What is the chance that mary and james will have a boy with

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Question: Mutations in the SLC26A2 gene, causes disastrophic dysplasia, an autosomal recessive condition. Mutations in the FGFR3 gene, causes achondroplasia, an autosomal dominant condition that is also lethal in the homozygous state. Mary (who suffers from anchondroplasia, has a father who has diastrophic dysplasia and a mother with achondroplasia) marries James (who suffers from achondroplasia, has a mother who has diastrophic dysplasia and a father with achondroplasia). What is the chance that Mary and James will have a boy with only diastrophic dysplasia?

Provide a clearly labelled step by step account of your calculations. DO NOT provide the pedigree.

explain with lots of details,

Reference no: EM133431190

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