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A stock homozygous for three recessive autosomal genes, a, b,and c, not necessarily linked on the same chromosome, ismated to a stock homozygous for their dominant wild-typealleles. F1 females are then backcrossed to males of thehomozygous recessive parental stock and the following cross results are observed:
Phenotype Number Phenotype Number
a bc 42 a b+ 6
+ ++ 48 + +c 4
a ++ 46 a +c 5
+ bc 44 + b+ 5
1. Which of these genes are linked?
2. What is the recombination frequency between the linkedgenes?
What does the cell use NAD+ and NADP+ for? What is the difference between the two? In what types of biological pathways is NAD usually used in? NADP?
A solution of the potent insomnia drug Verless must be prepared immediately before use. How many grams of Verless do you need to make 10 mls of a 100 mM solution given that the molecular weight of Verless is 100 g/mole?
Why can prakaryotes quickly re infect a patient if they are not wiped out? How may this result in the evolution of drug resistant pathogens.
Why scientific method is used in medicine? What characteristic or property of experimental design is the most crucial for medical research?
With respect to the case-control studies compare the usefulness of the hospital and neighbourhood (community) controls. Your comparison must involve a comparison of the cost, feasibility, co-operation of the controls, recall bias, selection of contro..
Hulton Getty, London. Massie, Robert K. Nicholas and Alexandra. Pedigree for hemophilia A in European royal houses. How would you understand this inheritance pattern.
Draw a biomechanical force diagram for the flexor carpi radialis muscle. Label the fulcrum, bones used as levers, force application point, and the resistance. What kind of lever system does this represent?
What is the significance, while setting threshold for adverse effects, of the fact that, broadly speaking, solid particulates have much longer biological half times than gases and vapours.
At room temperature, equilibrium potential of K+ in a cell with internal concentration of K+ 10 fold higher than that of external concentration will be approximately.
If the experimental animals in a chamber were engaged in physical activity, how would this change the results of metabolism experiment.
An individual heterozygous for 4-gene pairs AaBbCcDd was testcrossed to aabbccdd , and progeny were classified as follows,
Assume you examine the stability of your favorite protein kinase and find that half of the protein is degraded every 10 minutes.
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