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Question: Drug for Rheumatoid Arthritis Read the portion of the abstract of a scientific study that appears below, and then answer the questions that follow. "Methods: In this double-blind, placebo-controlled study, 611 patients were randomly assigned, in a 4:4:1 ratio, to [receive] 5 mg of tofacitinib twice daily, 10 mg of tofacitinib twice daily, or placebo. The primary end point, assessed at month 3, was the percentage of patients with at least a 20% improvement on the American College of Rheumatology scale (ACR 20), Results: At month 3, a higher percentage of patients in the tofacitinib groups than in the placebo groups met the criteria for an ACR 20 response (59.8% in the 5-mg tofacitinib group and 65.7% in the 10-mg tofacitinib group vs. 26.7% in the placebo group, P 6 0.001 for both comparisons)."a. Identify the treatment variable and the response variable.
b. Was this a controlled experiment or an observational study? Explain.
c. Do the sample percentages suggest that the drug was effective in achieving a 20% reduction in symptoms?
d. What does the small p-value show?
e. Can you conclude that the use of tofacitinib increases the chances of a 20% improvement in symptoms? Why or why not?
MATH1550H: Assignment: Question: A word is selected at random from the following poem of Persian poet and mathematician Omar Khayyam (1048-1131), translated by English poet Edward Fitzgerald (1808-1883). Find the expected value of the length of th..
MATH1550H: Assignment: Question: what is the least number of applicants that should be interviewed so as to have at least 50% chance of finding one such secretary?
MATH1550H: Assignment: Question: Experience shows that X, the number of customers entering a post office during any period of time t, is a random variable the probability mass function of which is of the form
MATH1550H: Assignment:Questions: (Genetics) What is the probability that at most two of the offspring are aa?
MATH1550H: Assignment: Questions: Let’s assume the department of Mathematics of Trent University has 11 faculty members. For i = 0; 1; 2; 3; find pi, the probability that i of them were born on Canada Day using the binomial distributions.
Caselet on McDonald’s vs. Burger King - Waiting time
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