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A school nurse examined a population of 1,000 children in an attempt to detect nearsightedness (NS). The prevalence of myopia in this population is known to be 20%. The sensitivity of the nurse's examination is 65% and its speci?city is 82%. All children labeled as "positive" (i.e., suspected of having myopia) by the school nurse are sent for examination by an optometrist. The sensitivity of the Optometrist's examination is 98% and its speci?city is 90%.
1. What is the positive predictive value (PPV) of the Optometrists exam? Provide an interpretation. How does this value compare/contrast with the PPV from the nurse's exam?
2. What is the negative predictive value (NPV) of the optometrists exam? Provide an interpretation. How does this value compare/contrast with the NPV from the nurse's exam?
3. What is the overall sensitivity of the sequential examinations? Provide an interpretation.
4. What is the overall speci?city of the senuenttal examinations? Provide an interpretation.
HINT: Need to consider the test negatives from both examinations
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