Reference no: EM132767732

Remdesivir

a. Remdesivir absorbs strongly in the UV (Amax - 260 nm). Show on the structure above the chromophore of remdesivir

b. Remdesivir is not significantly fluorescent. Which of the following ranges characterizes its fluorescence quantum yield?

0 to 0.2
0.2 to 0.4
0.4 to 0.6
0.6 to 0.8
0.8 to 10

c. As an adenosine analog, the major pathway for the excited state relaxation of remdesivir is external conversion. Please name two approaches that could be expected to improve the fluorescence of remdesivir.