Reference no: EM133275843
Question - Define the following: selective toxicity, therapeutic index, side effect, narrow-spectrum drug, broad-spectrum drug, synthetic and semisynthetic antibiotics, cidal and static agents, minimal inhibitory concentration, and minimal lethal concentration.
Which drug would have more side effects: a drug with a high or low therapeutic index? How is this related to Ehrlich's notion of a magic bullet?
How can the MIC and MLC concepts be applied to distinguish between cidal and static agents?
Specific Tests Can measure Antimicrobial Activity
You might want to pay particular attention to this discussion as you will be performing a Kirby Bauer test in Week 9 in lab.
Describe the relationship between the diameter of growth inhibition and antibiotic susceptibility in the Kirby-Bauer test.
What would you surmise if you examined a Kirby-Bauer assay and found individual bacterial colonies growing within the zone of inhibition?
How is the Etest carried out? When might it be used instead of the Kirby-Bauer test?
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