Ablation experiment, Biology

Assignment Help:

Ablation experiment is an experiment designed to produce an animal deficient in one or the few cell types, in order to study cell lineage or the cell function. The logic is to make a transgenic mouse with a toxin gene (often known as diphtheria toxin) under control of a specialized promoter which activates only in the target cell type. When the embryo development progresses to the point where it starts to form the target tissue, the toxin gene is activated, and that particular tissue dies. Other tissues are not affected.


Related Discussions:- Ablation experiment

Role of private sector in health care - contracting, Role of Private Sector...

Role of Private Sector in Health Care - Contracting The government can transfer some of its work to the private sector by contracting. If the cost of resultant services (inclu

Define the energy requirement to avoid underweight problem, Define the Ener...

Define the Energy requirement to avoid Underweight problem? The total calorie intake should be 500 to 1000 Kcal in excess of the daily needs in order to result a gain in weight

What are anteromedial aspects of temporal lobes, Q. What are anteromedial a...

Q. What are anteromedial aspects of temporal lobes? Olfactory Cortex - found in anteromedial aspects of temporal lobes receive sensory information directly from the olfactory n

Determine the term - essential element, Determine the term - essential elem...

Determine the term - essential element It becomes difficult to meet all the conditions so as to establish essentiality. This is particularly so for the elements that are requir

Essay, Need an essay for my biology class. Need to know if you can do it. ...

Need an essay for my biology class. Need to know if you can do it. Thank you Instructions. Essay Assignment: Experimental Design Now that you have completed several hands-on la

Explain the types of care of teeths, Explain the types of care of teeths ...

Explain the types of care of teeths a) Plastic/ Nylon  Scalers: These are available in a variety of shapes and are moderately effective in calculus removal. Can be Ultrasonic

The km for an enzyme is equal to kcat, The Km for an enzyme A. is equal ...

The Km for an enzyme A. is equal to kcat, measured at low substrate concentration. B. is the substrate concentration that gives a velocity that is half the maximum velocity.

Explain the sinus perforations, Sinus Perforations  The maxillary antru...

Sinus Perforations  The maxillary antrum can sometimes be inadvertently penetrated. Through careful pre-operative planning using radiographs, including axial scans, this compli

Which hormones secreted by adrenal medulla, Q. What are the hormones secret...

Q. What are the hormones secreted by the adrenal medulla? What are their respective functions? The medullary portion of the adrenals secretes hormones of the catecholamine grou

Reviews - assurance engagements, Reviews - Assurance engagements The o...

Reviews - Assurance engagements The objective of financial statements of a review is to enable an auditor to state where, on the essential of procedures that do not give all t

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd