What effect does protein binding have on drug availability

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Reference no: EM133705638

Assignment

Directions:

For each scenario below, answer the questions below using clinical practice guidelines where applicable.

Explain the problem and explain how you would address the problem pharmacologically.

If prescribing a new drug, write out a complete medication order just as you would if you were completing a prescription.

To Prepare:

1) Review the case study posted in "Announcements" by your Instructor for this Assignment
2) Review the information provided and answer questions posed in the case study
3) When recommending a medication, write out a complete prescription for the medication
4) Whenever possible, use clinical practice guidelines in developing your answers when possible
5) Include at least three references to support your answer and cite them in APA format.

Use at least 3 sources for each scenario and cite sources using APA format.

I. A 52-year-old man was recently discharged from the hospital following treatment for a trial fibrillation. He was discharged on Warfarin 5 mg po q day and Amiodarone 200 mg tid. His INR is 8.8. What interaction has occurred with these 2 medications? What changes in his medications would you make?

II. A 44-year-old women is currently taking Glipizide and Phenytoin. She has a new prescription for Ceftriaxone. All three medications are known to be highly protein bound. What effect does protein binding have on drug availability? How would you manage this patient's medication?

III. Name two drugs that are highly affected by the first pass effect. As a prescriber, what actions would you take in prescribing these drugs to counter the first pass effect?

IV. James is a 49-year-old male that was prescribed atenolol for his high blood pressure. James states that he only occasionally takes the medication because he does not like the side effects. What information would you provide to the patient at his visit? How would you manage his medication?

Reference no: EM133705638

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