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Question: Why is oral phenylephrine so useless? [ 1 It is extensively metabolized, starting in the gut wall. ] [ 2 You can find a bioavailability figure of 38% in the literature, but that appears to be the most optimistic number possible,] and [3 you can also find studies that show 1% or less.] Overall, [4 the Cmax is highly variable patient-to-patient], and [5 the lack of cardiovascular effects at low doses argues for very low systemic effects (and expected low efficacy as a decongestant).] [ 6 The bioavailability increases at higher doses as you apparently saturate out some of the metabolic pathways,but at the 10mg dose typically used for decongestants, you can forget it. ]
The restriction enzyme Scs1 cuts at a restriction site that is found only very rarely in dog genomes. One dog, Jimmy, has two restriction sites for this restriction enzyme in his genome. Another dog, Billy, has three restriction sites for this enz..
How does the research contribute to nursing knowledge? in A cross sectional study: Patient privacy according to doctors and nurses by Nilufer Demirsoy
The article "Acupuncture for Bad Backs: Even Sham Therapy Works" (Time, May 12, 2009) summarized a study conducted by researchers at the Group Health
Explain how the process is performed. Elaborate on an ethical concern, such as leftover embryos, DNA privacy, or mandated vaccines.
What is the difference between and haploid number and a ploidy number, and how do you determine them?
What would be the long term effects on not being able to control muscle contraction - How might the technology associated
Why is the benefit of having different codons that can code for the exact same amino acid?
What band(s) would be expected if subjected to ultracentrifugation through a CsCl gradient?
In Tomatoes, the allele for red fruit is dominant over the allele for yellow fruit. The allele for tall plants is dominant over the allele for short plants.
Explain the basic structure and function of proteins. Include the primary and tertiary structures and the differences between structural and functional
A thirty-five year old man has been brought in to the hospital with severe vomiting, diarrhea, abdominal cramping, and bradycardia.
The ABO blood group assorts independently of the Rhesus (Rh) blood group and the MN blood group. Three alleles, IA , IB , and i, occur at the ABO locus.
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