Ablation experiment, Biology

Assignment Help:

Ablation experiment is an experiment designed to produce an animal deficient in one or the few cell types, in order to study cell lineage or the cell function. The logic is to make a transgenic mouse with a toxin gene (often known as diphtheria toxin) under control of a specialized promoter which activates only in the target cell type. When the embryo development progresses to the point where it starts to form the target tissue, the toxin gene is activated, and that particular tissue dies. Other tissues are not affected.


Related Discussions:- Ablation experiment

Phylum labyrinthomorpha - protozoan, Phylum Labyrinthomorpha - Protozoan ...

Phylum Labyrinthomorpha - Protozoan Trophic stage, ectoplasmic network with spindle shaped or spherical nonamoeboid cells. Small group living on algae; mostly marine or estuar

Determine the lateral cephalometric skull view, Determine the Lateral Cepha...

Determine the Lateral Cephalometric Skull View The use of this modality is limited in preoperative evaluation in implant placement for advance cases where there is a need for b

Explain carbohydrates requirement during thyphoid, Explain carbohydrates re...

Explain carbohydrates requirement during thyphoid Carbohydrates: Carbohydrate intake should be liberal. This can be attributed  to: 1.  Repletion of glycogen stores. 2.

Determine the expected genotypic and phenotypic results, 1. In guinea pigs,...

1. In guinea pigs, black coat color (B) is dominant to white (b), and a rough coat (R) is dominant to smooth (r). What are the expected genotypic and phenotypic results of the foll

Define about the sterols - non glyceride fractions, Define About the Sterol...

Define About the Sterols - Non Glyceride Fractions? These constitule a major proportion of the non-glyceride component while tocopherols, carotene pigments and flavour compound

Carbohydrates, Carbohydrates are the next important nutrients as they have ...

Carbohydrates are the next important nutrients as they have to perform a variety of functions such as: 1) Provide major source of energy 2) Breakdown of fatty acids and preve

Controlling introduction of alien species, Controlling Introduction of Alie...

Controlling Introduction of Alien Species As you know the alien species can cause the existing population to decrease or even become extinct. The individuals of alien species

Interactions between minerals, Interactions between minerals Copper de...

Interactions between minerals Copper deficiency has been identified as a serious problem for grazing ruminants. A deficiency may be due to low concentrations of Cu in forage a

Determine about the halstead''s method, Determine about the Halstead's meth...

Determine about the Halstead's method Reitan adopted Halstead's methods and various test procedures and with them established a laboratory at the University of Indiana. He supp

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd