Ablation experiment, Biology

Assignment Help:

Ablation experiment is an experiment designed to produce an animal deficient in one or the few cell types, in order to study cell lineage or the cell function. The logic is to make a transgenic mouse with a toxin gene (often known as diphtheria toxin) under control of a specialized promoter which activates only in the target cell type. When the embryo development progresses to the point where it starts to form the target tissue, the toxin gene is activated, and that particular tissue dies. Other tissues are not affected.


Related Discussions:- Ablation experiment

Oxygen - factors influencing functions of nitrogenase, Oxygen - Factors Inf...

Oxygen - Factors Influencing Functions of Nitrogenase Oxygen is a strong inhibitor of N 2 -fixation because it blocks both the synthesis as well as the activity of nitrogenase

Tools of lower paieolithic age, Tools of lower paieolithic age Pleistoc...

Tools of lower paieolithic age Pleistocene times there were huge herds of very large mammals. Bones of such large mammals were found associated with the human fossil finds and

Acute complications of diabetes mellitus, Various acute complications of di...

Various acute complications of diabetes mellitus are described in this unit. Acute complications develop within a short period of time. These are due to improper treatment of diabe

What are the symptoms of acute pericarditis, Q. What are the Symptoms of ac...

Q. What are the Symptoms of acute pericarditis? Chest Pain Chest pain is the most important symptom. It is retrosternal in location and patient usually locates the site o

How aggregation occur in sickle-cell anemia, How does aggregation occur in ...

How does aggregation occur in sickle-cell anemia? Place the steps in the correct order from no aggregation to sickle red blood cell. Note that deoxyhemoglobin is generally in the T

Glycolipids, G L YCOLIPIDS They are lipids having sugar residues. ...

G L YCOLIPIDS They are lipids having sugar residues. Two common glycolipids are cerebrosides and gangliosides. (1) Cerebrosides They are made of amino alcohol sphi

Why ups is so important to health practitioners, Give a short explanation o...

Give a short explanation of what UPS really means and why it is so important to health practitioners and consumers/patients.

Difference between an ecological niche and a habitat, What is the differenc...

What is the difference between an ecological niche and a habitat? An ecological niche is a set of peculiar activities, resources and methods that a species explores to survive

Littoral and benthic zone, Littoral and Benthic Zone Littoral Zone ...

Littoral and Benthic Zone Littoral Zone This is the shallow water zone, near the shore, where light penetrates to the bottom. Rooted plants can grow only in this region.

Give an account of attenuated vaccines, Question 1 Write short note on ...

Question 1 Write short note on inflammatory response 2 Give an account of attenuated vaccines 3 What is innate immunity? Explain its characteristic features 4 What adjuvants? E

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd