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Why can't a monomeric receptor tyrosine kinase recruit proteins to the receptor? What would happen if the GTP-ASE protein(GAP) were inhibited?
EDIT: I have found the answer to the the second question posted here. However, I believe I have discovered the answer to the first question, but I fail to understand it. Can someone simplify it into english?
The most abundant class of enzyme linked receptors are receptor tyrosine kinases which respond to signal molecules call for proliferation, differentiation, or survival of different cell types. In response to ligand binding, the receptors oligomerize and the cytosolic tails-which contain tyrosine kinase activity-phosphorylate each other's tyrosine residues. This autophosphorylation increases the kinases activity of the receptor, and creates binding sites for different proteins. The signaling receptor proteins require phosphotyrosine to bind; hence they do not interact with the inactive monomeric receptor.
Another temperate biome planned for the biome garden is the temperate grassland/desert biome. Your friend is particularly interested in developing temperate grassland. Discuss some of the considerations involved in establishing such grassland under g..
Examine how the pancreatic endocrine hormones glucagon and insulin work antagonistically to maintain homeostasis in the body, throughout times of feast and times of famine.
now a days, scientific advances are being made at an astounding rate, and nowhere is this more evident than in our understanding of the biology of heredity. Using DNA as a starting point, do you believe there are limits to the knowledge people sho..
Compare the divisions of the autonomic nervous system's effect on heart rate and stroke volume.how to Describe an action potential.
What blood test would be performed before starting the transfusion. Calcium levels in blodd are dropping to dangerously low levels. The hormone PTH is released and almost immediately calcium levels begin to rise. Shortly after, PTH release slows. Is ..
To be able to run and play requires lots of energy. The Oreo supplies both dietary fiber and glucose that are metabolically quick energy sources.
Suppose you have a light chain genome with 64V regions and 8J regions. If you had repeated attempts at recombination, how many dissimilar attempts would be made when the middle region of both V and J is the segment chosen at each recombination.
What percent of the population are homozygous dominant. What do you assume would be the effect on the switch of reversing orientation of one of the hix sites.
Glucose is experimentally synthesized with C-14 at carbon 1, and used as a substrate for aerobic metabolism. Where is the label at the end of glycolysis.
Using examples, discuss types of genetic mutations that result in faulty proteins and disease,
A batch animal cell culture has a productivity of 1.8 g/L*day, with a MUmax=0.5 days, a 10% inoculums and a turnaround time of 5 hours. If a continuous culture could operate at a dilution rate of 90% MUmax, explain what would be the productivity.
Specify whether the taste of fresh water surprised you or not? Explain if your perception of coarseness change or not?
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