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Ablation experiment is an experiment designed to produce an animal deficient in one or the few cell types, in order to study cell lineage or the cell function. The logic is to make a transgenic mouse with a toxin gene (often known as diphtheria toxin) under control of a specialized promoter which activates only in the target cell type. When the embryo development progresses to the point where it starts to form the target tissue, the toxin gene is activated, and that particular tissue dies. Other tissues are not affected.
Cystic fibrosis (CF) is caused by a variety of mutations in the CFTR gene. Imagine you have identified a new single-base pair mutation (A→T) in an exon of the CFTR gene. You wish t
REPRODUCTIO N - It is not only production of new ones to increases its number but a means for the survival of a population on earth. Main aim is "survival and continuati
The dangers of working in labs with animals will be minimised if the following precautions are taken: 1. Wash all dissection instruments in disinfectant after use. 2. Never
Describe about the extra-ocular muscles The extra-ocular muscles are mainly involved in the maintenance of postural tonicity and performance of quick contractions. The prima
what is the difference between nitrogen fixation, nitrification ,assimilation and denitrification processes
List host factor which play important role in implant survival. Host factors: a) Medical status of the patient b) Habits - Smoking - Parafunctional habits c) O
Expression clone is a clone (plasmid in the bacteria, or might be a lambda phage in bacteria) which is designed to produce the protein from the DNA insert. Mammalian genes do not
Precautions to prevent from HIV To avoid HIV infection one should practice safe sex (use of condoms). Besides a few simple precautions are given for protection against HIV inf
Preparation on the Previous Day of Operation Remove all the jewellery, nail polish, cut nails. The patient's body is cleaned - shaving from chin to toe, inclu
General characteristics of phylum
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