Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
Question 1 of 5 Why does SRP arrest translation after it binds to the signal sequence and only the first 70 amino acids of the protein have been synthesized? A. Most secretory proteins are only 70 amino acids long (7 kDa) so translation is completed by the time SRP binds. B. SRP arrests translation to allow the exposed signal sequence to be cleaved from the protein before it enters the translocon. C. SRP arrests translation so the signal sequence is not misfolded within the interior of the protein. D. SRP does not arrest translation. The SRP receptor arrests translation after SRP docks the ribosome and newly synthesized protein on the ER. Question 2 of 5 What is the purpose of GTP hydrolysis when SRP binds to the SRP receptor? A. It's a source of energy to allow protein synthesis to resume. B. It causes SRP to dissociate from the signal sequence, ribosome and SRP receptor. C. It "hands off" the ribosome to the translocon D. (a) & (b) E. (b) & (c) Question 3 of 5 How does a single P54SRP bind to diverse ER signal sequences that do not have identical amino acid sequences? A. Multiple D & E on P54SRP form electrostatic bonds with "core" K & R present on all signal sequences. B. Multiple K & R on P54SRP form electrostatic bonds with "core" D & E present on all signal sequences. C. Multiple polar amino acids on P54SRP form hydrogen bonds with "core" polar amino acids present on all signal sequences. D. Cells have multiple isoforms of P54SRP that interact specifically with distinct ER signal sequences. E. Multiple hydrophobic amino acids on P54SRP form van der Waals interactions with "core" hydrophobic amino acids present on all signal sequences. Question 4 of 5 The membrane spanning α-helix of a type I integral membrane protein such as the LDL receptor or Glycophorin A: A. Is referred to as an "internal signal anchor" and ensures that the N-terminal portion of the protein that precedes it will be inserted into the ER lumen and the C-terminal portion of the protein that follows it will remain in the cytosol. B. Is referred to as an "internal signal anchor" and ensures that the N-terminal portion of the protein that precedes it will remain in the cytosol and the C-terminal portion of the protein that follows it will be inserted into the ER lumen. C. Is referred to as an "stop-transfer anchor" and ensures that the N-terminal portion of the protein that precedes it will be inserted into the ER lumen and the C-terminal portion of the protein that follows it will remain in the cytosol. D. Is referred to as an "stop-transfer anchor" and ensures that the N-terminal portion of the protein that precedes it will remain in the cytosol and the C-terminal portion of the protein that follows it will be inserted into the ER lumen. Question 5 of 5 You're studying the Na+/K+ ATPase in a certain cell line. (Remember, it's present in virtually all cells so the particular cell type doesn't matter here). You have 4 samples of these cells that have identical #s of Na+/K+ ATPases. Sample 1 are the control cells that are not treated with anything. They retain 100% Na+/K+ ATPase activity throughout the experiment. Sample 2 is treated continuously with a sufficiently high dose of the cardiac glycoside oubain that you see 100% inhibition of Na+/K+ ATPase activity 6 hours later in the oubain treated cells. 100% Na+/K+ ATPase activity is still inhibited 12 hours later. Sample 3 is treated continuously with a sufficiently high dose of an siRNA that completely degrades the mRNA encoding the α subunit of the Na+/K+ ATPase in less than 30 minutes. However, you observe that only 50% of Na+/K+ ATPase activity is inhibited 6 hours later in the siRNA-treated cells even though all the α subunit mRNA has been degraded. Only 25% of Na+/K+ ATPase activity remains 12 hrs after siRNA treatment. Sample 4 is treated continuously with a sufficiently high dose of the general protein synthesis inhibitor, cycloheximide. However, you observe that only 50% of Na+/K+ ATPase activity is inhibited 6 hours later in the cycloheximide-treated cells even though all protein synthesis has been inhibited. Only 25% of Na+/K+ ATPase activity remains 12 hrs after cycloheximide treatment. What can you conclude from this experiment? A. siRNA and cycloheximide only partially inhibit Na+/K+ ATPase activity. B. oubain completely inhibits both Na+/K+ ATPase activity and its synthesis. C. Oubain completely inhibits Na+/K+ ATPase synthesis but not its activity. D. The half-life of the α subunit protein is 6 hrs. E. You cannot conclude anything from this experiment.
Which of the following are secondary sex characteristics in females?
What sequence of nucleotide pairs in a Drosophila gene will encode the amino acid sequence met-trp-phe-trp-met (reading from the amino terminus to the carboxyl terminus)?
Explain why a deficiency either of vitamin B12 or of folate causes red blood cells to be larger than normal.
describe structural and functional adaptations that appeared in early amniotes that foreshadowed the mammalian body plan.
What are some possible functions of MMR effectors (
Which is easier to dispose of in a flock of chickens? A recessive allele for erect combs or a dominant allele for feathered legs. How various generations would it take.
Breathing Rate increasesas Power raise. However, it is not expectedto increase linearly throughout the Power domain. Explain how BR increased as Power increased
Although each of the following has a better chance of influencing gene frequencies in small populations than in large populations, which one most consistently requires a small population as a precondition for its occurrence?
What are some of the major functions of the bacterial capsule? What is unique about the Bacillus anthracis capsule that makes the bacteria so lethal?
Discuss how does the toxicity of microbial agents affect the human body and how efficient are synthetic agents and how are they used in medicine?
A plasmid digest with BamHI produced 2 kb and 4 kb fragments. Digest of a plasmid with HindIII produced 6 kb fragment. Double digest with both enzymes produced 1 kb, 2 kb and 3 kb fragments. Sketch a plasmid map.
explain how the terms "ancestral" and "derived" differ from the terms "gained" and "lost." How can you have a character that is lost, but is the derived state of that trait?
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +1-415-670-9521
Phone: +1-415-670-9521
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd