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Animal disease model
The second area of transgenic application in agriculture is to develop lines of animals resistant to some specific damaging diseases. While the genes of interest may be expressed in the transgenic animals, so far there have been no projects that have progressed to the development of disease resistant animal lines. Prion diseases have had a major economic impact arid are a concern in the use of animal products for human use. This is particularly the case for BSE in cattle, and it is now almost certain that this has caused a new and terrible form of Creuzfeldt Jacob disease (CJD) in humans termed vCJD. Scrapie has been described in sheep for many years and, from the evidence of PrP knockouts in the mouse, removal of the PrP gene itself by gene knockout would be expected to produce animals resistant to prion diseases, without detrimental side effects.
Knockout of the Cftr gene in the sheep would be expected to produce a more accurate model of cystic fibrosis in humans due to similarities in lung physiology between sheep and humans. Furthermore sheep lungs are similar in size to those of humans thus enabling medical interventions delivering new drugs or therapy with the Cftr gene to be evaluated more realistically. There are of course major ethical issues which would have to be considered in generating potentially sick animals and these would have to be balanced alongside the practical benefits such a model could bring.
Determine about benefits of Jogging Jogging gives a sense of wellness to a diabetic patient. The frequency of jogging should be at least 3 days in week with a distance of 2 km
Aortic Valve Replacement : Technique: Surgical technique is not much different from what has already been described for aortic stenosis. Care must be taken to avoid VF
Plants are supplied with adequate amount of phosphorus Phosphorus has also been associated with early maturity of crops particularly the cereals. Its shortage is accompanied by
1) The presence of epicardial coronary artery stenosis caused by artherosclerotic plaques is by far the most frequent angiographic finding in any cardiac ischaemic syndrome. 2)
Q. What are the major divisions and representing species of the gymnosperms? This group of plants can be separated into conifers (pine, sequoia, cypress), that have flowers cal
Oncogene is the gene in a tumor virus or in the cancerous cells which, when transferred into the other cells, can cause the transformation (note which only certain cells are susce
Septa prevent oxygenated and deoxygenated blood. Give reason
What is the importance of the glucose blood level for human health? The glucose blood level (glycemia) must be kept normal. If it is abnormally low there is not enough glucose
Air pollution is complex in origin and varied in effect. It is very crucial from the point of human health. Every human being inhales about 15-22 kg of air daily and air is pollute
1. Hazard Is An Extreme Event Whereas Disaster Is Its Consequence. 2. A hazard can occur without human interference but it may become a disaster on account of careless
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