Why enzyme perform such selective on different substrates

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Reference no: EM1396314

RNA Polymerase does not have a 3' to 5' exonuclease activity AND it doesnt need one. (true or false, explain) [i think it's false. i came across this information, but im not sure if i am reading it correctly. The 3'-to-5' exonucleolytic decay and processing of a variety of RNAs is an essential feature of RNA metabolism in all cells. The 3'-5' exonucleases, and in particular the exosome, are involved in a large number of pathways from 3' processing of rRNA, snRNA and snoRNA, to decay of mRNAs and mRNA surveillance. The potent enzymes performing these reactions are regulated to prevent processing of inappropriate substrates while mature RNA molecules exhibit several attributes that enable them to evade 3'-5' attack. How does an enzyme perform such selective activities on different substrates? The goal of this review is to provide an overview and perspectives of available data on the underlying principles for the recognition of RNA substrates by 3'-to-5' exonucleases. any input is much appreciated.

Reference no: EM1396314

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