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Q1. After reviewing the FDA's guidance on expedited programs for serious conditions, discuss the pros and cons of priority review and accelerated approval programs.
Q2. What is an FDA advisory committee meeting?
Discuss the importance of regulatory meetings in the development of medicinal products for human use.
Draw the correct molecular geometries of the following covalent compounds. Use the electronegativity differences between the atoms in each bond pair to determine the presence and direction of individual bond dipoles in each molecule.
At 20 degrees C, 0.164 mg of H2 dissolves in 100.0 g of water when the H2 pressure above the water is 1.000 atm. Find the Henry's law constant for H2 is water at 20 degrees C.
Nickel has a face-centered cubic unit cell. The density of nickel is 6.84 g/cm3. Calculate a value for the atomic radius of nickel.
The combustion of butane produces heat according to the equation 2C4H10(g) + 13O2(g) -> 8CO2(g) + 10H2O(l) ->H°rxn = -5,314 kJ/mol What is the heat of combustion per gram of butane
Explain which of the subsequent molecules would you expect to dissolve in water? Diethyl ether? Briefly define based on your understanding of IM forces why or why not
When sodium chloride is strongly heated in a flame, the flame takes on the yellow color associated with the emission spectrum of sodium atoms. The reaction that occurs in the gaseous state is Na^+(g) + Cl^- (g) ----> Na (g) + Cl (g)
A 97.0 mL sample of 0.0200 M HCl is titrated with 0.0400 M RbOH solution. Calculate the pH after the following volumes of base have been added. (a) 22.3 mL pH = (b) 47.5 mL pH = (c) 48.5 mL pH = (d) 49.5 mL pH = (e) 94.1 mL pH =
If the volume of 0.200 M NaOH needed to neutralize 0.410 g of an unknown acid is 35.0 mL, what is the molar mass of the monoprotic acid
Determine the activation barrier for the reaction. What is the value of the rate constant at 15
Sodium has a greater first ionization energy than sulfur, and the reason for this is because Na has a greater effective nuclear charge (Zeff) than S.
Draw the structure of the organic product that is formed when 3-methylcyclopentanol is treated with the following reagents: 1) TsCl, pyridine; 2) NaCN.
Draw the structure of Caffeine. Skeletal form only. Locate 2 bonds in the molecule that are obviously polar covalent.
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