Which of the statements about immature naïve b cells

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Which of the following statements about immature naïve B cells that have been released from the bone marrow is not true?

a. They express both IgM and IgD.
b. They must acquire access to secondary lymphoid tissue in order to survive beyond a few days.
c. They readily form plasma cells in the blood circulation without help from other cells.
d. Since they have survived the negative selection process in the bone marrow, these B cells are guaranteed to be tolerant to self tissues.

Reference no: EM13155420

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