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We want to induce a bacterial cell to produce a simple mammalian protein. The protein
sequence is: GGPQGILGQGGK
(i) How many DNA and RNA sequences are possible that give you this protein sequence?
(ii) What is one such mRNA sequence that would encode for this protein?
(iii) What is the corresponding DNA sequence that would needed for production of this protein?
The frequency of the dominant allele A in a population is 65% and the recessive allele a is 35%. Calculate the genotypic frequency within the population using the Hardy-Weinberg equation.
You learn that a certain strain of bacteria has an interesting replication pattern. Every 5 hours, the number of bacteria colonies increase by 17%.
Explain the process of viral replication; discuss both normal and retroviruses, and comment on the implications of this process for genetic engineering.
Discuss how do the amplitudes of the finger twitches with different weights compare to each other? Explain why did the amount of work decrease when heavier weights were used?
A section of the E. coli genome that encodes the pheM protein. Write out and label: the reverse complement, the mRNA sequence.
Can you imagine any potential advantage that would result from the duplication of a region of a chromosome? Briefly explain what/why.
A botanist takes a sample of 300 plants from a population and determines the genotype of each one for an esterase locus. The locus has two alleles segregating in the population
A mutation occurs in the lac repressor protein such that it can no longer bind to allolactose. What effect will this mutation have on expression of proteins of the lac operon in the presence of lactose?
The drug methotrexate has been reported to cause fetal death and/or congenital anomalies, therefore, it is not recommended for women of childbearing potential.
At 45C, the vapor pressure of water for a glucose solution in which the mole fraction of glucose is 0.080 is 65.76 mmHG. Calculate the activity and activity coefficient of the water in the solution.
Assume you have an unknown DNA that you know is phage DNA - It is either T7 or lambda. You perform a restriction enzyme digest and run the results on a gel.
Prions are "infectious" proteins that will alter the structure of wild type proteins and turn them prionic. Explain the relationship between structure and function for the following molecules: - lipids - phospholipids
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