Reference no: EM133584185

Question: A 2-year-old male presents in the urgent pediatric care with a 6-hour history of fever, cough, and shortness of breath. Upon examination, the patient has a dry, unproductive cough and a temperature of 99.8°F (37.6°C). Laboratory tests reveal a lack of IgG and IgA antibody isotypes, though IgM values are normal. The number of T, B, and NK cells are also normal. The child is diagnosed with Pneumocystis jivorcii pneumonia, and is evaluated and confirmed to have CD40L deficiency, the most common form of immunodeficiency leading to the observed clinical signs. What mechanisms of type 1 immunity would remain intact in this patient? Intact Type 1 Immunity Mechanisms Activation of cytotoxic CD8+ T cells Initiation of the germinal center reaction TH1 cell secretion of IFN-γ NK cell cytotoxicity through death receptors Granuloma formation Defective Type 1 Immunity Mechanisms