Why is ibuprofen not a good substitute for aspirin

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Reference no: EM133494037

Using information gleaned from your readings on Eicosanoids, give a clear biochemical responseto these questions (Your answers should not be more than 2 pages):

Question a. A 65 year old retired construction worker is referred to the dialysis clinic following arecent diagnosis of chronic kidney disease due to a prolonged use of of the NSAIDIbuprofen. Explain the biochemical basis of NSAID nephropathy?

Question b. What is the biochemical rationale for the use of low dose aspirin in patients withcoronary artery disease? Why is Ibuprofen not a good substitute for aspirin in thiscase?

 

Reference no: EM133494037

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