What is the clinical signature of injury associated

Reference no: EM133357124

Questions:

• Does the drug cause clinically significant DILI in the target treatment population?
• What is the clinical signature of injury associated with the drug?
• What are the ranges of doses & duration are associated with increased risk?
• What are the critical patient susceptibility factors?
• What incidences of mild & severe liver injury can be predicted in a large treatment population?

Reference no: EM133357124

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