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Isotonic saline contains 0.9% NaCl, what is the osmolarity of isotonic solution?
The molecular weight of human serum albumin is 67,000 g/mol and the concentration of the protein in the serum is about 60g/L. If you want to make an isotonic solution of serum albumin (60g/L or 6%) with NaCl for intravenous injection, what is the percentage of NaCl should be in this solution? Why does the protein contribute so little to the osmolarity of the soultion?
Hint: The osmolarity of NaCl plus albumin should equal to the osmolarity of isotonic solution. Use molar concentrations for all the calculations.)
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