Reference no: EM133630150
Assignment:
Part A
Content: Pick something from this case study that stood out to you in some way. It could be something new you learned, something that made you think about this subject in a different way, or something you found interesting. Share the content you chose with the class and explain why you chose it.
Concern, or question: After reviewing this case study, what is one question or concern this content raised in your mind? This could be something that didn't settle well with you, a question you have for future research or consideration, or something you'd like to know more about. Share this concern with the class and explain why you chose it.
Connection: Why is the content in this case study important? How does it relate to the real world and/or why is this case study important? You could draw upon real world examples like something you read in the news recently, something from your favorite TV show, or any other form of connection between this case study and the importance of its content outside the classroom.
Part B
1. What is the grapefruit diet, and is there research data to support its effectiveness?
2. What is an enzyme?
5. How are P450 drugs involved in the normal pharmacokinetics of drugs like Lipitor?
6. What kinds of drug side effects can be seen if a patient's P450 enzymes are not functioning at a normal level, through their own unique biochemistry or through other drug or substance interactions? 7. What is an enzyme inhibitor? What is furanocoumarin, and what is its relationship to grapefruit?
8. How do grapefruit and grapefruit juice affect P450 enzyme activity? How does this result in a higher concentration of Lipitor in a person's blood?