Agonists or antagonists, Other Subject

Assignment Help:

Somewhere between 30% and 50% of all drugs on the market target a G protein-coupled receptor. For each agent,

-          Write an in-depth description of the agent and its mechanism of action.

-          Are they agonists or antagonists?

-          What GPCR or GPCRs do they bind?

-          What is the endogenous ligand? Include in your descriptions the sources of the agents.

-          Were they isolated from nature, stumbled upon randomly, or intentionally synthesized?

-          When and by whom? If one of the agents is a "dirty drug," be sure to mention other sites of action besides the GPCRs.

-          If you can find the information, what signal transduction pathway is activated or inhibited by each drug?

-          What are the applications of your agents? Are they only used in research or does either have a clinical use?

Pharmacological agent and target

staurosporine and protein kinases

Signal transduction pathways represent a wealth of potential targets for pharmacological intervention.

-          Write an in-depth description of agent (staurosporine and protein kinases) and its mechanism of action. Include in your description the source of the agent.

-          Was it isolated from nature, stumbled upon randomly, or intentionally synthesized?

-          When and by whom?

-          If the agent is a "dirty drug," be sure to mention other sites of action.

-          What are the applications of the agent?

-          Is it only used in research or does it have a clinical use?

Be sure to cite all of your references.

NO DIRECT QUOTES! Write a single, cohesive response.


Related Discussions:- Agonists or antagonists

Process and community corrections models, Compare and contrast the justice/...

Compare and contrast the justice/due process and community corrections models for dealing with offenders in terms of each model's history, philosophy, and goals. Compare and contra

Write a note about building the magazine article, Question 1 Write a long ...

Question 1 Write a long note on feature writing and summarise techniques for writing a good feature Question 2 Write a note about building the magazine article Question 3 Writ

Propertiness of properly, Propertiness of Properly: Perhaps the lastin...

Propertiness of Properly: Perhaps the lasting significance of Victoria Park Racing lies in the fact that the conflict between the majority and minority views in this case thro

Aerodynamics, Are you able to do Aerodynamic assignments, Midterms?

Are you able to do Aerodynamic assignments, Midterms?

Explain the biological and physical aspects of ageing, Question: (a) Ex...

Question: (a) Explain carefully the biological and physical aspects of ageing and explain the impact of these factors on the ageing individual. (b) Show the age-specific pro

Explain Conditional selection, Explain Conditional selection. Conditio...

Explain Conditional selection. Conditional selection: While a marker is instructed to establish a connection from a specified incoming trunk to a specified outgoing trunk, it

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd