What will happen to the erk phosphorylation

Assignment Help Science

Reference no: EM133478871

Assignment:

The A549 cell line contains a Gly12Ser variant in KRAS.

1. How does this variant affect intracellular signalling and ERK phosphorylation.

2. What will happen to the ERK phosphorylation, if it contains the variant.

3a. What pathway is activated by KRAS?

3b. How might this pathway be impacted by changes in the DNA sequence of the KRAS gene?

Reference no: EM133478871

Questions Cloud

What are two ways that urbanization might impact the region : Sub-Saharan Africa has one of the highest rates of Urbanization in the world. What are two ways that urbanization might impact the region?

Create a post describing active theory of aging : Create a post describing Active theory of aging that you found to be the most interesting, and relevant to understanding how we understand aging.

Discuss the use of mesenchymal cells in cell therapy : Define mesenchymal stem cells in the context of organismal development. Discuss the use of mesenchymal cells in cell therapy and tissue engineering.

What is the probability that a ucu sequence will occur : What is the probability that a UCU sequence will occur? (Answer up to one decimal place. Write % sign in the answer).

What will happen to the erk phosphorylation : How does this variant affect intracellular signalling and ERK phosphorylation. What will happen to the ERK phosphorylation, if it contains the variant.

How mendels interpretation of his pea plant experiments : Explain how Mendel's interpretation of his pea plant experiments would have changed if he did not use pure breeding, homozygous genotypes in his P1 generation.

Explain evolutionary terminology : Explain, using evolutionary terminology and concepts, how the ancient male peacock (dull, grey bird with small feathers) became the modern-day peacock?

What will the frequency of the aa genotype be : What will the frequency of the AA genotype be? What will the frequency of the Aa genotype be?

What are some of the challenges faced by widows : What are some of the challenges faced by widows? What are the differences between Men and Women when losing a spouse?

User Account

All Pages