What is the type of inheritance for this disease

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Reference no: EM133290549

Assignment:

Questions:

1. What is the connection between the UV- sensitive phenotype of the m1 yeast cells and the ERCC5/XP-G human gene?

2. What is the type of inheritance for this disease? Autosomal recessive

3. What are the two top hits for the clinical skin issues for the disease?

4. Which yeast gene was disrupted by the transposon in mutant m2?

5. Is the function of this yeast gene known? If so, summarize what is known.

6. What is the top significant alignment in humans? (Blast @ NCBI).

7. What protein does it encode? Single-stand specific DNA endonuclease.

8. When this human protein is defective, which human disease occurs? In which complementation group?

Reference no: EM133290549

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