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Ablation experiment is an experiment designed to produce an animal deficient in one or the few cell types, in order to study cell lineage or the cell function. The logic is to make a transgenic mouse with a toxin gene (often known as diphtheria toxin) under control of a specialized promoter which activates only in the target cell type. When the embryo development progresses to the point where it starts to form the target tissue, the toxin gene is activated, and that particular tissue dies. Other tissues are not affected.
Many disease states are heralded by changes in the blood count Leukocytosis can be a sign of infection. Thrombocytopenia can result from drug toxicity. Pancytopenia is ge
Q. What are cerebrovascular accidents? The Cerebrovascular accident (CVA), as well known as stroke, is the generic name given to infarction (tissue and cellular death by hypoxi
What is the Rh factor? The RH factor is a protein of the red blood cell plasma membrane that behaves as antigen in blood transfusions triggering a humoral (antibody-based) immu
Q. Stress Testing after Myocardial Infraction? Many post infarction deaths are sudden and occur with in the first 6 months after infarction. Exercise testing from 10 days to we
What is Transportation of Sick Newborn Infants with Heart Disease Communication : The decision to transport a newborn to a tertiay referral centre with facilities for specia
Q. What is the structural depiction of a carboxyl group? Carboxyl groups have a carbon attached to one hydroxyl group by a simple bond and one oxygen by a double bond. The othe
Light and Heavy Soils The presence of silt and especially clay in a soil imparts to it a fine texture, and a slow water and air movement. Such a soil is highly plastic becoming
Assessment While assessing the patient with rheumatic fever, a detailed history including, problematic environmental factors or recent exposure to streptococcal infection is
notes on butterfly
How is the genetic determination of sex established in humans? In the diploid genome of the human beings, there are 46 chromosomes, 44 of them are autosomes and two are sex chr
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