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Animal disease model
The second area of transgenic application in agriculture is to develop lines of animals resistant to some specific damaging diseases. While the genes of interest may be expressed in the transgenic animals, so far there have been no projects that have progressed to the development of disease resistant animal lines. Prion diseases have had a major economic impact arid are a concern in the use of animal products for human use. This is particularly the case for BSE in cattle, and it is now almost certain that this has caused a new and terrible form of Creuzfeldt Jacob disease (CJD) in humans termed vCJD. Scrapie has been described in sheep for many years and, from the evidence of PrP knockouts in the mouse, removal of the PrP gene itself by gene knockout would be expected to produce animals resistant to prion diseases, without detrimental side effects.
Knockout of the Cftr gene in the sheep would be expected to produce a more accurate model of cystic fibrosis in humans due to similarities in lung physiology between sheep and humans. Furthermore sheep lungs are similar in size to those of humans thus enabling medical interventions delivering new drugs or therapy with the Cftr gene to be evaluated more realistically. There are of course major ethical issues which would have to be considered in generating potentially sick animals and these would have to be balanced alongside the practical benefits such a model could bring.
Induction of Defensive Barriers in Plants Several polymers deposited near surface of plants form an effective barrier against invasion or stress. Cuticle (which consists of a
Differences between cells of Prokaryotes and Eukaryotes The prokaryotes also differ from the eukaryotes in many other ways, as you can see from Table. Table: Differences
Rainfall is high, sometimes higher than tropical rain forests but seasonal. There are pronounced wet and dry periods, and so are winter and summer seasons. The soils are brown in c
reproduction
Pantothenic acid (Calcium pantothenate) Calcium pantothenate is a white, loose, faintly hygroscopic powder without odour and of bitter taste. It is easily soluble in water, gly
harmful and benificial microbes
Molecular Biology - transgenesis Difficult to successfully insert the gene then successfully re-implant embryo possible pleiotropic effects low success rate / tak
Q. Explain the types of basic forces? Compression: This refers to the squeezing of the test material so that it still remains as a single undivided unit but may occupy less v
Explain why it is essential that muscle cells, during anaerobic respiration, convert pyruvic acid (pyruvate) into lactic acid, even though the conversion results in an accumulation
Parasitic Protozoan Out of the thousands of species of Protozoa, the majority are free living. However, many species from within the phyla Sarcomastigophora and Ciliophora are
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