Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
Animal disease model
The second area of transgenic application in agriculture is to develop lines of animals resistant to some specific damaging diseases. While the genes of interest may be expressed in the transgenic animals, so far there have been no projects that have progressed to the development of disease resistant animal lines. Prion diseases have had a major economic impact arid are a concern in the use of animal products for human use. This is particularly the case for BSE in cattle, and it is now almost certain that this has caused a new and terrible form of Creuzfeldt Jacob disease (CJD) in humans termed vCJD. Scrapie has been described in sheep for many years and, from the evidence of PrP knockouts in the mouse, removal of the PrP gene itself by gene knockout would be expected to produce animals resistant to prion diseases, without detrimental side effects.
Knockout of the Cftr gene in the sheep would be expected to produce a more accurate model of cystic fibrosis in humans due to similarities in lung physiology between sheep and humans. Furthermore sheep lungs are similar in size to those of humans thus enabling medical interventions delivering new drugs or therapy with the Cftr gene to be evaluated more realistically. There are of course major ethical issues which would have to be considered in generating potentially sick animals and these would have to be balanced alongside the practical benefits such a model could bring.
Patent Ductus Arteriosus (PDA) PDA is one of the most common cardiac anomalies. It occurs twice as frequently in girls as in boys. In patent ductus Arteriosus there is
Explain diet from Lifestyle Risk Factors ? The lifestyle factors are the way of living of an individual and comprise of the diet, smoking, alcohol, physical activity and stress
Define Steps To determine thermal resistance of a microorganism? Most food components and microorganisms obey first order reaction kinetics, which means that the destruction ra
Define the neurological disorders of dysphagia? In neurological disorders, damage to cranial nerves can lead to weak and poorly co- ordinated tongue movements, which results in
Explain the characterstics of Acute AR Murmur ? Characteristic: Relatively low pitched, decrescendo diastolic murmur, which may end part way through diastole. These murmurs ar
Soil Temperature Soil temperature is known to influence water absorption and ultimately transpiration to a considerable extent. In many plants water absorption is reduced shar
Explain the Flavour Binding? Some protein preparations, although acceptable from a functional and nutritional stand point, necessitate a deodorizing step to remove the bound of
What are the grasslands of North America and of South America respectively called? The steppe grasslands of North America are known as prairies. The grasslands of South America
Stored Metabolites - Seed and Fruit In a large majority of seeds food is stored in the cells of the endosperm. In coconut, wheat and castor bean for example, it is the endospe
What is Physiology: Root Pressure explain briiefly? Transport of water, minerals and nutrients within vascular plants is dramatically different from animals such as humans. Whe
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +91-977-207-8620
Phone: +91-977-207-8620
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd