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Question - Recent advances in molecular biology have resulted in a new therapeutic process called RNA interference (RNAi). The purpose of RNAi is to silence the expression of unwanted genes by targeting the destruction of the mRNA transcript. Small interfering RNA (siRNA) are short pieces of double-stranded RNA engineered by a scientist. Inside the cell, the double-stranded siRNA unwinds, the anti-sense siRNA strand complimentarily binds to the mRNA of interest, which is then headed for mRNA degradation. As a result, protein is not translated and expressed. In treating colorectal cancer you are interested in silencing the expression of a mutated gene called APC. The template strand of the APC gene is 3'-ATTGCGTAG-5'. For your RNAi experiment, what is the seuqence of the anti-sense siRNA strand needed to silence APC expression?
Face and body creams that are marketed to women in order to "rejuvenate the skin, and get rid of the fine lines and wrinkles" consists of large quantities of collagens.
Introduction to cancers. Describe to the audience the characteristics of a cancer cell. Indicate which cancer is the focus of your presentation.
Potentially, using the genetic code as it exists, nature could have used 63 amino acids. Why do you think it only uses 20? What element is found in protein but not in carbs or protein? And where else is this element very abundant?
What is the only crainial nerve that enters and leaves the skull? How does fermentation differ from the Krebs cycle? Are microfilaments and lybosomes in both plant and animal cells?
Determine what can a disease like familial hypercholesterolemia tell us about the effects of cholesterol on the people without the disease?
If you did a three-point test cross with genes A, B and C, and only genes A and B were linked, what recombinant frequencies would you see for the 3 pairs of genes, AB, AC, and BC
Beriberi is caused by a deficiency of thiamine in the diet. Severeberiberi causes an increase in pyruvate concentrations in blood and urine. Explain this observation.
1. Hypothesize why some substances were not metabolized, while others were. Research the chemical formula of Equal and Splenda and explain how it would affect respiration.
How is knowledge of DNA and technology being used today to do things that we could not have done 50 years ago? How does control of gene expression affect biotechnology? What is your personal experience with DNA technology?
Discoveries in DNA, cell biology, evolution, biotechnology have been among the major achievements in biology over the past 200 years with accelerated discoveries and insights over the last 50 years
Was evolutionary pressure that contributed to the echinoderm nervous system development likely due to selection for those animals capable of forward locomotion?
Describe how the information encoded by a length of DNA is used tobuild proteins in a eukaryotic cell. What are two mechanisms of gene regulation in a eukaryoteorganism.
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