What kind of immunodeficiency these children might have

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ECG (Bacillus Calmette-Guerin) is a live attenuated strain of tuberculosis that is used in many countries to immunise against infection with M. tuberculosis. In very rare instances: the vaccine produces a disseminated infection that affects many organs; this generally occurs because the recipient of the vaccine is immunodeficient or immunosuppressed.

it is found that a girl and a boy, from a family of ?ve children, have developed a disseminated infection with BCG following vaccination; it is suspected thatthese children are immunodeficient.

Comment on what kind of immunodeficiency these children might have, and how it prevents the immune system from controlling infection with BCG. Your explanation should be based on understanding how the immune system controls infections caused by mycobacteria.

Reference no: EM133432383

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