What specimen types are appropriate for ihc analysis

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Problem

A 42-year-old woman with a prolonged history of gastroesophageal reflux disease presents with recent postprandial vomiting. Computed tomographic scan of the abdomen shows no diagnostic abnormalities. Upper gastrointestinal endoscopic evaluation reveals an incidental 1-cm submucosal duodenal mass clinically concerning for a gastrointestinal stromal tumor (GIST). Direct smears show partially cohesive epithelioid cells with vesicular chromatin, rare nucleoli, minimal granular cytoplasm, and no evidence of mitoses, necrosis, or stroma. A cell block preparation shows no definitive lesional tissue present across multiple deeper levels. What specimen types are appropriate for immunohistochemical (IHC) analysis?

Reference no: EM133727611

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