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Question - 1- As discussed, new mutations are part of DNA replication. The overall error rate of DNA biopolymerase in the replisome is 10-8 errors per base pair in humans. Repair enzymes fix 99% of these lesions. The human haploid genome is 3.2 * 109 bp.
a. What is the average number of mutations introduced when the genome is replicated?
- In males, there are approximately 400 cell divisions between zygote and production of a sperm cell.
b. How many mutations are to be expected in every sperm cell?
- In a female, there are about 30 cell divisions between zygote and production of egg cell:
c. How many mutations are expected in an egg cell?
d. How many mutations are expected in a new zygote?
e. Give a brief explanation what these mutations can result in from the evolutionary view, assuming they are a mutation that causes an amino acid change in a protein.
Predict which of the following liquids has greater surface tension: ethanol (C2H5OH) or dimethyl ether (CH3OCH3).
We prepare a buffer by adding 0.4640 mol HNO3 to 0.5528 L of a solution containing 2.061 M trimethylamine [(CH3)3N, Kb = 6.500x10-5]. What is the pH of this buffer
Explain how these products are produced by showing the mecahnism involved. (draw).
Nuclides below the valley of stability can become more stable through which of the following processes
What mass of ammonium chloride should be added to 2.65 of a 0.145 in order to obtain a buffer with a of 9.65
By titration it is found that 80.1 mL of 0.114 M NaOH(aq) is needed to neutralize 25.0 mL of HCl(aq). Calculate the concentration of the HCl solution
Problem- Explain with an appropriate diagram why amphipathic molecules tend to form micelles in water. What force drives micelle formation
Silver metal crystallizes in a face-centered cubic structure. The radius of the silver atom is 144.5 pm. Calculate the density of the metal in g/cm3.
Phosphorus-32 decays by beta emission to form sulfur-32. Explain how many half-lives have passed in the reaction shown here
Would you choose a dilute acid (say 50 mM HCl or a dilute base (again, say 50 mM NaOH) or a buffer near neutral pH? Why? (Hint: Think about what factors govern water solubility and how pH will affect one of them.)
Gaseous butane will react with gaseous oxygen to produce gaseous carbon dioxide and gaseous water . Suppose 49. g of butane is mixed with 150. g of oxygen.
Four atoms are arbitrarily labeled W, X, Y, and Z. Their electronegativities are as follows: W=4.0, X=3.0, Y=2.0, and Z=1.5. If the atoms of these elements form the molecules
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