Which type of synapse, an axodendritic or an axosomatic

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1. Which presynaptic molecule is the sensor for Ca2+?

2. There are two different types of ionotropic glutamate receptors, AMPA and NMDA receptors. NMDA receptors have a higher affinity, that is a lower EC50, for glutamate than AMPA receptors. All other things being equal, which receptor would most likely be saturated by a glutamate release event?

3. What would be the post-synaptic potential (PSP), on average, if one had 10 release sites (N), a release probability (Pr) of 0.6, and a quantal size (q) of 0.5 mV? The quantal size (q) is the amplitude of a unitary release event.

4. If GABAergic synapse A has 10 GABAA receptors and GABAergic synapse B has 20 GABAA receptors, which synapse would show a larger post-synaptic potential (PSP) in response to a release event?

5. Presynaptic terminal A has 10 voltage-gated Ca2+ channels (Cav). Presynaptic terminal B has 15 Cav. All other things being equal, which presynaptic terminal would have a higher release probability (Pr)?

6. All other things being equal, which type of synapse, an axodendritic or an axosomatic, would have the greatest effect on the postsynaptic cell firing an action potential?

Reference no: EM133663223

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