Ablation experiment, Biology

Assignment Help:

Ablation experiment is an experiment designed to produce an animal deficient in one or the few cell types, in order to study cell lineage or the cell function. The logic is to make a transgenic mouse with a toxin gene (often known as diphtheria toxin) under control of a specialized promoter which activates only in the target cell type. When the embryo development progresses to the point where it starts to form the target tissue, the toxin gene is activated, and that particular tissue dies. Other tissues are not affected.


Related Discussions:- Ablation experiment

Explain coronary anatomy, Q. Explain Coronary Anatomy? The main coronar...

Q. Explain Coronary Anatomy? The main coronary trunks can be considered to lie in one of two orthogonal planes. The anterior descending and the posterior descending coronary ar

Determine about the brain tissue, Determine about the Brain tissue Bra...

Determine about the Brain tissue Brain tissue looks solid to the naked eye (it has a consistency of stiff jelly), so 'finger-grain' investigations had to await two technologic

Explain endonucleases, Explain Endonucleases Endonucleases  are  nucle...

Explain Endonucleases Endonucleases  are  nucleases present  in  the pancreatic juice like RNAase  andDNAase. These hydrolyze internal phosphodiester bonds which are located m

Define prevention of idd - double fortified salt, Define prevention of idd ...

Define prevention of idd - Double Fortified salt? iron deficiency anaemia and iodine deficiency disorders often co-exist, the most effective approach to control these public he

Preventive measures of rheumatic fever, Preventive Measure Primary p...

Preventive Measure Primary prevention Early detection and treatment of group "A" b-hemolytic streptococcal pharyngitis. Penicillin is the commonly prescribed drug. Educ

Discuss the principle of osmolarity, These labs discuss the principle of os...

These labs discuss the principle of osmolarity, which is defined as the total number of solute particles in 1 L of solution. Is this the same thing as tonicity? Explain your answer

Briefly describe the mechanism, List and briefly describe the mechanisms th...

List and briefly describe the mechanisms that prevent acid-base imbalances from appearing in the body. In addition, indicate where each mechanism functions most significantly.

Explain the precautions for sub-culturing of a culture, Explain the Precaut...

Explain the Precautions for Sub-Culturing of a Culture 1. Sterilization of inoculating wire before and after the transfer is a must. Sterilized wire should not be kept on labor

What is biotic potential, Q. What is biotic potential? The Biotic poten...

Q. What is biotic potential? The Biotic potential is the capability of growth of a given population under hypothetical optimum conditions, i.e., in an environment without limit

Swine-pox, Swine-pox Pigs of 2 months of age may be infected with vaccinia...

Swine-pox Pigs of 2 months of age may be infected with vaccinia either naturally or artificially and show pox lesions on the eyelids, snot, inside the thigh and undersurface of th

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd