Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
Antibody Structure:
An antibody molecule consist of two alike light chains (220 amino acids each) ad two similar heavy chains (about 440-450 amino acids each) held together by disulfide bridges; this create the monomeric form of antibody. Enzymes papain cleaves particular monomeric form into two fragments that bind to the antigen (designated as FAB; fragment with antigen binding) and one fragment which does bid to antigen but make crystals (so it's called Fc, crystal forming fragment). Approximate 100 amino acid long amino-terminal ends of both light and heavy chains add up to their variable region denoted VL and VH, correspondingly; the amino acid sequence of this regions of the heavy and light chains are known constant region (designated as CH and CL, correspondingly) as there is little variation in the amino acid sequence of this region between the antibodies belonging to the same class. Every antibody molecule has two antigen-binding domains or sites, particular domain being constituted by the variable regions of one light and one heavy chains of an antibody molecule form its effectors function domain that determines its interaction with the other components of the immune system. The light chains are of two types: and lambda (λ) and Kappa (K) ; the type of a light chain is find out by its constant region.
Different genes encode the Kappa (located in human chromosome 2) and lambda (chromosome 22) light chains, and the heavy chain (chromosome 14). The variable region of particular chain contains 3 highly variable regions known hyper variable regions and denoted as CDR1, CDR2and CDR3 (CDR = complementarily-determining region) divided by 4 constant regions known framework regions (this is designated as FR1, FR2, FR3, FR4). The constant region of particular heavy chain has 3 homologous regions (CH1, CH2 and CH3) which most likely originated from a common parental gene (3 tandem repeats of the parental gene, by following mutations).
TYPES OF BLASTULA - Blastulas are of following type - 1 . STEREOBLASTULA - The blastocoel is very small. It's blastomere are less in num
Tropical seasonal forests - Ecosystem Tropical seasonal forests occur in regions where total annual rainfall is very high but segregated into pronounced wet and dry periods. T
Adverse Effects of Valacyclovir Valacyclovir is generally well tolerated; adverse effects are similar to those with acyclovir. GI disturbance, headache, rash, CNS effects such
(a) What are the immediate effects of exercise on the functions of (i) the heart, (ii) the lungs, (iii) the liver? (b) How do these changes help to meet the needs of exercise
Explain the Burden of Hypertension in heart diseases ? Since 1942, there have been several small and large population-based studies on Hypertension. A ineta-analysis showed an
Ask quesIn Cross 1, pure-breeding colored, starchy kernel plants (C1Wx/C1Wx) were crossed to plants pure-breeding for colorless, waxy kernels (c1 wx/c1 wx). The F1 of this cross we
Helobial Type - Endosperm This type of endosperm is intermediate between the nuclear and the cellular types. The division of the primary endosperm nucleus is followed by the f
Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4
A virus capsid containing vimentin, your protein of interest, gets into the cell nucleus and is broken down with the DNA being released. It is unknown whether the capsids themselve
what are the types of pseudopodia
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +91-977-207-8620
Phone: +91-977-207-8620
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd