Why would expect to find the dna that has this mutation

Reference no: EM133335385

Assignment:

You discover that a muscle disorder that leads to weakness and lack of energy is associated with a mutation in the gene for ATP synthase (causing a change in the amino acid sequence of the protein). This impedes the diffusion of H+ across the mitochondrial membrane, reducing it but not stopping it.

a. Where would you expect to find the DNA that has this mutation? Why?

b. What part of ATP synthase would you expect the mutation to affect? Be sure to discuss how changes in the protein could lead to slower diffusion across the membrane.

c. As the concentration of H+ builds up and the ATP Synthase cannot keep up, you observe that the electron transport chain stops accepting NADH at protein 1. As the concentration of NADH in the mitochondria increases, how will the processes of the citric acid cycle be affected? Pyruvate processing?

Reference no: EM133335385

Questions Cloud

Concept of ecosystem services : One useful way to look at ecology from a human-centered viewpoint is the concept of ecosystem services.

What is the difference between sexism and heteronormativity : What is the difference between sexism and heteronormativity? Describe racism and race-based stereotyping, oppression, and discrimination. Why are various groups

Determine an organizational best practice : Determine an organizational best practice for a given company - Evaluate the companys efforts to handle diversification, integration, and decline

What do you think your training team should recommend : Given the current trends you have observed, what do you think your training team should recommend to address this growing problem? What do you think

Why would expect to find the dna that has this mutation : You discover that a muscle disorder that leads to weakness and lack of energy is associated with a mutation in the gene for ATP synthase.

Do you have a coaching session with amir : Do you have a coaching session with Amir? Do you orchestrate a formal counseling notice with Amir? Do you put him on a final warning? Do you terminate Amir?

What is the role of hr in shaping organizational culture : What is the role of HR in shaping organizational culture that prioritizes these broader social issues? Your answer should include specific connections to course

Evaluate the level of impact that the identified factors : Outline a communication system that will have the greatest impact on improving employee motivation, and specify the major reasons

How is dna used in the development of gene targeted drugs : How is DNA used in the development of gene targeted drugs? Provide examples of two specific drugs in this area of development.

User Account

All Pages