Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
Antibody Structure:
An antibody molecule consist of two alike light chains (220 amino acids each) ad two similar heavy chains (about 440-450 amino acids each) held together by disulfide bridges; this create the monomeric form of antibody. Enzymes papain cleaves particular monomeric form into two fragments that bind to the antigen (designated as FAB; fragment with antigen binding) and one fragment which does bid to antigen but make crystals (so it's called Fc, crystal forming fragment). Approximate 100 amino acid long amino-terminal ends of both light and heavy chains add up to their variable region denoted VL and VH, correspondingly; the amino acid sequence of this regions of the heavy and light chains are known constant region (designated as CH and CL, correspondingly) as there is little variation in the amino acid sequence of this region between the antibodies belonging to the same class. Every antibody molecule has two antigen-binding domains or sites, particular domain being constituted by the variable regions of one light and one heavy chains of an antibody molecule form its effectors function domain that determines its interaction with the other components of the immune system. The light chains are of two types: and lambda (λ) and Kappa (K) ; the type of a light chain is find out by its constant region.
Different genes encode the Kappa (located in human chromosome 2) and lambda (chromosome 22) light chains, and the heavy chain (chromosome 14). The variable region of particular chain contains 3 highly variable regions known hyper variable regions and denoted as CDR1, CDR2and CDR3 (CDR = complementarily-determining region) divided by 4 constant regions known framework regions (this is designated as FR1, FR2, FR3, FR4). The constant region of particular heavy chain has 3 homologous regions (CH1, CH2 and CH3) which most likely originated from a common parental gene (3 tandem repeats of the parental gene, by following mutations).
A cell with a euploid number of chromosomes contains: A.one half of a complete set of chromosomes B.several complete sets of chromosomes C.the correct number of chromosomes D.two c
Planning the Nursing Care The goals of nursing care are: Identify the causative factor of megaloblastic anaemia. Administer appropriate vitamins depending on
Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4
Chemical disasters arise from harmful and potentially hazardous chemicals, which if released of misused can pose a threat to the environmental. Its range depends upon military and
What is the morphological characteristic that evolutionarily approximates the beings of the phylum Annelida to arthropods? The metameric feature, i.e., the body segmentation in
Enrichment of soil Indirect provision of minerals to grazing livestock includes mineral fertilization of pasture and altering soil pH, however this may not be always feasible
Gregor mendel was an austrain augustianian monk; his work most notably showed that. a. Alleles segregate during meosis b. Capital alleles are dominant c. The genetic material is pa
Q. Show the Use of Incineration for sterilization? This is an excellent method for rapidly destroying materials such as soiled dressings, animal carcasses, bedding and patholog
Isomer : Existence of different compounds having same molecular form but different structural forms.
Kinds of Ovules Ovules undergo varied degrees of curvature during development. The position of micropyle with respect to the funiculus becomes different and constitutes the b
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +91-977-207-8620
Phone: +91-977-207-8620
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd