sequence of this region between the antibodies belonging to the same class. Every antibody molecule has two antigen-binding domains or sites, particular domain being constituted by the variable regions of one light and one heavy chains of an antibody molecule form its effectors function domain that determines its interaction with the other components of the immune system. The light chains are of two types: and lambda (λ) and Kappa (K) ; the type of a light chain is find out by its constant region.
Different genes encode the Kappa (located in human chromosome 2) and lambda (chromosome 22) light chains, and the heavy chain (chromosome 14). The variable region of particular chain contains 3 highly variable regions known hyper variable regions and denoted as CDR1, CDR2and CDR3 (CDR = complementarily-determining region) divided by 4 constant regions known framework regions (this is designated as FR1, FR2, FR3, FR4). The constant region of particular heavy chain has 3 homologous regions (CH1, CH2 and CH3) which most likely originated from a common parental gene (3 tandem repeats of the parental gene, by following mutations).
what so special for phylum annelida
Q. What are branchiae? What are examples of animals that "breath" through branchiae? Branchiae also known as gills are small portions of richly vascularized tissues external or
How dissimilar are intracellular and extracellular digestion? What is the evolutionary benefit of extracellular digestion? Intracellular digestion is that in which the breaking
classification schemes and characterisitics used for this.
Pulmonary Stenosis : The obstruction may be valvar, infundibular or supra valvar.
A plant grown from one of Mendel's yellow peas is selfed. Five progeny peas are obtained from this self and they are all yellow. If the original selfed plant had been homozygous, w
Measures to control malaria infection: Malaria is a communicable disease caused by the female anopheles mosquito. a) Controlling mosquito population : Mosquito population can b
Q. What do you mean by Overgloves? The purpose of these gloves is to use time more efficiently and to protect the skin on the hands through minimizing the number of times that
Traumatology : This is the study of wounds. In other words we can say that traumatology is the study of wounds or injuries which can be caused by accidents or violence to a person
Future - Development Biology Fertilization in flowering plants is essential for sustaining life on earth. Production of most crops depends on the effectivity of the fertilisat
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +91-977-207-8620
Phone: +91-977-207-8620
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd