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A patient affected with B-thalassaemia was tested for the known thalassemia mutations, however none of the known mutations was detected. Therefore, a blood sample was sent to the molecular laboratory to sequence beta-globin gene (HBB) and the result of sequencing was as follows:
Wild-type sample
B-Thalassaemic patient sample
1. What is the type of the detected mutation? (Mutation is indicated by an arrow), give the mutation type based on the change in the sequence.
2. The protein product of this mutation is R50P. How would you classify this mutation based on the structure of produced protien?
3. The outcome of this mutation is a less active DNA polymerase. How would you classify this mutation based on the function of produced protien?
Looking at metabolic biochemistry, summarise how each pathway relates to each other - looking at glycolysis, glycogen, glycogenolysis, glycogenesis
What is the difference between mortality and reproductive rates? Do you think that they equally make an impact on population growth? If yes or no, why?
Estimate the consequence of a DNA mutation, within the first exon of a gene, that results in a change from TAT, which codes for Tyrosine, to TAA?
q1. a. how are bacteria cells adapted to live in the hypnotic environment?b. how are amoebas protozons adapted to live
In what form is most carbohydrate taken in a normal diet
Which statement is the most correct regarding transcription/translation?
BOTH FROGS AND DUCKS HAVEW EBBED FEET. MOREEVER DUCKS ARE MOVE CLOSELY RELATED TOPERCHING BIRDS HAN TO FROGS. EXPALIN THE PROCESS THATRESULTED IN BOTH FROGS AND DUCKS HAVING FEET THATARESIMILAR
Research online and find a recent medical error that made the news. What were the ramifications for the patient and/or staff?
The voting public is educated to cast their votes based on the correct interpretation of factual data instead of the influence of fake news?
In preparation for this discussion watch the following videos: VIDEO LINKS WILL BE POSTED BELOW
Cyanide permanently disables C3 only. How does cyanide kill people?
1. Gastroesophageal reflux 6. List some things that increase the risk of hiatal hernia
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