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A drug swallowed as a pill or capsule may not make it into the general circulation in sufficient amounts to be effective. Explain different mechanisms that may account for this observation. Why might a drug delivered by a skin patch or nasal spray be more effective than the same drug taken orally?
You've developed a new Alzheimer's drug that disrupts the abnormal amyloid pathway that results in Alzheimer's disease. In its current formulation, the octanol/water partition coefficient of your drug is quite low, completely lipophobic. Why won't..
Consider a species of dinosaurs and assume that females are XX and males are XY. Further assume that black scales, B, is a sex-linked dominant trait and that green scales, b, is the recessive trait. The gene resides on the X gene only.
Describe the structure and function of the three forms of RNA determine the primary structure of polypeptide chains during translation.
During a cross between organisms having genotypes of AaBbCc and AaBbcc, what proportion of the offspring would be expected to be aaB_Cc?
A volume of aqueous hydrochloric acid containing 0.500 mol of HCl and 0.100 mol of magnesium metal were combined and reacted to completion. How many liters of hydrogen gas were produced under STP conditions?
What carries genes for antibiotic resistance in prokaryotes?
describe the basic properties of DNA that are responsible for fiber formation when alcohol is added to solution that contains DNA?
How does changing the pH or temperature of a reaction affect the active site of an enzyme?
In a series of experiments, genes that code for mutant forms of a receptor tyrosine kinase are introduced into cells. The cells also express their own normal form of the receptor from their normal gene.
Assume you learned in class that DeltaG for compete oxidation of glucose is -686kcal/mole. According to the DeltaG for ATP and the numbers of ATP,
Diagram and explain how xylem sap & phloem sap are transported in plants. There are several diagrams in the book showing different parts of the overall process.
An SDS-PAGE gel is run of proinsulin and insulin.Samples were treated with beta-mercaptoethanol prior to electrophoresis.Draw a picture of the predicted results.
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