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1. One aspect of aging appears to be related to telomeres. Every time a chromosome is duplicated in the S Phase of interphase, the ends of the chromosome (i.e. telomeres) unravel. This sets a limit of around 50 cell divisions before the chromosome unraveling effects genes. Explain the significance of this.
2. What is the difference between DNA, chromatin, and chromosomes? What is the significance of each form?
In the fungus Neurospora, the td+ allele is needed for the cells to build the amino acid tryptophan. The mutant allele td results in an inability of the fungus to make its own trp,
List 4 major types of virulence factors associated with bacteria, and briefly describe how each one facilitates pathogenesis. How do pathogens generally differ from normal flora? Where do the genes for virulence factors usually come from? What are..
Marco was in a car accident and lost a significant amount of blood. The doctors knew Marco had type O blood, but due to a terrible error, Marco received blood that was type A. This caused a severe immune reaction, but luckily Marco survived. Expla..
With regard to bringing solutes into the cell across the plasma membrane, discuss the advantages and disadvantages of diffusion, facilitated diffusion, active transport, and endocytosis.
Explain how nucleotides are enzymatically linked together during nucleic acid synthesis. Identify the specific carbons on the sugars that are involved (between what carbons is the phosphodiester bond formed?).
For each of the E. coli strains given below, estimate the effect of the genotype on expression of the trpE and trpC genes in the presence and absence of tryptophan.
Three groups of cyclists shown above consumed 3-different types of diets: high-carbohydrate, a diet mixed in carbohydrates, or a diet higher in protein and fat.
Monkeys infected with "Devil Pox" survive depending on their genotype at a single locus. AA individuals survive 50% of the time. AB individuals survive 75% of the time.
Use a chi-square test, test whether these two loci show independent assortment? How would you describe the frequency of the progeny genotypes?
In peas, the genes a, b, c, d, e and f are linked on chromosome V and in the order given and the map distances are RF(a-b)=7 cM, RF(b-c) = 17 cM, RF(c-d) = 12 cM, RF (d-e) = 14 cM RF(e-f)= 10 cM.
Describe any 3 effects that alcohol can have on the liver. Which of these are long-term and which are short-term effects?
The pituitary gland secretes thyroid-stimulating hormone (TSH), which stimulates the thyroid gland to secrete the thyroid hormone (TH). TH has a negative feedback influence on TSH.
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