Ablation experiment, Biology

Assignment Help:

Ablation experiment is an experiment designed to produce an animal deficient in one or the few cell types, in order to study cell lineage or the cell function. The logic is to make a transgenic mouse with a toxin gene (often known as diphtheria toxin) under control of a specialized promoter which activates only in the target cell type. When the embryo development progresses to the point where it starts to form the target tissue, the toxin gene is activated, and that particular tissue dies. Other tissues are not affected.


Related Discussions:- Ablation experiment

Tissue distribution and regulation of calcium concentration, Define Tissue ...

Define Tissue Distribution and Regulation of Calcium Concentration? As already discussed, development and preservation of bone mass is quantitatively an important function of c

Human respiratory system - alveoli, A L VEOL I - Sac like structu...

A L VEOL I - Sac like structure, unit of lungs. Increase surface area, exchange of gases occur in it. Rich in blood capillaries. Aloeoli join by pore of Kuhn to form a

Deficiency diseases-iodine deficiency, Iodine  deficiency Iodine is an...

Iodine  deficiency Iodine is an important component of thyroid hormones, which play active role in several physiological process such as control of basal metabolic rate, oxidat

What units are the nucleic acids constituted, Q. Of what units are the nucl...

Q. Of what units are the nucleic acids constituted? What are chemical entities that compose that unit? The Nucleic acids are formed by sequences of nucleotides. Nucleotides

How to investigate aortic stenosis by cardiaccatheterization, Q. How to inv...

Q. How to investigate aortic stenosis by Cardiac Catheterization? The indications are to confirm hemodynamics when the non-invasive tests are not conclusive or there is a disc

Long term potentiation, It is a neural mechanism that plays a role in encod...

It is a neural mechanism that plays a role in encoding of new information. Encoding takes place as a result of changes in the strength of synapses among neurons in neuronal network

Define hormonal and receptor proteins, Define Hormonal and Receptor Protein...

Define Hormonal and Receptor Proteins? Hormonal proteins : Hormonal proteins coordinate the bodily activities. Several peptide and protein hormones (like insulin and growth ho

When did life appear on earth?, When did life appear on earth? It is es...

When did life appear on earth? It is estimated that the life on earth emerged about 3.5 billion years ago, thus 1 billion years after the formation of the planet.

Name the two groups of nephrons, Name the two groups of nephrons on the bas...

Name the two groups of nephrons on the basis of their position in the kidney. How are they different from each other? a) How is the halophyte Rhizophora adapted to survive in i

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd