Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
Animal disease model
The second area of transgenic application in agriculture is to develop lines of animals resistant to some specific damaging diseases. While the genes of interest may be expressed in the transgenic animals, so far there have been no projects that have progressed to the development of disease resistant animal lines. Prion diseases have had a major economic impact arid are a concern in the use of animal products for human use. This is particularly the case for BSE in cattle, and it is now almost certain that this has caused a new and terrible form of Creuzfeldt Jacob disease (CJD) in humans termed vCJD. Scrapie has been described in sheep for many years and, from the evidence of PrP knockouts in the mouse, removal of the PrP gene itself by gene knockout would be expected to produce animals resistant to prion diseases, without detrimental side effects.
Knockout of the Cftr gene in the sheep would be expected to produce a more accurate model of cystic fibrosis in humans due to similarities in lung physiology between sheep and humans. Furthermore sheep lungs are similar in size to those of humans thus enabling medical interventions delivering new drugs or therapy with the Cftr gene to be evaluated more realistically. There are of course major ethical issues which would have to be considered in generating potentially sick animals and these would have to be balanced alongside the practical benefits such a model could bring.
What is Multiple Alleles ? Obviously, diploid organisms, such as humans can have only two different alleles for a certain gene locus. However, new alleles are continuously bein
A large number of important drugs are derived from plants. For example Tubocuranin, derived from plant-based curare, is used as a muscle relaxant during surgery. Curianol, a Guy
What is Obesity in biochemical or physiological risk ? Obesity results from a complex interaction of genetic predisposition and environmental factors operating throughout an in
Explain Irradiation The physical process of exposing an object, system, or a material to a high radiant energy for the sterilization or preservation.
Q. Risk Factors for GDM? If any of the following risk factors are present in a woman, she may develop GDM: 1) Presence of obesity. 2) If any family members (parents, brot
Despite its importance, determining the value or worth of biodiversity is complex and often a cause for debate. This is largely due to the fact that the worth placed on biodiversit
Q. Described Microbiology of Air? Ans. You would realize that air, by nature, does not contain a natural flora of microorganisms. All that comes into air is by accident and i
Illustrate about the Chemical disinfection Sharp waste may cause injury and person may have diseases like Hepatitis B, Cand HIV/AIDS. Therefore it is important for to understa
Q. Filming Projection and Technique? Biplane ventriculography is preferred over single plane ventriculography because it gives more information without additional risk to the p
Which of the following is not true regarding the immune response? Answer The immune response uses chemical and phagocytic cells to destroy foreign cells. Once initiated, the immune
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +91-977-207-8620
Phone: +91-977-207-8620
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd