Why was the frequency of cytotoxic

Assignment Help Biology
Reference no: EM131900977

Derive an original research question from this passage:

"Since cytotoxic CD4+ T cells preferentially eliminated MHC II-ex- pressing CD19+ cells, why was the frequency of cytotoxic CD4+ T cells positively correlated with the frequency of MHC II-expressing CD19+ cells? One possibility is that the development of tumor-reactive cyto- toxic CD4+ T cells requires an abundance of MHC II-expressing tumor cells. Also, since the study was performed in an in vitro condition, it is unlikely to capture all the complexities of an in vivo system. In the human body, the MHC II-expressing CD19+ cells may be quickly re- plenished via proliferation. In addition, it was found that IL-10-ex- pressing CD4+Foxp3- Tr1 cells could produce granzymes and perforin and therefore, in our experimental system, the cytolytic molecule-ex- pressing Tr1 cells could not be distinguished from other cytotoxic CD4+ T cells. "

Reference no: EM131900977

Questions Cloud

Create a paper on key turning points in political history : Create a 5-6 page paper on Key Turning Points in Political History. You will be required to draw from at least 3 secondary sources to inform their approach.
Anatomy and functions of the plasma membrane : Please explain the anatomy and functions of the plasma membrane? What are is it mainly composed of?
Rewrite the synthesis paper on the given topic : Rewrite the synthesis paper on the given topic. Your response should be typed, double-spaced. All sources used, including the textbook, must be referenced.
Pricing structure for radiology on per-procedure basis : You have been asked to establish a pricing structure for radiology on a per-procedure basis.
Why was the frequency of cytotoxic : Since cytotoxic CD4+ T cells preferentially eliminated MHC II-ex- pressing CD19+ cells, why was the frequency of cytotoxic CD4+ T cells
Write about all the concerns that you will face : You create a Brazilian website. Write about all the concerns ( social, economics, governement, etc...) you will face( one page is enough).
How you would determine the appropriate measurements : How you would determine the appropriate measurements and strategic drivers to assess annually?
Analyse the foreign direct investment policy : Analyse the The political, economic and legal systems and the Foreign Direct Investment policy in relation to your product .
What is meant by the term biology : What is meant by the term biology? Who first coined the term?

Reviews

Write a Review

Biology Questions & Answers

  Immune response to infectious disease

It is a very curcial concept to understand how the immune response is mounted against viruses, bacteria, protozoans and helminthes. For an effective immune response, both innate and adaptive immunity should work together.

  A review on advanced glycated end products (ages)

This Project report elaborates a critical review of important elements attached to Advanced Glycated End Products (AGEs). It is very crucial to understand the process called Millard reaction.

  Plastic as a soil stabilizer

Soil stabilization is the permanent physical and chemical alteration of soils to enhance their physical properties. Stabilization can increase the shear strength of a soil and control the shrink-swell properties.

  Principles of microbiology

This assignment has three parts which contains questions related to Microbiology. It contains basic principles of microscopy, staining techniques in microbiology and microbial growth in the food industry.

  List the biologic functions

Lipid metabolites are often seen as key elements in cellular signaling. Is this unique? Please provide several examples of the function of lipids as key elements in signal arrays and list the biologic functions these signals affect?

  Biologic function relationships

Please describe how one might search for chemical structure, biologic function relationships, involving small molecular weight lipophylic compounds. Provide one example.

  Case study on patient in the haematology laboratory

Write a case study which detailing a scenario of a patient being investigated in the Haematology laboratory.

  Use of pcr and genetic approaches in biotechnology

The use of PCR and genetic approaches in biotechnology

  Describe the role of this enzyme in honey

Glucose oxidase is an enzyme that can be used for measurements of glucose levels by combining this reaction with an oxygen probe.

  Genetic problems

What phenotypic ratio would you get if you crossed a white mouse and a heterozygous brown mouse?

  Prepare an essay on nosocomial infection

Prepare an essay on nosocomial infection.

  Monitoring and recording the blood pressure

To increase the awareness of monitoring and recording the blood pressure of patients and practice measuring blood pressure in a safe environment.

Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd