Reference no: EM133450761
Case Study: A group of researchers are conducting a study to determine the effectiveness of a new COVID-19 vaccine. They contacted 50,000 individuals (20,000 men, 30,000 women) to participate in the trial. As part of their screening, they identified 2,400 individuals (1,000 men, 1,400 women) who tested positive for COVID-19. The remaining subjects entered the trial and were equally divided into vaccine and placebo groups, with an equal number of men and women in each group. Of those in the vaccine group, 20 (8 men, 12 women) contracted COVID-19 after 1 year of follow-up while 800 (500 men, 300 women) contracted COVID-19 during the same period in the placebo group. (Clue: Describe these rates as per 1,000 persons)
Questions:
- What type of study design is described here?
- Calculate the incidence of COVID among women and men during study. Which group is at greater risk of catching COVID, and how much greater is their risk? (Hint: cumulative incidence rates and risk ratios)
- Calculate the incidence of COVID among those who received the vaccine and those who received the placebo during study. Which group is at greater risk of catching COVID, and how much greater is their risk?