Angiotensin receptor blockers, Biology

Assignment Help:

Angiotensin receptor blockers block the final common pathway and provide a means of complete blockade of the system.

One of two subtypes of AII receptors, the AT1 receptor produces vasoconstriction and induces muscle cell proliferation when activated; the AT2 receptor produces antiproliferative effects upon activation. Currently available ARBs selectively block the AT1 receptor, producing vasodilatation and inhibiting muscle cell proliferation.

However, these agents do not produce increases in bradykinin, prostaglandins, and nitric oxide in the heart, blood vessels, and other tissues. They   should be considered as alternatives to ACE inhibitors in ACE-intolerant patients especially patients with chronic dry irritating cough and angiedema. Another potential use is to counteract ACE escape, the attenuation of the benefits of ACE inhibition that may occur with time.

Various agents available are losartan, valsartan, irbesartan, candesartan, telmisartan and eprosartan.


Related Discussions:- Angiotensin receptor blockers

What is cloning, What is cloning? The Cloning is the making of an organ...

What is cloning? The Cloning is the making of an organism genetically identical to another by means of genetic engineering. The foundation of cloning is the nucleus transpla

Human physiology, which bones forms lhe non moving muscle attachment in

which bones forms lhe non moving muscle attachment in

How much physical activity is enough, How much physical activity is enough?...

How much physical activity is enough? Although it is difficult to prescribe the optimum amount of physical activity, it is important to note that any exercise programme has to

Production of industrial compounds, Production of Industrial Compounds ...

Production of Industrial Compounds Cultured plant cells retain their metabolic potential and synthesise secondary products of commerce. Cell cultures can also be used as facto

Understanding behaviour of diabetic patients, Q. Understanding Behaviour of...

Q. Understanding Behaviour of diabetic patients? Beliefs  Each of us has a set of beliefs that were learned by us when we were young. These include religious beliefs and

Uptake of iron by enterocytes - non-haem iron absorption, Define Uptake of ...

Define Uptake of iron by enterocytes - Non Haem Iron Absorption? Ferrous iron traverses the brush border of the intestine better than the ferric iron. The mechanism of absorpti

Theory of embryology -recapitulation theory / biogenetic law, RECAPITUL A ...

RECAPITUL A TIO N THEORY / BIOGENETIC LAW It was proposed by Muller & Haeckel on the basis of Baer's law. According to it, in the development of animal phylum characters

What is crossing over?how meiosis related to this phenomenon, What is cross...

What is crossing over? How is meiosis related to this phenomenon? The Linked alleles for instance, A-b and a- B form the gametes A-b and a-B that maintain the linkage of the al

Medtronic-hall valve-types of valves, Medtronic-Hall Valve :  This is...

Medtronic-Hall Valve :  This is a low profile central tilting disc valve. The disc is made of pyrolitic carbon and housing is single piece of machined titanium. Introduced in

Synthesis of soluble proteins on the surface of lens, How is synthesis of s...

How is synthesis of soluble proteins taking equatorial part on the surface of lens? Synthesis of soluble proteins taking equatorial part on the surface of lens as follows: 1

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd