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Tay-Sachs disease (infantile amaurotic idiocy) is a rare human disease in which toxic substances accumulate in nerve cells. The recessive allele responsible for the disease is inherited in a simple Mendelian pattern. For unknown reasons, the allele is more common in populations of Ashkenazi Jews of eastern Europe.
A woman is planning to marry her first cousin, but the couple discovers that their shared grandfather's sister died in infancy from Tay-Sachs disease. What is the probability that the cousins' first child will have Tah-Sachs disease, assuming that all people who marry into the family are homozygous normal?
Explain how Mendel's scientific approach enabled his genetic experiments to be successful and describe Mendel's law of segregation and explain its' mechanism based on molecular biology.
Determine the suitable measure of the association between alcohol use and CHD in both the smokers and the non-smokers.
A set of Mendelian crosses involving two traits is performed. The first cross is between a plant with green and wrinkled seeds and a plant with yellow and smooth seeds.
Ti make toluidine blue stock solution, you add 1 gram of tolonium chloride to 100mL of 70% alcohol. In order to utilize this stain, you add 5mL of the stock solution to 45mL of 1% NaCl solution.
Describe the way epidemiologist calculate the frequency of cases when it comes to prevelence and incidence. Then discuss some of the major sources of disease tranmission.
A protein is a trimer, which you suspect may exhibit cooperative binding. Every monomer contains a single binding site for the ligand, A. To investigate this you get the this data shown with total=20uM.
Explain why DNA is the most favorable molecule for genetic material and how RNA compares to it in this respect.
Ed Rivers, a third-year medical student, was alone in hospital emergency room one night. It was unusually quiet in the ER, so the residents were getting some much required sleep.
The resting potential of a neuron is approximately -60mV. Neurons maintain this electric potential by maintaining a balance of ions inside and outside the membrane. Which of the following is the most significant factor in determining this balance.
Consider you could micro-inject the cytochrome c within the cytosol of the wild-type cells and of cells which were doubly defective for Bax and Bak.
Sinorhizobium meliloti can be protected from osmotic stress by the presence of certain disaccharides. Dan Orr found that sucrose does a fine job as an osmoprotectant for our strain of S. meliloti,
Since it takes 40 min. to replicate the E. coli chromosome, how can the cell have a cell cycle of 35 minutes?
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