Reference no: EM133423578
Questions:
1. Summarize what the author means by "long-term implications" and "short-term effects" of gene duplication.
2. What is a paralagous gene?
3. What is the goal of the paper?
4. Describe the redundancy model that the author attributes to Ohno (1970).
5. Why is it important to understand dosage of duplicate genes when studying adaptive evolution through gene duplication
6. Which type of selection is likely to lead to the fixation of a gene duplicate in the genome?
Positive selection
7. Explain how examining the ratio of nonsynonymous to synonymous mutations (dN/dS) allows us to infer whether a duplicate is under positive or negative selection.
8. Summarize the first paragraph of section (d). What are the key points in this section?
9. How is gene duplication involved in drug resistance?
10. Summarize the three generalizations regarding when adaptive duplication may be expected to play a role in adaptive evolution.