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Assignment:
Questions:
1. What is the connection between the UV- sensitive phenotype of the m1 yeast cells and the ERCC5/XP-G human gene?
2. What is the type of inheritance for this disease? Autosomal recessive
3. What are the two top hits for the clinical skin issues for the disease?
4. Which yeast gene was disrupted by the transposon in mutant m2?
5. Is the function of this yeast gene known? If so, summarize what is known.
6. What is the top significant alignment in humans? (Blast @ NCBI).
7. What protein does it encode? Single-stand specific DNA endonuclease.
8. When this human protein is defective, which human disease occurs? In which complementation group?
Compare the processes of independent assortment and crossing over. Which process has the greatest influence on genetic diversity?
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Proteins within most living organisms are comprised of 20 amino acids encoded for by the nearly universal genetic code found within nature.
Consider you could micro-inject the cytochrome c within the cytosol of the wild-type cells and of cells which were doubly defective for Bax and Bak.
Assume you have a bacterial suspension and you need to dilute it to .0010 of the initial concentration so that you can determine thenumber of colonies per milliliter.
Why do you think parasites like trematodes produce such large quantities of eggs?
Elegans with the mutation sma-2 results in a mutant phenotype characterized by small body size. You place a hermaphrodite that is homozygous for sma-2 and a hermaphrodite that is homozygous wile-type (+) on a single plate. Monohybrid Crosses: Crosse..
Create a TWO major groups of genes that when mutated can cause canceroncogenesproto-oncogenestumor-suppressor genes
2-types of signals have been implicated in metaphase checkpoint arrest. Think about the results of a recent experiment in which the unattached kinetochore of a monoattached chromosome was destroyed by a laser beam.
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