What is the outcome you are interested in studying

Reference no: EM133207563

Assignment: Research Project: Design and Analysis of a Research Study

Overview: The purpose of this assignment is to use the material you have learned in class to develop a research study involving a health topic.In this project, you will use your knowledge about research design to propose a study that will address a key public health issue. You may work in a group or alone. You (and your fellow group members) must pick a specific exposure and outcome that interests you and develop a research hypothesis. Your group will design an appropriate study to test your hypothesis using the epidemiologic concepts covered in class.You will then analyze mock data and evaluate your findings.

Tasks:

1. Each following lecture, you will complete a specific section of this worksheet.

2. Once the worksheet is complete you will receive an excel worksheet with a mock dataset to analyze.

3. After analyzing your data you will interpret the data and identify the strengths and limitations of your study.

4. You will then right a research abstract to describe all of your work.

Complete the following sections to design your research study. You should be able to complete questions 1-4 after the experimental research lecture. After each subsequent lecture, you can add the evaluation of the study design we reviewed. After all study designs have been evaluated, choose the design that would work the best to test your hypothesis.

A. State your hypothesis

B. Why did you choose this topic (what is its importance or relevance to the field?

C. Study Variables

1. Define your Exposure:

a. What is your exposure of interest?

b. What is your control group (or second exposure forcomparison)?

2. Define your outcome

a. What is the outcome you are interested in studying?

b. What is your case definition?

3. Other variables of interest?

a. Are there any other variables you think are important to consider? (ex: age, sex/gender, disease severity, etc...)

D. Evaluate the utility of each of the following study designs in testing your hypothesis?

1. Experimental

a. Would this study design work?

b. What are the benefits of using an experimental design?

c. What are the limitations of using an experimental design?

2. Cohort

a. Would this study design work?

b. Would use a prospective or retrospective design? Why?

c. What are the benefits of using a cohort design?

d. What are the limitations of using a cohort design?

3. Case Control

a. Would this study design work?

b. What are the benefits of using a case-control design?

c. What are the limitations of using a case-control design?

4. Cross Sectional

a. Would this study design work?

b. What are the benefits of using a cross sectional design?

c. What are the limitations of using a cross sectional design?

E. Which of these study designs would you select to conduct your study in the real world?

F. Do you need IRB approval for your study? ___Yes ____No Why?

G. Do you need a Data Safety Monitoring Board for your study? ___Yes ____No Why?

H. Define your population:

1. Who will you study?

2. Who will you exclude from you study?

I. Enrollment:

1. How many people will you study?

2. Describe how you will enroll your subjects into your study:

J. Study Design Tools:

1. What tools would you use to strengthen your study (make sure they are appropriate for the study design you selected):

a. Randomization
b. Random allocation ((choose this one)
c. Restriction ((choose this one))
d. Stratification
e. Matching
f. Blinding
g. Double Blinding

2. Describe how you will use the tools selected above:

Congratulations! You have conducted your study. Submit the information above to receive your data. Once you have data you can proceed to the next page.

K. Results:

1. What calculation will you use to determine the measure of association?

a. Odds Ratio
b. Prevalence Ratio
c. Relative Risk ((choose this))

2. Complete the 2x2 table below with a summary of your data:

Outcome No Outcome Total
Exposed
Not Exposed
Total

3. Calculate your measure of association (show your work):

L. Conclusions:

1. Interpret your findings:

2. Circle the guidelines for causality that provide evidence that your results is accurate and state why:

a. Temporal Relationship:
b. Strength of Association:
c. Dose-Response Relationship:
d. Replication of Findings:
e. Biologic Plausability
f. Consideration of Alternate Explanations:
g. Cessation of Exposure:
h. Specificity of the Association:
i. Consistency with other Knowledge:

3. List at least 3 limitations that may have effected your study results:

4. What would you change about your study design to improve future research?

M. Draw a flow chart for your study.

Reference no: EM133207563

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