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The study of the rates of absorption and elimination of drugs by organisms is Pharmacokinetics. Elimination is usually slower than absorption and is a more important determinant of availability of a drug for binding to its target. A drug can be eliminated by many mechanisms, such as metabolism in the liver, intestine, or kidney followed by excretion of breakdown products throughout the body. After intravenous administration of a medicine, the blood plasma of a patient was analyzed for the drug in the blood stream at time, t. The data are shown below
a) What is the kinetic order of the elimination of the drug from the blood stream?
b) What is the rate constant of the reaction?
c) If the elimination is a first-order process, what is the elimination half-life?
Show all the steps in the mechanism for the following reaction, When benzene is mixed with deuterated sulfuric acid, deuterium is slowly incorporated onto the ring. Show the mechanism for this reaction and explain how this relates the sulfonation of ..
This assignment inhibits chemistry Laboratory Questions.
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