What is the volume of distribution-half-life

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Reference no: EM133381651

Assignment:

Student question

This is my 3rd time posting this question. The previous 2 times gave me different answers each time, and they were not the same as the answers provided by the examination board. The correct answers are posted below. I need help in figuring out how the correct answers are obtained.

A patient was administered Drug X at 80 mg iv bolus every 12 hours for an infection. After 3 days of treatment, drug levels were determined immediately prior (pre) and immediately after (post) a dose. The plasma levels were:

Pre: 1 mg/ml, Target peak: 7.5 mg/L

Post: 5 mg/ml, Target trough: 2.5 mg/ml

What is the Volume of distribution, half-life and clearance of Drug X in this patient?

Reference no: EM133381651

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