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The following kon and koff rates for the interaction of antibody (IgG) and a 40 amino acid peptide were determined via surface plasmon resonance (a Biacore machine) to be: kon = 210 nM-1·sec-1, koff=11,000 sec-1
(a) What is the dissociation constant for the peptide:IgG interaction?(b) What is the association constant for the peptide:IgG interaction?(c) If the binding study were performed at 298K, what is the ?G (in kJ/mol) of binding?
Think about the pathology of a cytokine storm, select possible strategies that would be likely to diminish the harmful effects of superantigen toxins.
The developing fetus has a different kind of hemoglobin than most normal adults. Fetal hemoglobin consists of two chains and two chains, whereas adult hemoglobin consists of two chains and two chains.
If populations are sustaining growth at r = 0.088 and the population in 2001 is 3000 individuals, in what year would snow geese be taken off an endangered species list.
You are the lead engineering in charge of running a single chemostat reactor (75 L) to produce a therapeutic protein from an engineered organism.
Define stable equilibrium in population genetics. Describe the kind of data that you would need to collect about a population to conclude that it is in a stable equilibrium.
Joe Average has just been frightened by a very loud noise as he was taking a very difficult physiology exam. In response, his adrenal glands have released a large amount of adrenaline into his circulation. Which of the effects would you expect to ..
Think about a mature megaspore mother cell containing twenty DNA molecules to answer the following questions concerning meiosis.
What are the three central elements of chemiosmotic theory for coupling oxidation to phosphorylation in mitochondria?
Tips on solving this: Identify the factors that affect blood pressure; Describe the individual and collective effects of the Lasix, hot water and alcohol on blood pressure.
These are questions from Western Blotting Lab. Please answer any question you know.
K+ leak channels are found in the plasma membrane. These channels open and close in an unregulated random fashion. What of they accomplish in a resting cell?
A plant that has seed very rich in an oil that can be directly used as a biofuel to power vehicles has been discovered. the plant is able to grow on a marginal farm land and thus fuel oil production would not compete with food production.
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