Ablation experiment, Biology

Assignment Help:

Ablation experiment is an experiment designed to produce an animal deficient in one or the few cell types, in order to study cell lineage or the cell function. The logic is to make a transgenic mouse with a toxin gene (often known as diphtheria toxin) under control of a specialized promoter which activates only in the target cell type. When the embryo development progresses to the point where it starts to form the target tissue, the toxin gene is activated, and that particular tissue dies. Other tissues are not affected.


Related Discussions:- Ablation experiment

Buffalo-pox, Buffalo-pox The disease is caused by an orthopox virus, c...

Buffalo-pox The disease is caused by an orthopox virus, closely related to the vaccinia virus. It is not clear whether it should be considered a separate virus or not. By RE m

Define and compare bone modeling and remodeling, Define and compare bone mo...

Define and compare bone modeling and remodeling Bone modeling is a surface-specific activity (apposition or resorption) that produces a net change in the sie and/or shape of a

Aspergillosis, Aspergillosis Aspergillosis is the most common chronic,...

Aspergillosis Aspergillosis is the most common chronic, granulomatous, necrotizing and cavitary disease of lungs, and is characterized by formation of white yellowish caseous

Explain complete and incomplete digestive system , Normal 0 fal...

Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4

What are the endocrine functions of the placenta, What are the endocrine fu...

What are the endocrine functions of the placenta? The placenta has endocrine function since it secretes the hormones progesterone and estrogen that maintain the endometrium (in

Explain metabolic requierments for types of exercise, Explain Metabolic Req...

Explain Metabolic Requierments For Types Of Exercise ? A relative scale of energy requirements related to heart function necessary for performing various daily activities has b

Three and four kingdom classification, Three and Four Kingdom Classificatio...

Three and Four Kingdom Classification The two-kingdom classification, while solving many of the problems of classification, failed to establish clear-cut distinction between p

Explain the fructo oligosaccharides (fos), Explain the Fructo Oligosacchari...

Explain the Fructo Oligosaccharides (FOS)? FOS are polymers of fructose, usually attached to an initial glucose molecule. The total number of fructose units range from 2 to 8 a

What are the two major types of endocytosis, Q What are the two major types...

Q What are the two major types of endocytosis? Endocytosis is the entry of material in the cell engulfed by portions of the cell membrane. Endocytosis can be classified as p

How can the hypothesis that asserts that chloroplasts, How can the hypothes...

How can the hypothesis that asserts that chloroplasts as well as mitochondria were primitive prokaryotes that associated in mutualism with primitive anaerobic eukaryotic cells be c

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd