What is the mutation load for this locus

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Reference no: EM13159848

A particular disease is determined by a recessive gene h. Of theindividuals homozygous for hh, 1/4 die before age 5. Each of theremaining hh individuals produces only 4/5 as many progeny, on theaverage, as HH or Hh individuals. The mutation rate for H --> his 1.6e-6.

(a) At equilibrium what are the frequencies of allele H and h andof genotypes HH, Hh, and hh?
(b) What is the mutation load for this locus?
(c) Suppose that, due to radioactive fallout, the mutation rateincreases to 3.2e-6. What will be the mutation load in the firstgeneration after this change occurs?
(d) What will be the mutation load after a new equilibrium has beenreached?

Reference no: EM13159848

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