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What is the average number of mutations introduced

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Question - 1- As discussed, new mutations are part of DNA replication. The overall error rate of DNA biopolymerase in the replisome is 10-8 errors per base pair in humans. Repair enzymes fix 99% of these lesions. The human haploid genome is 3.2 * 109 bp.

a. What is the average number of mutations introduced when the genome is replicated?

- In males, there are approximately 400 cell divisions between zygote and production of a sperm cell.

b. How many mutations are to be expected in every sperm cell?

- In a female, there are about 30 cell divisions between zygote and production of egg cell:

c. How many mutations are expected in an egg cell?

d. How many mutations are expected in a new zygote?

e. Give a brief explanation what these mutations can result in from the evolutionary view, assuming they are a mutation that causes an amino acid change in a protein.

Reference no: EM131708764

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